Stem Cell(干细胞)
- CK1(5)
- EZH2(8)
- GSK-3(58)
- HSC(6)
- iPSC(6)
- Hedgehog(37)
- Notch(31)
- Smoothened(34)
- Wnt/β-catenin(109)
- Hippo Signaling(4)
- Cancer stem cell(23)
- MST1/2(1)
- ESC(1)
- Oct3/4(5)
- Porcupine(6)
- YAP(17)
- Casein Kinase(39)
- Cat.No. 产品名称 Information
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GC26088
YAP-TEAD Inhibitor 1 (Peptide 17)
YAP-TEAD Inhibitor 1 (Peptide 17) is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM.
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GC26049
WAY-119064
WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.
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GC25838
RBPJ Inhibitor-1 (RIN1)
RBPJ Inhibitor-1 (RIN1) is a potent inhibitor of the transcription factor RBPJ that disrupts the interaction between NOTCH and RBPJ.
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GC25603
M2912
M2912 (MSC2504877) is a very potent TNKS1/TNKS2 inhibitor (IC50=0.6 nM for TNKS1) with exquisite selectivity over other PARP family enzymes and favorable compound properties. This inhibitor potently modulates the Wnt/β-catenin pathway by elevating the levels of axin2 (EC50=17 nM) and tankyrase in DLD1 cells in a dose-dependent manner resulting in reduced cellular Wnt reporter activity.
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GC67775
Casein kinase 1δ-IN-3
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GC67737
NLS-StAx-h TFA
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GC52376
BMP2-derived Peptide (trifluoroacetate salt)
A synthetic peptide
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GC66390
3-epi-Vitamin D3
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GC66371
(E)-Ferulic acid-d3
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GC66039
Wnt/β-catenin agonist 3
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GC66035
GSK3-IN-1
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GC66033
Casein kinase 1δ-IN-1
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GC66032
GSK-3β inhibitor 11
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GC65993
MSC-4106
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GC65919
NRX-252114
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GC65916
NRX-103095
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GC65889
TDI-011536
TDI-011536 is a potent Lats kinase inhibitor that interrupts Hippo-Yap signaling and promotes proliferation of lesioned cardiac muscle cells.
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GC65375
Phospho-Glycogen Synthase Peptide-2(substrate) TFA
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GC65356
KY-02327 acetate
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GC65336
NRX-252262
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GC65185
TEAD-IN-2
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GC65167
Carboxylesterase-IN-3
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GC65165
Carboxylesterase-IN-2
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GC65131
YAP/TAZ inhibitor-2
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GC65116
GA-017
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10±0.79 and 3.92±0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58±0.11 and 0.25±0.03 nM, respectively.
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GC65066
Prodigiosin hydrochloride
A natural red pigment and antibiotic
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GC64922
Rovalpituzumab
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GC64837
Nefopam D3 hydrochloride
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GC64832
NRX-2663
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GC64816
Coronaridine
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GC64638
ALV1
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GC64536
Notch 1 TFA
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GC64419
MRT-14
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GC64382
SGC-CK2-1
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GC49827
5-Androstenetriol
An active metabolite of DHEA
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GC64378
Valproic acid-d6
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GC64134
Hh-Ag1.5
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GC64131
TMX-4116
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GC64005
FPFT-2216
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GC63863
MRT-83 hydrochloride
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GC49687
Goralatide (acetate)
A tetrapeptide regulator of hematopoiesis
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GC49667
PD 168568 (hydrochloride)
A dopamine D4 receptor antagonist
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GC49651
19-alkyne Cholesterol
An alkyne derivative of cholesterol for click chemistry
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GC63695
Wnt/β-catenin agonist 2
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GC63560
ZW4864
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GC63559
ZW4864 free base
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GC63465
KY-02327
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GC63463
Casein Kinase inhibitor A86
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GC63446
PF-04802367
PF-04802367 (PF-367) is a highly selective Glycogen synthase kinase-3 (GSK-3) inhibitor with IC50s of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.
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GC63336
MRT-81
MRT-81 is a potent antagonist of human and rodent smoothened (Smo) receptors, with an IC50 value of 41 nM in the Shh-light2 cells, exerting potent hedgehog (Hh) signaling pathway inhibiting activity.