Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. Product Name Information
GC10419 (R)-CCG-1423 Rho inhibitor
GC16429 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive
GC14497 (S)-CCG-1423 Rho inhibitor
GC34999 (S)-Ceralasertib (S)-Ceralasertib 从专利 WO2011154737A1 中获取，化合物 II，IC50 为 2.578 nM。(S)-Ceralasertib 是一种有效的选择性亚砜亚胺吗啉代嘧啶 ATR 抑制剂，具有优异的临床前物化和药代动力学 (PK) 特征。(S)-Ceralasertib 水溶性改善，并且消除 CYP3A4 时间依赖性抑制。
GC41737 (S)-Glycyl-H-1152 (hydrochloride) Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability.
GC12954 10-DAB (10-Deacetylbaccatin)
Precursor of antitumor compound Palitaxel and Docetaxel
GC35044 10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyl paclitaxel是Paclitaxel的衍生物，相比Paclitaxel，具有更好的药学活性和水溶性。
GC35045 10-Oxo Docetaxel 10-Oxo Docetaxel (Docetaxel Impurity 1) 是新型紫杉烷，具有明显的抗肿瘤活性，是多西他赛（docetaxel）的中间体。
GC17295 10058-F4 C-Myc-Max dimerization inhibitor
GC14918 10074-G5 c-Myc inhibitor
GC15084 2-Methoxyestradiol (2-MeOE2)
Apoptotic, antiproliferative and antiangiogenic agent
GC12314 3-(4-Pyridyl)indole ROCK-I inhibitor
GC15389 360A
G-quadruplex structures inhibitor
GC10115 360A iodide G-quadruplex structures inhibitor
GC14186 3MB-PP1 polo-like kinase 1 (Plk1) allele inhibitor,ATP-competitive
GC17271 4'-Demethylepipodophyllotoxin Anti-cancer drug
GC15478 6H05 K-Ras inhibitor
GC35188 7-Epi-10-oxo-docetaxel 7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) 是多西他赛（docetaxel）的杂质。
GC35189 7-Epi-docetaxel 7-Epi-10-oxo-docetaxel (Docetaxel Impurity C; 7-Epitaxotere)是多西他赛（docetaxel）的杂质。
GN10625 7-Epitaxol Extracted from Taxus brevifolia;Store the product in sealed, cool and dry condition