Home >> Signaling Pathways >> Tyrosine Kinase >> VEGFR

VEGFR(血管内皮生长因子受体)

VEGFR are receptors for vascular endothelial growth factor and belong to receptor tyrosine kinases.

  1. Cat.No. 产品名称 Information
  2. GC26063 WAY-340935 WAY-340935 (VEGFR2-IN-2) can inhibit the function of VEGFR2 and the anti-proliferative activity against the H460 cell line is produced partly by interaction of VEGFR protein.
  3. GC25969 SU5208 SU5208(3-[(Thien-2-yl)methylene]-2-indolinone) is an inhibitor of vascular endothelial growth factor receptor-2 (VEGFR2).
  4. GC25092 Apatinib (YN968D1) mesylate Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.
  5. GC25073 Anlotinib (AL3818) dihydrochloride Anlotinib (AL3818) is a highly potent and selective VEGFR2 inhibitor with IC50 less than 1 nM. It has broad-spectrum antitumor potential in clinical trials. Please use saline solution rather than PBS for dilutions. PBS may cause precipitation.
  6. GC25017 4,4'-Bis(4-aminophenoxy)biphenyl 4,4'-Bis(4-aminophenoxy)biphenyl is a monomer for polyimide production.
  7. GC67948 Cabozantinib-d6
  8. GC66043 VEGFR-2-IN-29
  9. GC65335 PTC299 A DHODH inhibitor
  10. GC64996 Tivozanib hydrochloride hydrate
  11. GC64950 ODM-203 A dual inhibitor of VEGFR and FGFR
  12. GC64895 Regorafenib-d3
  13. GC64836 Famitinib
  14. GC64346 Pegaptanib sodium
  15. GC64205 VEGFR-3-IN-1
  16. GC63805 4SC-203 4SC-203 (SC71710) is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).
  17. GC49700 Takeda-6d A dual inhibitor of RAF kinases and VEGFR2
  18. GC49686 N-desmethyl Regorafenib N-oxide An active metabolite of regorafenib
  19. GC63214 Telatinib mesylate A multi-kinase inhibitor
  20. GC62291 (Z)-Orantinib
  21. GC62185 Axitinib-d3
  22. GC62145 Chiauranib Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR)/platelet-derived growth factor receptor (PDGFR)/c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy.
  23. GC61780 SU5204 SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively.
  24. GC61600 VEGFR-2-IN-6
  25. GC61454 GW806742X hydrochloride
  26. GC48118 Sunitinib-d10 An internal standard for the quantification of sunitinib
  27. GC60726 CP-547632 TFA A potent inhibitor of VEGFR2 and bFGF
  28. GC60365 TIE-2/VEGFR-2 kinase-IN-1
  29. GC60283 Pentagamavunon-1
  30. GC50330 BMS 605541 Potent VEGFR-2 inhibitor
  31. GC50233 Vatalanib succinate Potent VEGFR inhibitor; also aromatase inhibitor
  32. GC50028 ZM 306416 hydrochloride A VEGF receptor kinase inhibitor
  33. GC39314 Tyrphostin AG1433 Tyrphostin AG1433 (AG1433, SU1433) is a selective platelet-derived growth factor receptor β (PDGFRβ) and vascular endothelial growth factor receptor 2 (VEGFR-2, Flk-1/KDR) inhibitor with IC50s of 5.0 μM and 9.3 μM, respectively.
  34. GC45828 Ponatinib-d8 An internal standard for the quantification of ponatinib
  35. GC38575 CP-547632 hydrochloride A potent inhibitor of VEGFR2 and bFGF
  36. GC38519 Ilorasertib hydrochloride A multi-kinase inhibitor
  37. GC38380 Vorolanib X-82 (Vorolanib, CM082) is an oral, multikinase, dual inhibitor of vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR) with antiangiogenic and antineoplastic activities.
  38. GC37933 WHI-P180 hydrochloride A multi-kinase inhibitor
  39. GC37886 Vandetanib trifluoroacetate A multi-kinase inhibitor
  40. GC37808 Toceranib phosphate A multi-targeted receptor tyrosine kinase inhibitor
  41. GC37773 TG 100801 Hydrochloride
  42. GC37772 TG 100572 Hydrochloride
  43. GC37771 TG 100572
  44. GC37665 Sorafenib (D4)
  45. GC37664 Sorafenib (D3) An internal standard for the quantification of sorafenib
  46. GC37538 Ripretinib A KIT and PDGFRα inhibitor
  47. GC37047 Pz-1
  48. GC36745 Nintedanib esylate

    Nintedanib esylate, as a kinase inhibitor, used for the treatment of non-small cell lung cancer suffered from first-pass metabolism which resulted in low oral bioavailability .

  49. GC36744 Ningetinib Tosylate A multi-kinase inhibitor
  50. GC36438 Lenvatinib mesylate An inhibitor of VEGFR2 and VEGFR3
  51. GC36203 GW806742X

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