Home >> Signaling Pathways >> GPCR/G protein

GPCR/G protein(G 蛋白偶联受体/G 蛋白)

  1. Cat.No. 产品名称 Information
  2. GC26069 WAY-639889 WAY-639889 is a bioactive compound relative to neuropeptide Y-5.
  3. GC26027 V-0219 V-0219 is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), can be used for obesity-associated diabetes research.
  4. GC26016 TSHR antagonist S37 TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).
  5. GC26002 Trazodone Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.
  6. GC25898 SB 200646 SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo.
  7. GC25786 Propafenone Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.
  8. GC25756 Pirenperone Pirenperone (R-47456, R-50656), a quinazoline derivative, is a selective antagonist of SR-2A (5-HT2 serotonin receptor) when employed in low doses. Pirenperone behaves like a typical neuroleptic when used in higher doses (greater than 0.1 mg/kg).
  9. GC25728 PF-4136309 PF-4136309 (INCB8761, PF-04136309) is a potent, selective, and orally bioavailable CCR2 antagonist with an IC50 of 5.2 nM for human CCR2.
  10. GC25663 Nebivolol Nebivolol (Bystolic,R 065824) is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.
  11. GC25618 Maropitant citrate Maropitant citrate is a novel neurokinin type-1 (NK1) receptor antagonist with anti-inflammatory and analgesic properties
  12. GC25569 Lerisetron Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
  13. GC25563 Lasmiditan succinate Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
  14. GC25484 Guanabenz Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action.
  15. GC25434 Frovatriptan Succinate Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
  16. GC25412 Fenoterol Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.
  17. GC25385 Esmolol Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.
  18. GC25259 Cisapride hydrate Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
  19. GC25253 Cinitapride Hydrogen Tartrate Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
  20. GC25197 Carvedilol EP IMpurity E Carvedilol is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF).
  21. GC25140 Bisoprolol Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension.
  22. GC25120 Balixafortide (POL6326) Balixafortide (POL6326) is an orally bioavailable peptidic CXC chemokine receptor 4 (CXCR4) antagonist
  23. GC25051 Alloxazine Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.
  24. GC25046 Albiglutide Fragment Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).
  25. GC67989 (S)-Mirtazapine
  26. GC67982 Treprostinil palmitil
  27. GC67979 MK-6884
  28. GC67977 Lubabegron
  29. GC67974 L-Glutamine-15N2
  30. GC67972 S-777469
  31. GC67957 Orexin A (human, rat, mouse) (acetate)
  32. GC67937 (R)-Mirtazapine
  33. GC67929 Orexin 2 Receptor Agonist 2
  34. GC67923 Renzapride
  35. GC67897 CCR8 antagonist 2
  36. GC67893 Sigma-LIGAND-1 hydrochloride
  37. GC67882 VU6028418
  38. GC67869 RPT193
  39. GC67795 P2Y2R/GPR17 antagonist 1
  40. GC67788 CCR6 antagonist 1
  41. GC67786 THX-B
  42. GC67768 TRV055 hydrochloride
  43. GC67726 ONO-8711 dicyclohexylamine
  44. GC67715 Upidosin
  45. GC67702 Abanoquil
  46. GC67692 Bufuralol
  47. GC67691 Midaglizole
  48. GC67683 Romifidine
  49. GC67681 (αR,8aS)-GSK1614343
  50. GC67620 Methacholine bromide
  51. GC66678 2-(3-Trifluoromethylphenyl)glycine hydrochloride

Items 1 to 50 of 2991 total

per page
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Set Descending Direction