Other Signal Transduction(其他信号转导)

Signal Transduction

Cellular responses are triggered by proteins, drugs, or pathogens binding to specific receptors. Receptor mediated signaling is a cascade of enzymatic reactions that amplifies the signal. The agonists and antagonists modulating receptor functionality are essential tools for research and medical practice. read more

Products for Other Signal Transduction

Cat.No. 产品名称 Information
GC25450 GATA4-NKX2-5-IN-1
3i-1000

GATA4-NKX2-5-IN-1 (3i-1000) is a small-molecule compound inhibiting GATA4 and NKX2-5 transcriptional synergy with IC50 of 3 uM
GC52362 ENPP3 Inhibitor 4g An ENPP1 and ENPP3 inhibitor
GC52361 AMARA Peptide (trifluoroacetate salt)
AMARAASAAALARRR-OH, H-Ala-Met-Ala-Arg-Ala-Ala-Ser-Ala-Ala-Ala-Leu-Ala-Arg-Arg-Arg-OH
A peptide substrate for AMPK
GC52336 ENPP1 Inhibitor 43 An ENPP1 inhibitor
GC52328 KYL (trifluoroacetate salt)
KYL Peptide
An EphA4 inhibitor
GC52322 ENPP3 Inhibitor 4t An ENPP3 inhibitor
GC52277 ENPP3 Inhibitor An ENPP3 inhibitor
GC52274 Y-33075 (hydrochloride)
RKI-983, SNJ-1656, Y-39983
An inhibitor of ROCK2
GC52151 PKCθ Inhibitor (hydrochloride)
Protein Kinase C θ Inhibitor
A PKCθ inhibitor
GC52141 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide
2-氯-N-甲基-N-(4-硝基苯基)乙酰胺
A synthetic intermediate
GC52129 3-Amino-5-hydroxybenzoic Acid
3-氨基-5-羟基苯甲酸
A biosynthetic precursor to ansamycin antibiotics
GC52115 S-99 An inhibitor of ASK1
GC52002 Emavusertib
CA-4948
An IRAK4 inhibitor
GC49912 13C20,15N10-Cyclic di-GMP (sodium salt)
13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguanylate, 13C20,15N10-3’,5’-Cyclic diguanylic Acid
An internal standard for the quantification of cyclic di-GMP
GC49890 β-Glycerophosphate-d5 (sodium salt hydrate)
Glycerol 2-Phosphate-d5
An internal standard for the quantification of β-glycerophosphate
GC49789 Dihydronarwedine
二氢加兰他敏盐酸盐
An alkaloid and GSK3β inhibitor
GC49692 Tofacitinib-d3 (citrate)
Tasocitinib-d3 citrate; CP-690550-d3 citrate
An internal standard for the quantification of tofacitinib
GC49556 Cl-Necrostatin-1
7-Cl-Nec-1, 7-Cl-Necrostatin-1, Nec-1f
A RIPK1 inhibitor
GC49494 4-Aminobenzylphosphonic Acid
4-氨基苄基膦酸
An alkaline phosphatase inhibitor
GC49433 Capsiate
辣椒素酯
A capsaicin analog with diverse biological activities
GC49403 Benzarone
苯扎隆,Fragivix
An active metabolite of benzbromarone
GC49392 CHIR98024
CT 98024
A GSK3 inhibitor
GC49334 Chroman 1 (hydrochloride hydrate)
(S)-Chroman 1
A ROCK2 inhibitor
GC49332 Calcineurin Substrate (trifluoroacetate salt)
H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH, H-DLDVPIPGRFDRRVSVAAE-OH
A synthetic peptide substrate
GC49300 BIM-46187 (hydrochloride) An inhibitor of heterotrimeric G-protein signaling
GC49284 GSK-A1 A PI4KIIIα inhibitor
GC49269 Myr-ZIP
Myristoylated-ZIP, Myristoylated Zeta-Pseudosubstrate Inhibitory Peptide, Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu, Myr-SIYRRGARRWRKL-OH, Ζeta Inhibitory Peptide
A PKMζ inhibitor
GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt)
Myr-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2, Myr-GRTGRRNAI-NH2, Myristoylated PKI-(14-22)-amide, PKI-(Myr-14-22)-amide
A PKA inhibitor
GC49221 QLT0267 An ILK inhibitor
GC49150 Tpl2 Kinase Inhibitor (hydrochloride)
c-Cot Kinase Inhibitor, MAP3K8 Kinase Inhibitor, Tumor Progression Locus 2 Kinase Inhibitor
A Tpl2 inhibitor
GC49110 AICA Ribonucleotide
5-氨基咪唑-4-甲酰胺-1-Β-D-呋喃核糖苷5-一磷酸盐
An AMPK activator
GC49090 Nilvadipine-d4
(±)-Nilvadipine-d4
An internal standard for the quantification of nilvadipine
GC49079 C82 An Mtb CdnP inhibitor
GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase
GC48992 CGP 77675 (hydrate) An inhibitor of Src family kinases
GC13855 Eeyarestatin I
An ERAD inhibitor
GC17779 Levetiracetam
左乙拉西坦; UCB L059
An antiepileptic compound
GC11058 Scrambled 10Panx
Scrambled 10Panx Phe-Ser-Val-Tyr-Trp-Ala-Gln-Ala-Asp-Arg

Panx-1 mimetic inhibitory peptide, blocks pannexin-1 gap junctions
GC13863 10Panx
10Panx
A peptide inhibitor of PANX1
GP10004 GTP binding protein 1 fragment [Multiple species]
H2N-Lys-Val-Ile-Thr-Phe-Ile-Asp-Leu-OH
Signal transducing molecules
GP10024 Growth Hormone (1-43), human
H2N-Phe-Pro-Thr-Ile-Pro-Leu-Ser-Arg-Leu-Phe-Asp-Asn-Ala-Met-Leu-Arg-Ala-His-Arg-Leu-His-Gln-Leu-Ala-Phe-Asp-Thr-Tyr-Gln-Glu-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-OH
Human Growth Hormone (1-43) peptide
GP10076 Agouti-related Protein (AGRP) (25-82), human
H2N-Leu-Ala-Pro-Met-Glu-Gly-Ile-Arg-Arg-Pro-Asp-Gln-Ala-Leu-Leu-Pro-Glu-Leu-Pro-Gly-Leu-Gly-Leu-Arg-Ala-Pro-Leu-Lys-Lys-Thr-Thr-Ala-Glu-Gln-Ala-Glu-Glu-Asp-Leu-Leu-Gln-Glu-Ala-Gln-Ala-Leu-Ala-Glu-Val-Leu-Asp-Leu-Gln-Asp-Arg-Glu-Pro-Arg-OH

Agouti-related peptide(25-82)
GP10005 Epidermal growth factor receptor (994-1002) acetyl/amide
Ac-Asp-Ser-Asn-Phe-Tyr-Arg-Ala-Leu-Met-amide

EGF-family receptor
GP10104 S6 Kinase Substrate Peptide 32
H2N-Lys-Glu-Ala-Lys-Glu-Lys-Arg-Gln-Glu-Gln-Ile-Ala-Lys-Arg-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-Ser-Thr-Ser-Lys-Ser-Gly-Gly-Ser-Gln-Lys-OH
Measures the activity of kinases that phosphorylate ribosomal protein S6.
GP10011 Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell
Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys-OH
一氧化氮生产阻滞剂
GP10062 Endothelin-1 (1-15), amide, human
H2N-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-NH2

Vasoconstrictor agent
GP10117 Endostatin (84-114)-NH2 (JKC367)
H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2
血管生成抑制剂
GP10071 BNP (1-32), human
醋酸奈西立肽,H2N-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH
脑利钠肽
GP10145 signal transducer and activator of transcription 6 fragment
H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH

STAT6 transcription factor
GP10042 Rhodopsin peptide
H2N-Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala-OH
视网膜感光细胞色素;GPCR