Cathepsin(组织蛋白酶)
Cathepsins (the term standing for “lysosomal proteolytic enzyme”) are a class of globular proteases that catalyze the hydrolysis of intracellular peptides and also exhibit extracellular functions. So far, a total of sixteen members of human cathepsin family have been identified, which are divided into three subfamilies, including cysteine protease family (cathepsin B, C, F, H, L, K, O, S, V, W, X and Z), serine carboxypeptidase family (cathepsin A and G) and aspartic protease family (cathepsin D and E). Cathepsins are highly expressed in various human cancers with each member playing different roles in distinct tumorigenic processes, including proliferation, angiogenesis, metastasis and invasion.
- Cat.No. 产品名称 Information
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GP26143
CTSZ Mouse, Active
CTSZ Mouse Recombinant produced in Baculovirus is a single, glycosylated, polypeptide chain containing 292 amino acids (23-306 aa) and having a molecular mass of32
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GP26142
CTSF Human, Sf9
CTSF produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 474 amino acids (20-484
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GC68008
GÜ2602
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GC65998
Cathepsin C-IN-5
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GC65432
LV-320
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GC65307
S130
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GC65153
KGP94
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GC63856
Relacatib
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GC62889
Cathepsin D and E FRET Substrate acetate
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GC62634
GSK-2793660
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GC62302
Cysteine protease inhibitor-2
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GC61791
SID 26681509 quarterhydrate
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GC46885
Asperglaucide
An amide with diverse biological activities
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GC61158
ONO-5334
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GC60960
JPM-OEt
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GC60212
K777
A cysteine protease inhibitor
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GC38809
LHVS
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GA23863
Z-Leu-Val-Gly-diazomethylketone
Z-Leu-Val-Gly-diazomethylketone 是一种可渗透细胞且不可逆的半胱氨酸蛋白酶抑制剂。
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GA23177
Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH₂
Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH₂ 是组织蛋白酶 D 和 E 而不是 B、H 或 L 的荧光底物。
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GC35111
3-Epiursolic Acid
A pentacyclic triterpenoid with diverse biological activities
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GC40769
Asperphenamate
A fungal secondary metabolite
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GC40694
Calpain Inhibitor II
A non-selective cysteine protease inhibitor
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GC34924
NSC 185058
An inhibitor of ATG4B
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GC34682
N-Ethylmaleimide
A modifier of protein sulfhydryl groups
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GC19520
Cysteine Protease inhibitor
半胱氨酸蛋白酶抑制剂是半胱氨酸蛋白酶的抑制剂。
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GC33892
Cathepsin Inhibitor 2
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GC33829
Papain
木瓜蛋白酶(Papain)是一种具有广泛特异性的半胱氨酸蛋白酶,可切割碱性氨基酸、亮氨酸或甘氨酸的肽键。
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GC32873
VBY-825
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GC31856
Petesicatib
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GC31465
L-873724
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GC11553
2-cyano-Pyrimidine
A cathepsin K inhibitor
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GC15708
Cysteine Protease inhibitor hydrochloride
Cysteine Protease inhibitor hydrochloride 是半胱氨酸蛋白酶的抑制剂。
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GC16181
Cathepsin Inhibitor 1
Cathepsin inhibitor 1 (compound 25) 是一种有效的选择性 Cathepsin 抑制剂,对 CatL、CatL2、CatS、CatK 和 CatB 的 pIC50 分别为 7.9、6.7、6.0、5.5 和 5.2。
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GC12751
Balicatib
A cathepsin K inhibitor
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GC16388
Odanacatib (MK-0822)
A potent, selective, and neutral inhibitor of cathepsin K
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GC15917
CA-074 Me
A cathepsin B and L inhibitor
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GC10377
SID 26681509
SID 26681509 是一种有效的、可逆的、竞争性的、选择性的人组织蛋白酶 L 抑制剂,IC50 为 56 nM。
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GC11640
MDL 28170
A cell permeable, selective calpain inhibitor
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GC17989
L 006235
An inibitor of cathepsin K
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GC10342
Calpeptin
A calpain inhibitor
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GC14903
Cathepsin S inhibitor
A potent cathepsin S inhibitor
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GC10376
Cathepsin G Inhibitor I
Cathepsin G Inhibitor I 是一种有效的、选择性的、可逆的、竞争性的、非肽的组织蛋白酶 G 抑制剂。
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GC16505
E-64-c
An active metabolite of E-64d
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GC16317
CA 074
A selective cathepsin B inhibitor
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GC13787
E 64d
A protease inhibitor
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GC10477
PMSF
A nonspecific, irreversible serine protease inhibitor
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GC13418
E-64
A fungal metabolite with diverse biological activities
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GC10027
Leupeptin, Microbial
A reversible protease inhibitor