Stem Cell(干细胞)

Cat.No. 产品名称 Information

GC26088 YAP-TEAD Inhibitor 1 (Peptide 17) YAP-TEAD Inhibitor 1 (Peptide 17) is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM.

GC26049 WAY-119064 WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.

GC25838 RBPJ Inhibitor-1 (RIN1) RBPJ Inhibitor-1 (RIN1) is a potent inhibitor of the transcription factor RBPJ that disrupts the interaction between NOTCH and RBPJ.

GC25603 M2912 M2912 (MSC2504877) is a very potent TNKS1/TNKS2 inhibitor (IC50=0.6 nM for TNKS1) with exquisite selectivity over other PARP family enzymes and favorable compound properties. This inhibitor potently modulates the Wnt/β-catenin pathway by elevating the levels of axin2 (EC50=17 nM) and tankyrase in DLD1 cells in a dose-dependent manner resulting in reduced cellular Wnt reporter activity.

GC67775 Casein kinase 1δ-IN-3

GC67737 NLS-StAx-h TFA

GC52376 BMP2-derived Peptide (trifluoroacetate salt) A synthetic peptide

GC66390 3-epi-Vitamin D3

GC66371 (E)-Ferulic acid-d3

GC66039 Wnt/β-catenin agonist 3

GC66035 GSK3-IN-1

GC66033 Casein kinase 1δ-IN-1

GC66032 GSK-3β inhibitor 11

GC65993 MSC-4106

GC65919 NRX-252114

GC65916 NRX-103095

GC65889 TDI-011536 TDI-011536 is a potent Lats kinase inhibitor that interrupts Hippo-Yap signaling and promotes proliferation of lesioned cardiac muscle cells.

GC65375 Phospho-Glycogen Synthase Peptide-2(substrate) TFA

GC65356 KY-02327 acetate

GC65336 NRX-252262

GC65185 TEAD-IN-2

GC65167 Carboxylesterase-IN-3

GC65165 Carboxylesterase-IN-2

GC65131 YAP/TAZ inhibitor-2

GC65116 GA-017 GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10±0.79 and 3.92±0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58±0.11 and 0.25±0.03 nM, respectively.

GC65066 Prodigiosin hydrochloride A natural red pigment and antibiotic

GC64922 Rovalpituzumab

GC64837 Nefopam D3 hydrochloride

GC64832 NRX-2663

GC64816 Coronaridine

GC64638 ALV1

GC64536 Notch 1 TFA

GC64419 MRT-14

GC64382 SGC-CK2-1

GC49827 5-Androstenetriol An active metabolite of DHEA

GC64378 Valproic acid-d6

GC64134 Hh-Ag1.5

GC64131 TMX-4116

GC64005 FPFT-2216

GC63863 MRT-83 hydrochloride

GC49687 Goralatide (acetate) A tetrapeptide regulator of hematopoiesis

GC49667 PD 168568 (hydrochloride) A dopamine D₄ receptor antagonist

GC49651 19-alkyne Cholesterol An alkyne derivative of cholesterol for click chemistry

GC63695 Wnt/β-catenin agonist 2

GC63560 ZW4864

GC63559 ZW4864 free base

GC63465 KY-02327

GC63463 Casein Kinase inhibitor A86

GC63446 PF-04802367 PF-04802367 (PF-367) is a highly selective Glycogen synthase kinase-3 (GSK-3) inhibitor with IC50s of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.

GC63336 MRT-81 MRT-81 is a potent antagonist of human and rodent smoothened (Smo) receptors, with an IC50 value of 41 nM in the Shh-light2 cells, exerting potent hedgehog (Hh) signaling pathway inhibiting activity.