Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. Product Name Information
GC40702 α-D-Galactopyranosylphenyl isothiocyanate
α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.
GC41676 (±)-Nornicotine (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist.
GC49482 (±)-Nornicotine-d4 An internal standard for the quantification of (±)-nornicotine
GC41684 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups.
GC40802 (±)12(13)-DiHOME
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol 2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system.
GC45890 (+)-Abscisic Acid-d6
GC62728 (1E)-CFI-400437 dihydrochloride (1E)-CFI-400437 dihydrochloride 是一种有效的 PLK4 (IC50= 0.6 nM)，并对 PLK 家族的其他成员有选择性 (>10 μM)。(1E)-CFI-400437 dihydrochloride 抑制 Aurora A、 Aurora B、 KDR 和 FLT-3，IC50 分别为 0.37、0.21、0.48 和 0.18 μM。具有抗增殖活性。
GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase.
GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe.
GC46335 (E)-Fenpyroximate
GC10419 (R)-CCG-1423 Rho inhibitor
GC16429 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive
GC41719 (R)-nitro-Blebbistatin (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin.
GC46347 (S)-(+)-Methoprene
GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
GC14497 (S)-CCG-1423 Rho inhibitor
GC34999 (S)-Ceralasertib (S)-Ceralasertib 从专利 WO2011154737A1 中获取，化合物 II，IC50 为 2.578 nM。(S)-Ceralasertib 是一种有效的选择性亚砜亚胺吗啉代嘧啶 ATR 抑制剂，具有优异的临床前物化和药代动力学 (PK) 特征。(S)-Ceralasertib 水溶性改善，并且消除 CYP3A4 时间依赖性抑制。
GC46351 (S)-CR8
GC41737 (S)-Glycyl-H-1152 (hydrochloride) Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability.
GC40145 (S)-Laudanosine (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium.
GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases.
GC18275 1,2-Dihexadecyl-sn-glycero-3-PC 1,2-Dihexadecyl-sn-glycero-3-PC is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions.
GC45783 1,2-Dioleoyl-rac-glycerol-13C3
GC46379 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)
GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid.
GC46385 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose
GC19528 1,4-Benzoquinone
GC18726 1-Methyl-1,4-dihydronicotinamide 1-Methyl-1,4-dihydronicotinamide is a derivative of nicotinamide .
GC49736 10-acetyl Docetaxel A derivative of paclitaxel and an inhibitor of microtubule depolymerization
GC12954 10-DAB (10-Deacetylbaccatin)
Precursor of antitumor compound Palitaxel and Docetaxel
GC35044 10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyl paclitaxel是Paclitaxel的衍生物，相比Paclitaxel，具有更好的药学活性和水溶性。
GC35045 10-Oxo Docetaxel 10-Oxo Docetaxel (Docetaxel Impurity 1) 是新型紫杉烷，具有明显的抗肿瘤活性，是多西他赛（docetaxel）的中间体。
GC17295 10058-F4 C-Myc-Max dimerization inhibitor
GC63576 10074-A4 10074-A4 是一种 c-Myc 抑制剂，可以在肽链的不同位点与 c-Myc370-409 结合。10074-A4 具有抗癌作用。
GC14918 10074-G5 c-Myc inhibitor
GC40448 12(S)-HETE
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.
GC46434 13C15-Nivalenol
GC49390 13C6-4-Nitroaniline An internal standard for the quantification of 4-nitroaniline
GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N.
GC48423 19-O-Acetylchaetoglobosin A
GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) 2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.
GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone 2,3-Dimethoxy-5-methyl-p-benzoquinone, also known as coenzyme Q0, is a key intermediate in the synthesis of coenzyme Q, coenzyme Q10, other ubiquinones, and vitamin E.
GC45324 2,5-dimethyl Celecoxib
GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline A food-derived carcinogen
GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.
GC15084 2-Methoxyestradiol (2-MeOE2) Apoptotic, antiproliferative and antiangiogenic agent
GC42161 2H-Cho-Arg (trifluoroacetate salt) 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.
GC40618 3',4',7-Trihydroxyisoflavone 3',4',7-Trihydroxyisoflavone is a natural isoflavonoid that has antioxidant activity.