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Home >> Signaling Pathways >> GPCR/G protein >> CXCR

CXCR(CXC趋化因子受体)

CXCR (CXC chemokine receptor) is a group of receptors that belong to GPCRs and specifically binds and responds to cytokines of the CXC chemokine family.

  1. Cat.No. 产品名称 Information
  2. GC25120 Balixafortide (POL6326) Balixafortide (POL6326) is an orally bioavailable peptidic CXC chemokine receptor 4 (CXCR4) antagonist
  3. GC68040 MSX-127
  4. GC66332 Eldelumab
  5. GC65908 CXCR2 antagonist 2
  6. GC65476 CXCR7 antagonist-1 hydrochloride
  7. GC64312 AZD4721
  8. GC64090 Corydalmine
  9. GC63411 CXCR7 antagonist-1
  10. GC62588 (R,R)-CXCR2-IN-2
  11. GC62475 CXCR2-IN-2
  12. GC62296 Ladarixin sodium
  13. GC62256 Ladarixin
  14. GC61219 PS372424 hydrochloride
  15. GC50230 SB 332235 A CXCR2 antagonist
  16. GC38541 ATI-2341 TFA ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.
  17. GC38217 VUF11207 fumarate
  18. GC38204 SX-682 SX-682 is an orally bioavailable small-molecule allosteric inhibitor of CXCR1 and CXCR2 that blocks tumor MDSC recruitment and enhances T cell activation and antitumor immunity.
  19. GC37724 TAK-779 An antagonist of CCR5, CXCR3, and CCR2b
  20. GC37605 SCH 546738
  21. GC37022 PS372424
  22. GC36737 Nicotinamide N-oxide A metabolite of nicotinamide
  23. GC36704 NBI-74330 A CXCR3 antagonist
  24. GC36550 Mavorixafor trihydrochloride A CXCR4 antagonist
  25. GC36411 Kynurenic acid sodium Kynurenic acid sodium 是一种内源性色氨酸代谢物，是针对靶点 NMDA, glutamate, α7 nicotinic acetylcholine receptor 的光谱性拮抗剂。Kynurenic acid sodium 也是 GPR35/CXCR8 的激动剂。
  26. GC36350 IT1t A CXCR4 antagonist
  27. GC36184 GPR35 agonist 1
  28. GC36033 FC131 TFA An inhibitor of CXCR4 activation
  29. GC35763 CXCR7 modulator 1
  30. GC42817 Antileukinate A CXCR2 chemokine receptor antagonist
  31. GC34386 ALX 40-4C Trifluoroacetate
  32. GC34339 CXCR7 modulator 2
  33. GC19486 LIT-927 A neutraligand of CXCL12
  34. GC33413 USL311
  35. GC32707 AZD-5069 A CXCR2 antagonist
  36. GC32208 ALX 40-4C
  37. GC31763 E6130
  38. GC31754 CXCR2-IN-1
  39. GC31653 AZD8797
  40. GC30625 Burixafor hydrobromide (TG-0054 hydrobromide)
  41. GC19255 MSX-122 A partial antagonist of CXCR4
  42. GC19230 LY2510924 LY2510924 是一种有效的选择性 CXCR4 拮抗剂；阻断 SDF-1 与 CXCR4 的结合，IC50 为 0.079 nM。
  43. GC19116 Danirixin A CXCR2 antagonist
  44. GC17526 BKT140 A CXCR4 antagonist
  45. GC14711 ATI-2341 A Gαi-signaling biased CXCR4 agonist
  46. GC17538 UNBS 5162 A antagonist of CXCL chemokine expression
  47. GC16465 SB 225002 Selective CXCR2 antagonist
  48. GC13458 SB 265610 A selective CXCR2 inverse agonist
  49. GC10432 IT1t dihydrochloride A CXCR4 antagonist
  50. GC17174 ML 145 An antagonist of GPR35
  51. GC12909 Zaprinast A cGMP phosphodiesterase inhibitor

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