Tyrosine Kinase(酪氨酸激酶)
- Bcr-Abl(60)
- Ack1(2)
- Axl(6)
- ALK(53)
- BMX Kinase(3)
- Broad Spectrum Protein Kinase Inhibitor(10)
- c-FMS(30)
- c-Kit(53)
- c-MET(70)
- c-RET(7)
- CSF-1R(3)
- DDR1/DDR2 Receptor(1)
- EGFR(201)
- EphB4(1)
- FAK(32)
- FGFR(83)
- FLT3(82)
- HER2(15)
- IGF1R(25)
- Insulin Receptor(35)
- IRAK(23)
- ITK(9)
- Lck(1)
- LRRK2(20)
- PDGFR(94)
- PTKs/RTKs(3)
- Pyk2(6)
- ROR(35)
- Spleen Tyrosine Kinase (Syk)(31)
- Src(88)
- Tie-2 (3)
- Trk(33)
- VEGFR(168)
- Discoidin Domain Receptor(14)
- DYRK(23)
- Ephrin Receptor(9)
- RET(25)
- ROS(14)
- TAM Receptor(27)
- IGFBR(1)
- Others(55)
- Cat.No. 产品名称 Information
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GP26200
TYRO3 Mouse
TYRO3 Mouse produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 628 amino acids (31-419 aa) and having a molecular mass of 68
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GP26187
ErbB4 Human
ErbB4 Human Recombinant produced in HEK293 Cells is a single, glycosylated polypeptide chain containing 863 amino acids (26-649 a
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GC26063
WAY-340935
WAY-340935 (VEGFR2-IN-2) can inhibit the function of VEGFR2 and the anti-proliferative activity against the H460 cell line is produced partly by interaction of VEGFR protein.
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GC26021
UNC2025 HCl
UNC2025 HCl is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.
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GC26001
TPX-0046
TPX-0046 is a novel RET/SRC inhibitor with a mean IC50 of 17 nM for RETG810R in Ba/F3 cell proliferation assay
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GC25969
SU5208
SU5208(3-[(Thien-2-yl)methylene]-2-indolinone) is an inhibitor of vascular endothelial growth factor receptor-2 (VEGFR2).
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GC25881
S961
S961 is a biosynthetic insulin receptor antagonist that inhibits cellular proliferation and colony formation in breast tumour cells.
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GC25787
PRT-060318 2HCl
PRT-060318 (PRT318) is a novel selective inhibitor of the Syk tyrosine kinase with an IC50 of 4 nM, as an approach to HIT treatment.
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GC25669
Nilotinib hydrochloride
Nilotinib hydrochloride (AMN-107) is the hydrochloride salt form of nilotinib, an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.
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GC25559
Lapatinib (GW-572016) Ditosylate
Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively.
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GC25367
Ehp-inhibitor-1
Ehp-inhibitor-1 (Ehp inhibitor 2) is an Eph family tyrosine kinase inhibitor that targets Eph receptors.
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GC25313
CS-2660 (JNJ-38158471)
CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as RET (c-RET) and Kit (c-Kit) with IC50 of 180 nM and 500 nM,while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3.
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GC25219
CH7233163
CH7233163 is a non-covalent ATP competitive inhibitor of EGFR-tyrosine kinase with antitumor activities against tumor with EGFR-Del19/T790M/C797S.
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GC25092
Apatinib (YN968D1) mesylate
Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.
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GC25073
Anlotinib (AL3818) dihydrochloride
Anlotinib (AL3818) is a highly potent and selective VEGFR2 inhibitor with IC50 less than 1 nM. It has broad-spectrum antitumor potential in clinical trials. Please use saline solution rather than PBS for dilutions. PBS may cause precipitation.
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GC25017
4,4'-Bis(4-aminophenoxy)biphenyl
4,4'-Bis(4-aminophenoxy)biphenyl is a monomer for polyimide production.
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GC25000
(E/Z)-BCI
(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.
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GC68463
ULK1-IN-2
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GC68458
HS-243
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GC68447
GSK143 dihydrochloride
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GC68440
EGFR-IN-69
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GC68433
OTS447
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GC68430
Selatinib
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GC68411
RORγt Inverse agonist 10
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GC68396
Vepafestinib
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GC68342
Tilvestamab
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GC68321
O-Desmethyl gefitinib-d8
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GC68304
Margetuximab
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GC68030
FAK-IN-7
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GC68018
MET kinase-IN-2
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GC67998
Insulin degludec
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GC67948
Cabozantinib-d6
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GC67917
RET-IN-7
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GC67879
Edecesertib
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GC67878
TL4830031
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GC67860
JBJ-09-063 TFA
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GC67774
CT52923
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GC67759
Lapatinib-d4
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GC67749
Amivantamab
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GC67690
JBJ-09-063 hydrochloride
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GC52516
Erbstatin
A tyrosine kinase inhibitor
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GC52472
Inostamycin A (sodium salt)
A bacterial metabolite with anticancer activity
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GC66476
DDR1-IN-6
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GC66451
AKN-028 acetate
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GC66432
EAI001
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GC66428
EGFR-IN-5
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GC66405
Panitumumab
Panitumumab (anti-EGFR, ABX-EGF) is a recombinant, fully human IgG2 monoclonal antibody that binds to the epidermal growth factor receptor (EGFR).
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GC66385
Tovetumab
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GC66349
Mavrilimumab
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GC66333
Panitumumab (anti-EGFR)