Home >> Signaling Pathways >> Proteases >> Cathepsin


Cathepsins (the term standing for “lysosomal proteolytic enzyme”) are a class of globular proteases that catalyze the hydrolysis of intracellular peptides and also exhibit extracellular functions. So far, a total of sixteen members of human cathepsin family have been identified, which are divided into three subfamilies, including cysteine protease family (cathepsin B, C, F, H, L, K, O, S, V, W, X and Z), serine carboxypeptidase family (cathepsin A and G) and aspartic protease family (cathepsin D and E). Cathepsins are highly expressed in various human cancers with each member playing different roles in distinct tumorigenic processes, including proliferation, angiogenesis, metastasis and invasion.

  1. Cat.No. 产品名称 Information
  2. GP26143 CTSZ Mouse, Active CTSZ Mouse Recombinant produced in Baculovirus is a single, glycosylated, polypeptide chain containing 292 amino acids (23-306 aa) and having a molecular mass of32
  3. GP26142 CTSF Human, Sf9 CTSF produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 474 amino acids (20-484
  4. GC68008 GÜ2602
  5. GC65998 Cathepsin C-IN-5
  6. GC65432 LV-320
  7. GC65307 S130
  8. GC65153 KGP94
  9. GC63856 Relacatib
  10. GC62889 Cathepsin D and E FRET Substrate acetate
  11. GC62634 GSK-2793660
  12. GC62302 Cysteine protease inhibitor-2
  13. GC61791 SID 26681509 quarterhydrate
  14. GC46885 Asperglaucide An amide with diverse biological activities
  15. GC61158 ONO-5334
  16. GC60960 JPM-OEt
  17. GC60212 K777 A cysteine protease inhibitor
  18. GC38809 LHVS
  19. GA23863 Z-Leu-Val-Gly-diazomethylketone Z-Leu-Val-Gly-diazomethylketone 是一种可渗透细胞且不可逆的半胱氨酸蛋白酶抑制剂。
  20. GA23177 Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH₂ Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH₂ 是组织蛋白酶 D 和 E 而不是 B、H 或 L 的荧光底物。
  21. GC35111 3-Epiursolic Acid A pentacyclic triterpenoid with diverse biological activities
  22. GC40769 Asperphenamate A fungal secondary metabolite
  23. GC40694 Calpain Inhibitor II A non-selective cysteine protease inhibitor
  24. GC34924 NSC 185058 An inhibitor of ATG4B
  25. GC34682 N-Ethylmaleimide A modifier of protein sulfhydryl groups
  26. GC19520 Cysteine Protease inhibitor 半胱氨酸蛋白酶抑制剂是半胱氨酸蛋白酶的抑制剂。
  27. GC33892 Cathepsin Inhibitor 2
  28. GC33829 Papain 木瓜蛋白酶(Papain)是一种具有广泛特异性的半胱氨酸蛋白酶,可切割碱性氨基酸、亮氨酸或甘氨酸的肽键。
  29. GC32873 VBY-825
  30. GC31856 Petesicatib
  31. GC31465 L-873724
  32. GC11553 2-cyano-Pyrimidine A cathepsin K inhibitor
  33. GC15708 Cysteine Protease inhibitor hydrochloride Cysteine Protease inhibitor hydrochloride 是半胱氨酸蛋白酶的抑制剂。
  34. GC16181 Cathepsin Inhibitor 1 Cathepsin inhibitor 1 (compound 25) 是一种有效的选择性 Cathepsin 抑制剂,对 CatL、CatL2、CatS、CatK 和 CatB 的 pIC50 分别为 7.9、6.7、6.0、5.5 和 5.2。
  35. GC12751 Balicatib A cathepsin K inhibitor
  36. GC16388 Odanacatib (MK-0822) A potent, selective, and neutral inhibitor of cathepsin K
  37. GC15917 CA-074 Me A cathepsin B and L inhibitor
  38. GC10377 SID 26681509 SID 26681509 是一种有效的、可逆的、竞争性的、选择性的人组织蛋白酶 L 抑制剂,IC50 为 56 nM。
  39. GC11640 MDL 28170 A cell permeable, selective calpain inhibitor
  40. GC17989 L 006235 An inibitor of cathepsin K
  41. GC10342 Calpeptin A calpain inhibitor
  42. GC14903 Cathepsin S inhibitor A potent cathepsin S inhibitor
  43. GC10376 Cathepsin G Inhibitor I

    Cathepsin G Inhibitor I 是一种有效的、选择性的、可逆的、竞争性的、非肽的组织蛋白酶 G 抑制剂。

  44. GC16505 E-64-c An active metabolite of E-64d
  45. GC16317 CA 074 A selective cathepsin B inhibitor
  46. GC13787 E 64d

    A protease inhibitor

  47. GC10477 PMSF A nonspecific, irreversible serine protease inhibitor
  48. GC13418 E-64 A fungal metabolite with diverse biological activities
  49. GC10027 Leupeptin, Microbial A reversible protease inhibitor

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