Search results for: 'Peptide'

类别: Aminopeptidase ACE Calpains Cathepsin Gamma Secretase MMP Thrombin Other Proteases Endogenous Metabolite Mitochondrial Metabolism PAI-1 Ser/Thr Protease Caspase Bax Bcl-2 Family IAP TNF-α Other Apoptosis PD-1/PD-L1 interaction Pyroptosis Histone Acetyltransferases Histone Demethylases Histone Methyltransferase HIF Protein Ser/Thr Phosphatases Citrullination Histones/Histone Peptides PPAR Neuronal Metabolism P450 Others Bone Growth & Remodeling Carbohydrate Metabolism Cofactors & Vitamins Dyslipidemias Metabolic Syndrome Necrosis Nutrient Sensing Reproductive Biology Sterol Biosynthesis PKA p38 JNK cAMP Broad Spectrum Protein Kinase Inhibitor EGFR Insulin Receptor Src Trk ATM/ATR CDK DNA/RNA Synthesis Casein Kinase Akt AMPK GSK-3 PI3K S6 Kinase Antibiotic HCV HIV Antifungal Bacterial Parasite SARS-CoV Coronaviruses Dengue Entry/Fusion Inhibitors Yellow Fever COVID-19 Antiviral Microtubule/Tubulin Dynamin ECM & Adhesion Molecules Cytoskeleton & Motor Proteins Endomembrane System & Vesicular Trafficking Proteolysis Autophagy Proteasome STAT PKC Integrin PAR1 Neuropeptide FF/AF Receptors Formyl Peptide Receptors 5-HT Receptor Adrenergic Receptor Apelin Receptor Angiotensin Receptor Bombesin Receptors Bradykinin Receptors Calcitonin and Related Receptors Cannabinoid Receptor CaSR CCK1 Receptors CCR Chemokine Receptors CRF2 Receptors CXCR Endothelin Receptor ETB Receptors Galanin Receptors Ghrelin Receptors GIP Receptor Glucagon Receptor Melanin-concentrating Hormone Receptors Melanocortin (MC) Receptors Motilin Receptor Non-selective CRF Neurotensin Receptors NOP Receptor NPY Receptors Orphan 7-TM Receptors OX Receptor Oxytocin Receptors Peptide Receptors Protease-Activated Receptors Secretin Receptors Somatostatin Receptor Vasopressin Receptor Ras Urotensin-II Receptor VIP Receptors Neuromedin U Receptors mAChR Neurokinin Receptor Notch Wnt/β-catenin Cancer stem cell YAP AMPAR Calcium Channel Pannexin-1 Potassium Channel TRP Channel Kainate Receptors Na+/K+ ATPase iGluR Cancer Biology Peptides Ras-like GTPases Tumor Microenvironment Cell Migration & Metastasis GnRH Opioid Receptor Thyroid hormone Receptor TRH Glucocorticoids & Mineralocorticoids AChR Alzheimer Amyloid β CGRP DAPK Gap Junction GluR Histamine Receptor Neuroscience Peptides Nicotinic Receptor Substance P/NK1 Receptor CaMK Behavioral Neuroscience Neuroendocrinology Neuroprotection Ophthalmology Pain Research Parkinson Prion Diabetes NAFLD & NASH Obesity Peptide Inhibitors and Substrate Other Signal Transduction Papain TLR NF-κB Interleukin Related Complement System IFNAR NO Synthase NOD-like Receptor (NLR) STING Reactive Oxygen Species Apoptosis Glutathione Adaptive Immunity Allergy Arthritis Autoimmunity Gastric Disease Innate Immunity Pulmonary Diseases PSMA Acute Phase Reactants Arrhythmia Atherosclerosis Chronic Kidney Disease Coagulation & Hemostasis Diabetic Nephropathy Endothelium Erythrocytes & Hemoglobin Heart Failure Hypertension Hypotension Lipoproteins Myocardial Contractility Myocardial Hypertrophy Myocardial Infarction Serum Proteins Smooth Muscle Cells Stroke Vasoconstriction Thrombosis Vasodilation ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC Antioxidants Carbohydrate Oxidation Lipid Peroxidation Pro-Oxidant Activity Adenylate cyclase AT Receptors Cell Penetrating Peptide Cytokine Enzyme Substrates / Activators Fluorescent Probes Glycoprotein Guanylate Cyclase Guanylyl Cyclase MDR multidrug resistance Myosin Natriuretic Peptide Receptors Nitric Oxide Renin Tachykinin Transcription Factors Cyclase Toxicology Antiparasitics Toxins Peptide Coupling Reagents Amino Acids and Derivatives N-Protecting Reagents Other Reagents Other Resin and Derivatives Natural Products Screening Library Cyanine Dyes Affinity Probes Enzyme Substrates Fluorescence Biochemical Assay Reagents B type Natriuretic Peptide Transferase Insulin Macrophage Migration Inhibitory Factor GHRP GLP Glucagon Peptide Hormones Other Natural Proteins Other Superoxide Dismutase SARS Leukotrienes Lipid-Based Drug Delivery Prostaglandins Neuropeptides Tag Peptides Amyloid β protein Inhibitors and Substrates Peptide Epitopes Peptides for Drug Delivery Featured Products Food-Borne Illnesses MRSA Pneumonia STDs Tuberculosis Candidiasis Leishmaniasis Quorum Sensing Hepatitis

Cat.No. 产品名称 Information
GA22856 H-Pro-NHEt . HCl The C-terminal residue of highly active GnRH agonists as buserelin or leuprorelin replacing the C-terminal Pro-Gly amide of the native peptide hormone.
GA22811 H-Phe-Pro-Arg-OH FPR is a tripeptide analog of the thrombin-receptor-derived peptide SFLLR (H-1408). In the chick chorioallantoic membrane system it inhibited angiogenesis and caused a complete reversal of the angiogenesis-promoting effect of the thrombin-receptor-activating tetradecapeptide (TRAP (1-14), H-8105). FPR has potential applications in the nonthrombotic actions of thrombin, e.g. cancer and inflammation, where angiogenesis is thought to play a pivotal role.
GA22807 H-Phe-Phe-Phe-OH FFF is a bitter-tasting peptide due to its hydrophobicity. As diphenylalanine, triphenylalanine forms ordered nanostructures.
GA22761 Homoglutathione Homoglutathione is a taste-modifying peptide responsible (in combination with γ-glutamyl peptides as γ-Glu-Leu (G-1950) and γ-Glu-Val (G-2015)) for the "kokumi" flavor. Pesticides containing electrophilic centers can be metabolized in legumes via conjugation to homoglutathione (H-3944) or glutathione.
GA22756 H-Nle-Arg-Phe-NH₂ nLRFamide, synthetic analog of flatworm FMRFamide-related peptides (FaRPs) showed considerable myoactivity on isolated muscle fibers of the human blood fluke.
GA22724 H-Met-Arg-Phe-Ala-OH
MET-ARG-PHE-ALA乙酸盐
MRFA is used as a calibration standard in mass spectrometry (ESI). Miao et al. studied Pt(II) complexes of the tetrapeptide by mass spectrometric methods. MRFA has been shown to be a competitive inhibitor of an enkephalin-generating endopeptidase isolated from rat brain. The peptide is a substrate for dipeptidyl peptidase III from human erythrocytes and for snapalysin.
GA22704 H-Lys-Phe-Lys-OH KFK was shown to activate LAP-TGF-β. Linked to elaidic acid, the peptide is used as a cosmetic ingredient.
GA22696 H-Lys-Lys-Lys-Lys-Lys-OH Pentalysine. KKKKK corresponds to the N-terminal sequence of the MARCKS peptide.
GA22693 H-Lys-Gly-Glu-OH A murein peptide sequence (characteristic of peptidoglycan type A4α). As the RGD motif, KGE binds to integrins.
GA22689 H-Lys-Cys-Thr-Cys-Cys-Ala-OH The cysteine-rich peptide KCTCCA represents the C-terminal portion (residues 56-61) of mouse liver metallothionein-I. It shows a strong binding affinity to the metal ions Cd²? and Zn²? and exerts a protective effect against cadmium (Cd²?) toxicity in vivo and in vitro.
GA22656 H-Leu-Val-Leu-Ala-pNA LVLA-pNA, optimal peptide substrate for continuous assay of HSV-1 protease with a kcat/Km value of 100 M?¹s?¹. Other serine proteases did not hydrolyze the substrate.
GA22653 H-Leu-Trp-Met-Arg-Phe-OH LWMRF, analog of FMRF-amide used as model peptide.
GA22652 H-Leu-Trp-Met-Arg-Phe-Ala-OH LWMRFA, analog of FMRF-amide, is cleaved by rat brain cathepsin L. A model peptide with various applications.
GA22649 H-Leu-Ser-p-nitro-Phe-Nle-Ala-Leu-OMe Standard substrate for chymosin activity determination. This peptide is also a good substrate for pepsin, penicillopepsin, and gastricsin.
GA22618 H-Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg-OH The fragment LQVQLSIR corresponding to the C-terminal globular domain of the murine laminin α1 chain (2722-2729) represents the minimal active sequence of AG-73, an active cell-adhesion peptide. LQVQLSIR could be one of the most important biologically active sites of laminin-1, especially in promotion of the malignant phenotype.
GA22597 HIV (gp120) Fragment (308-331) This peptide derived from the V3 loop of HIV IIIB gp120 completely blocks the fusion inhibition activity of antisera to recombinant human HIV proteins. NNTRKSIRIQRGPGRAFVTIGKIG also inhibits the infection of primary human T cells by HIV-1 IIIB, as well as syncytium formation.
GA22593 Hirullin Hirullin, originally isolated from the leech Hirudinaria manillensis, is a hirudin-based fibrinogen recognition peptide inhibitor, which binds efficiently to thrombin (IC??= 4.2 µM, in bovine).
GA22575 H-Ile-Phe-OH
L-异亮氨酰-L-苯丙氨酸
A dipeptide able to self-associate in aqueous solution as a transparent, thermoreversible gel formed by a network of fibrillar nanostructures that exhibit strong birefringence upon Congo red binding. G-2420 and similar dipeptides may serve as models for studying the first steps of the aggregation/fibrillation of amyloid peptides.
GA22534 H-His-Cys-Lys-Phe-Trp-Trp-OH HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3'processing and integration with an IC?? of 2 µM. The peptide is also active on IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus and Moloney murine leukemia virus. It was also found to inhibit the disintegration reaction, suggesting that this hexapeptide acts at or near the catalytic site of IN.
GA22520 H-Gly-Tyr-Gly-OH GYG was used as a model peptide in studies on the UV-absorption behavior and on the nitration of Tyr-containing proteins.
GA22512 H-Gly-Sar-OH
甘氨酰肌氨酸,Glycylsarcosine
Due to its resistance to hydrolysis, glycylsarcosine served as a model dipeptide used to study peptide transport in a variety of cell lines.
GA22509 H-Gly-Pro-Hyp-OH
三肽-29
A peptide DPP-4 inhibitor
GA22504 H-Gly-Pro-Arg-OH GPR could protect cultured rat hippocampal neurons from Aβ peptide-induced cell death.
GA22497 H-Gly-Phe-Ser-OH Thermolysin cleaves this peptide at the Gly-Phe bond.
GA22491 H-Gly-Phe-Gly-OH GFG and GYG (H-3670) were used as model peptides in a study on the nitration of proteins.
GA22488 H-Gly-Phe-Ala-OH Thermolysin cleaves this peptide at the Gly-Phe bond.
GA22487 H-Gly-Pen-Gly-Arg-Gly-Asp-Ser-Pro-Cys-Ala-OH GPenGRGDSPCA (cRGD), a cyclic RGD peptide has been used in the study of vascular wound response. GPenGRGDSPCA caused vasodilation when applied to isolated rat cremaster arterioles. The vasodilation is dependent on interaction of the soluble cRGD sequence with the αvβ3 integrin expressed by smooth muscle cells in the arteriolar wall.
GA22482 H-Gly-Met-Gly-OH A model peptide for studying Met oxidation.
GA22480 H-Gly-Lys-His-OH Lipolytic peptide, corresponds to pTH (12-14).
GA22459 H-Gly-Gly-OEt . HCl
H-GLY-GLY-OET旽CL
Used as a low molecular model compound for the nitrosation of peptides and proteins. CAS-Number (net): 627-74-7.
GA22453 H-Gly-Gly-Ile-OH
甘氨酰-甘氨酰-L-异亮氨酸
The tripeptide GGI stimulates the Na?/Cl?-dependent transport system for opioid peptides in SK-N-SH cells, a human neuronal cell line.
GA22421 H-Gly-Asp-Arg-Ala-Asp-Gly-Gln-Pro-Ala-Gly-Asp-Arg-Ala-Asp-Gly-Gln-Pro-Ala-OH T-cell epitope P11 from the central region of Plasmodium vivax circumsporozoite (CS) protein was the peptide most frequently recognized by sera containing antibodies to the homologous CS protein as determined by immunofluorescence antibody test.
GA22409 H-Gly-Arg-Ala-Asp-Ser-Pro-OH GRADSP is used as negative control peptide for GRGDSP (H-7630).
GA22391 H-Glu-Thr-Tyr-Ser-Lys-OH . 2 TFA ETYSK, a model peptide for the evaluation of analytical methods.
GA22328 Hepcidin-20 (human)
铁调素HEPCIDIN-20(HUMAN)
Hepcidin-20, a degradation product of hepcidin-25 found in plasma and urine, shows an increased antimicrobial activity compared to the full-length peptide, but it is not involved in iron metabolism.
GA22325 Helodermin Helodermin (exendin-2) was originally isolated from the venom of Gila monster (Heloderma suspectum). A high degree of sequence similarities to secretin, VIP, PHI, and GRF from mammal and bird was observed over the entire N-terminal (1-27) sequence. The isolation of helodermin was the first demonstration of the existence of a secretin/VIP-related peptide in an animal that is neither mammal nor bird. Among all known VIP-related peptides, helodermin was the most potent in stimulating cAMP production by NCI-H345 cell line.
GA22324 Hel 13-5 Highly lipid-soluble α-helical amphiphilic cell-penetrating peptide used in combination with phospholipids for developing pulmonary surfactant model systems. Hel 13-5 also binds to nucleic acids. The CPP is a most efficient DNA and siRNA delivering and transfecting agent.
GA22322 Head activator Morphogenic peptide from hydra. The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37.
GA22321 H-D-Val-OBzl . p-tosylate
D-缬氨酸苄酯对甲基苯磺酸盐
Useful building block for introduction of D-valine at the carboxy terminus in conventional peptide synthesis.
GA22175 H-Dab-OH
L-2,4-二氨基丁酸二盐酸盐
Dab is a major constituent of the polymyxin peptide antibiotics. Educt for the synthesis of cyclic amidine ectoine, which is used in skin care products. Dab is as well the precursor of the natural ectoine found in high concentration in halobacteria. In vitro, incubation with Dab irreversibly damages hepatoma cells.
GA22169 H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH₂ The peptide CDPGYIGSR amide, which comprises residues 925-933 of the laminin B1 chain, inhibited both angiogenesis and solid tumor growth.
GA22164 H-Cys(NPys)-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH₂ All D-analog of cell-permeable peptide H-7516.
GA22151 HCV NS4A Protein (21-34) (JT strain) The NS4A fragment GSVVIVGRIILSGR corresponds to the residues involved in the interaction with the NS3 protease. Unlike the NS4A fragment (22-34) derived from the H strain (H-2764), this peptide contains no cysteine residues and is hence more stable.
GA22089 H-Arg-Phe-NH₂ RFamide has been used for raising antibodies employed in ELISA assays for detecting RFamide-type peptides in biological material.
GA22088 H-Arg-Phe-Asp-Ser-OH RFDS, an analog of the RGD peptide RGDS, inhibits cell adhesion. The motif RFDS was found highly conserved in MHC class I (α1 domain) and class II antigens (β1 domain).
GA22078 H-Arg-Gly-Asp-Val-OH Studies using a baboon model showed that RGDV selectively inhibits platelet-dependent thrombus formation in vivo. In a study by Kawahara et al. on the inhibitory effects of adhesion oligopeptides on the invasion of squamous carcinoma cells RGDV was the most effective inhibitor amongst the evaluated peptides.
GA22077 H-Arg-Gly-Asp-Ser-Pro-OH The RGD peptide RGDSP was employed for improving the biocompatibility of titanium dental implant model surfaces. Modification with RGDSP enhanced cell viability in PEG-based hydrogels.
GA22075 H-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH The RGD peptide RGDSPASSKP inhibits fibronectin adhesion to fibroblasts.
GA22062 H-Arg-Arg-Arg-Arg-Arg-Arg-OH Six arginines is the minimum number of residues required for obtaining a polycationic peptide which can effectively penetrate cells.
GA22056 H-Arg(Pmc)-OtBu (free base) Used in the synthesis of peptide primers for cyanophycin, a cyanobacterial reserve polymer.

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