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Home >> Signaling Pathways >> Cell Cycle/Checkpoint

Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for  Cell Cycle/Checkpoint

  1. Cat.No. 产品名称 Information
  2. GC25940 SNS-314 SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.
  3. GC25482 GSK269962A HCl GSK269962A HCl (GSK269962B, GSK269962) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
  4. GC25372 Elimusertib (BAY-1895344) hydrochloride Elimusertib (BAY-1895344) hydrochloride is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.
  5. GC25075 Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222) Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM.
  6. GC25025 Abraxane Abraxane (Nab-Paclitaxel), a novel solvent-free taxane with the binding ratio of Paclitaxel to human serum albumin of 1:9, is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimer and inhibits microtubule depolymerization to stabilize the microtubule system.
  7. GC67900 AMXI-5001 hydrochloride
  8. GC67899 Aurora kinase inhibitor-8
  9. GC67888 RAD51-IN-5
  10. GC52513 Indolimine-214 A genotoxic gut microbiota metabolite
  11. GC52499 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) A sensitive substrate for neutrophil elastase
  12. GC52489 Ceramide (hydroxy) (bovine spinal cord) A sphingolipid
  13. GC52486 Ceramide Phosphoethanolamine (bovine) A sphingolipid
  14. GC52485 Ceramide (non-hydroxy) (bovine spinal cord) A sphingolipid
  15. GC52484 Purified Ganglioside Mixture (bovine) (ammonium salt) A mixture of purified bovine gangliosides
  16. GC52474 Arg-Gly-Asp (trifluoroacetate salt) A synthetic peptide corresponding to an integrin cell adhesion sequence
  17. GC52472 Inostamycin A (sodium salt) A bacterial metabolite with anticancer activity
  18. GC52447 Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt) A fluorogenic substrate for the 20S proteasome and calpains
  19. GC52389 Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A synthetic peptide fragment of caveolin-1
  20. GC52372 Ac-VDVAD-AFC (trifluoroacetate salt) A fluorogenic substrate for caspase-2
  21. GC52371 Vimentin (G146R) (139-159)-biotin Peptide A biotinylated mutant vimentin peptide
  22. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide
  23. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide
  24. GC52365 4-tert-Octylphenol monoethoxylate An alkylphenolethoxylate and a degradation product of non-ionic surfactants
  25. GC52364 Vimentin (139-159)-biotin Peptide A biotinylated vimentin peptide
  26. GC52360 Chymotrypsin Substrate I, Colorimetric (trifluoroacetate salt) A colorimetric chymotrypsin substrate
  27. GC52358 Malachite Green (chloride) A triphenylmethane dye
  28. GC52332 Arimoclomol A co-inducer of heat shock proteins
  29. GC52293 STAT3 Inhibitor 4m A STAT3 inhibitor
  30. GC52288 Fumonisin B1-13C34 An internal standard for the quantification of fumonisin B1
  31. GC52245 CAY10792 An anticancer agent
  32. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols
  33. GC67333 Estramustine
  34. GC66457 MY-875
  35. GC66437 SB-216
  36. GC66338 ROCK1-IN-1 WAY-624704 is a novel Rho kinases (ROCK) inhibitor with an Ki of 17 nM.
  37. GC66242 Flutax-2 (5/6-mixture)
  38. GC66198 Anti-α-Tubulin Antibody, AF555 conjugate
  39. GC66056 Dynole 2-24
  40. GC66050 Rho-Kinase-IN-2
  41. GC66036 AZ13705339 hemihydrate
  42. GC65994 WEE1-IN-5 Debio 0123 is an inhibitor of Wee1 kinase which is a key regulator of the G2/M and S phase checkpoints.
  43. GC65935 CAM833
  44. GC65897 OXi8007
  45. GC65887 SOP1812
  46. GC52196 RGD Peptide An inhibitor of integrin-ligand interactions
  47. GC52192 (S)-4'-nitro-Blebbistatin A more stable and less phototoxic form of (–)-blebbistatin
  48. GC52140 2-Methoxyhydroquinone A phenolic compound
  49. GC52129 3-Amino-5-hydroxybenzoic Acid A biosynthetic precursor to ansamycin antibiotics
  50. GC52126 8-chloro Caffeine A derivative of caffeine
  51. GC65578 Aminobenzenesulfonic auristatin E TFA

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