Rho

Rho GTPases act as molecular switches that convert and amplify external signals into cellular effects upon activation of cell surface receptor in various signaling transduction pathway. It functions in cell proliferation, motility, survival cytoskeletal remodeling and membrane trafficking etc.

Cat.No. 产品名称 Information
GC14497 (S)-CCG-1423 A stereoisomer of CCG-1423, a Rho inhibitor
GC10419 (R)-CCG-1423 A stereoisomer of CCG-1423, a Rho inhibitor
GC14986 CCG-100602 A Rho/MKL1 transcriptional pathway inhibitor
GC12795 CCG-1423 An inhibitor of Rho-mediated cell signalling
GC12817 K–115 hydrochloride dihydrate K-115 hydrochloride dihydrate (K-115) 是 ROCK 的特异性抑制剂，对 ROCK2 和 ROCK1 的 IC50 分别为 19 和 51 nM。
GC15478 6H05 An allosteric inhibitor of oncogenic K-Ras(G12C)
GC11754 AS 1892802 A ROCK1 and ROCK2 inhibitor
GC15170 SB 772077B dihydrochloride A ROCK1 and ROCK2 inhibitor
GC17388 K-Ras(G12C) inhibitor 6 K-Ras(G12C) inhibitor 6 是一种不可逆的 K-Ras(G12C) 变构抑制剂。
GC10030 EHop-016 A Rac1 and Rac3 inhibitor
GC12470 ZCL278 A selective Cdc42 inhibitor
GC10069 NSC 23766 trihydrochloride Inhibitor of Rac1
GC14701 Zoledronic Acid A bisphosphonate that inhibits bone resorption