Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more
Products for Cell Cycle/Checkpoint
- ATM/ATR(26)
- Aurora Kinase(49)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(20)
- CRM1(8)
- Cyclin-Dependent Kinases(69)
- E1 enzyme(1)
- G-quadruplex(10)
- Haspin(5)
- HMTase(1)
- Kinesin(23)
- Ksp(4)
- Microtubule/Tubulin(206)
- Mps1(13)
- Mitotic(7)
- RAD51(12)
- ROCK(57)
- Rho(13)
- PERK(8)
- PLK(33)
- PTEN(6)
- Wee1(6)
- PAK(20)
- Arp2/3 Complex(8)
- Dynamin(9)
- ECM & Adhesion Molecules(40)
- Cytoskeleton & Motor Proteins(53)
- Endomembrane System & Vesicular Trafficking(26)
- G1(38)
- Genotoxic Stress(18)
- G2/M(26)
- G2/S(10)
- Inositol Phosphates(18)
- Proteolysis(98)
- Cellular Chaperones(8)
- Cat.No. 产品名称 Information
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GC25940
SNS-314
SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.
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GC25482
GSK269962A HCl
GSK269962A HCl (GSK269962B, GSK269962) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
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GC25372
Elimusertib (BAY-1895344) hydrochloride
Elimusertib (BAY-1895344) hydrochloride is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.
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GC25075
Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)
Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM.
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GC25025
Abraxane
Abraxane (Nab-Paclitaxel), a novel solvent-free taxane with the binding ratio of Paclitaxel to human serum albumin of 1:9, is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimer and inhibits microtubule depolymerization to stabilize the microtubule system.
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GC67900
AMXI-5001 hydrochloride
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GC67899
Aurora kinase inhibitor-8
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GC67888
RAD51-IN-5
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GC52513
Indolimine-214
A genotoxic gut microbiota metabolite
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GC52499
Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt)
A sensitive substrate for neutrophil elastase
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GC52489
Ceramide (hydroxy) (bovine spinal cord)
A sphingolipid
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GC52486
Ceramide Phosphoethanolamine (bovine)
A sphingolipid
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GC52485
Ceramide (non-hydroxy) (bovine spinal cord)
A sphingolipid
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GC52484
Purified Ganglioside Mixture (bovine) (ammonium salt)
A mixture of purified bovine gangliosides
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GC52474
Arg-Gly-Asp (trifluoroacetate salt)
A synthetic peptide corresponding to an integrin cell adhesion sequence
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GC52472
Inostamycin A (sodium salt)
A bacterial metabolite with anticancer activity
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GC52447
Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt)
A fluorogenic substrate for the 20S proteasome and calpains
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GC52389
Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
A synthetic peptide fragment of caveolin-1
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GC52372
Ac-VDVAD-AFC (trifluoroacetate salt)
A fluorogenic substrate for caspase-2
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GC52371
Vimentin (G146R) (139-159)-biotin Peptide
A biotinylated mutant vimentin peptide
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GC52370
Citrullinated Vimentin (R144) (139-159)-biotin Peptide
A biotinylated and citrullinated vimentin peptide
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GC52367
Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide
A biotinylated and citrullinated mutant vimentin peptide
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GC52365
4-tert-Octylphenol monoethoxylate
An alkylphenolethoxylate and a degradation product of non-ionic surfactants
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GC52364
Vimentin (139-159)-biotin Peptide
A biotinylated vimentin peptide
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GC52360
Chymotrypsin Substrate I, Colorimetric (trifluoroacetate salt)
A colorimetric chymotrypsin substrate
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GC52358
Malachite Green (chloride)
A triphenylmethane dye
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GC52332
Arimoclomol
A co-inducer of heat shock proteins
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GC52293
STAT3 Inhibitor 4m
A STAT3 inhibitor
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GC52288
Fumonisin B1-13C34
An internal standard for the quantification of fumonisin B1
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GC52245
CAY10792
An anticancer agent
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GC52227
5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone
An active metabolite of various polyphenols
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GC67333
Estramustine
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GC66457
MY-875
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GC66437
SB-216
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GC66338
ROCK1-IN-1
WAY-624704 is a novel Rho kinases (ROCK) inhibitor with an Ki of 17 nM.
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GC66242
Flutax-2 (5/6-mixture)
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GC66198
Anti-α-Tubulin Antibody, AF555 conjugate
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GC66056
Dynole 2-24
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GC66050
Rho-Kinase-IN-2
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GC66036
AZ13705339 hemihydrate
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GC65994
WEE1-IN-5
Debio 0123 is an inhibitor of Wee1 kinase which is a key regulator of the G2/M and S phase checkpoints.
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GC65935
CAM833
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GC65897
OXi8007
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GC65887
SOP1812
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GC52196
RGD Peptide
An inhibitor of integrin-ligand interactions
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GC52192
(S)-4'-nitro-Blebbistatin
A more stable and less phototoxic form of (–)-blebbistatin
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GC52140
2-Methoxyhydroquinone
A phenolic compound
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GC52129
3-Amino-5-hydroxybenzoic Acid
A biosynthetic precursor to ansamycin antibiotics
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GC52126
8-chloro Caffeine
A derivative of caffeine
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GC65578
Aminobenzenesulfonic auristatin E TFA