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Home >> Signaling Pathways >> Tyrosine Kinase >> VEGFR

VEGFR(血管内皮生长因子受体)

VEGFR are receptors for vascular endothelial growth factor and belong to receptor tyrosine kinases.

Products for  VEGFR

  1. Cat.No. 产品名称 Information
  2. GC17800 (E)-FeCP-oxindole VEGFR-2 inhibitor
  3. GC13944 (5Z)-7-Oxozeaenol A selective TAK1 inhibitor
  4. GC11417 SU 4312 A selective dual inhibitor of VEGFR2 and PDGFR
  5. GC16183 EG00229 An NRP-1 antagonist
  6. GC13833 BMS-794833 An inhibitor of c-Met and VEGFR2
  7. GC10758 Tyrphostin 9 An inhibitor of EGF receptor kinase
  8. GC11555 ZM 323881 HCl A potent and selective VEGFR2 inhibitor
  9. GC12586 SAR131675 An inhibitor of VEGFR3
  10. GC14292 Apatinib Mesylate

    A selective VEGFR2 inhibitor
  11. GC17715 Golvatinib (E7050) A dual inhibitor of c-Met and VEGFR2
  12. GC12980 CP-673451 A selective PDGFRα/β kinase inhibitor
  13. GC12531 Cabozantinib malate (XL184) A VEGFR2 inhibitor
  14. GC11003 PP121 A potent dual inhibitor of tyrosine and phosphoinositide kinases
  15. GC17651 Sunitinib Sunitinib (SU 11248) 是一种多靶点受体酪氨酸激酶抑制剂，对 VEGFR2 和 PDGFRβ 的 IC50 分别为 80 nM 和 2 nM。 Sunitinib 是一种 ATP 竞争性抑制剂，通过抑制自身磷酸化和随后的 RNase 激活，有效抑制 Ire1α 的自身磷酸化。
  16. GC10220 TAK-593 TAK-593 是一种有效的 VEGFR 和 PDGFR 家族抑制剂，对 VEGFR1、VEGFR2、VEGFR3、PDFGRα 和 PDFGRβ 的 IC50 分别为 3.2、0.95、1.1、4.3 和 13 nM。
  17. GC13738 SKLB1002 A VEGFR2 inhibitor
  18. GC12185 ZM 306416 A VEGF receptor kinase inhibitor
  19. GC16000 WHI-P180 A multi-kinase inhibitor
  20. GC15022 Vandetanib (ZD6474) A multi-kinase inhibitor
  21. GC11763 Telatinib (BAY 57-9352) A multi-kinase inhibitor
  22. GC11372 Dovitinib Dilactic acid FLT3 inhibitor
  23. GC12216 Axitinib (AG 013736) A VEGFR inhibitor
  24. GC12730 Pazopanib Hydrochloride A multi-kinase inhibitor
  25. GC15818 RAF265 A B-Raf and VEGFR2 inhibitor
  26. GC12590 KRN 633 A VEGF receptor tyrosine kinase inhibitor
  27. GC14396 Ponatinib (AP24534) An inhibitor of native and mutant Bcr-Abl
  28. GC16732 TSU-68 (SU6668,Orantinib) An inhibitor of select receptor tyrosine kinases
  29. GC17955 Vatalanib (PTK787) 2HCl A potent and selective VEGF receptor inhibitor
  30. GC14238 Brivanib Alaninate (BMS-582664) A prodrug form of brivanib
  31. GC15735 Foretinib (GSK1363089) A broad-spectrum tyrosine kinase inhibitor
  32. GC11336 Motesanib Diphosphate (AMG-706) A multikinase inhibitor
  33. GC13598 MGCD-265 A c-Met and VEGFR2 inhibitor
  34. GC15454 Lenvatinib (E7080)

    An inhibitor of VEGFR2 and VEGFR3
  35. GC14957 OSI-930 A dual inhibitor of Kit and VEGFR2
  36. GC11692 Brivanib (BMS-540215) A VEGFR1, VEGFR2, and FGFR1 inhibitor
  37. GC12036 Tivozanib (AV-951) Tivozanib (AV-951; KRN951) 是一种有效的、选择性的、具有口服活性的 VEGFR 酪氨酸激酶抑制剂，对 VEGFR-1、VEGFR-2、VEGFR-3 的 IC50 分别为 0.21、0.16、0.24 nM。 Tivozanib 抑制肿瘤组织中的血管生成和血管通透性，并显示出抗肿瘤活性。 Tivozanib 具有研究转移性肾细胞癌（RCC）的潜力。
  38. GC15779 Cabozantinib (XL184, BMS-907351) A VEGFR2 inhibitor
  39. GC16421 Cediranib (AZD217) An inhibitor of VEGF receptor tyrosine kinases
  40. GC13547 Dovitinib (TKI-258, CHIR-258) A multi-kinase inhibitor
  41. GC17958 Linifanib (ABT-869) A dual VEGFR and PDGFR family kinase inhibitor
  42. GC11666 Ki8751 A potent, orally available VEGFR2 inhibitor
  43. GC14683 Sunitinib malate A multi-kinase inhibitor
  44. GC17943 PD 173074 Inhibitor of tyrosine kinase activity of fibroblast growth factor receptors
  45. GC11705 Nintedanib (BIBF 1120) A VEGFR, FGFR, and PDGFR inhibitor
  46. GC16499 Sorafenib Tosylate A multi-kinase inhibitor
  47. GC12776 SKLB610 An inhibitor of VEGFR2
  48. GC10111 Regorafenib A multi-kinase inhibitor
  49. GC14464 Vatalanib A potent and selective VEGF receptor inhibitor
  50. GC12656 ZM323881 A potent and selective VEGFR2 inhibitor
  51. GC11876 Vandetanib hydrochloride A multi-kinase inhibitor

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