Home >> Signaling Pathways >> Ubiquitination/ Proteasome

Ubiquitination/ Proteasome(泛素化/蛋白酶体)

  1. Cat.No. 产品名称 Information
  2. GC20117 CB-5339

    CB-5339 is a second generation, potent and selective, orally bioavailable, ATP-competitive, small molecule inhibitor of valosin containing protein (VCP)/p97 [1,2].

  3. GC25651 MRT68921 HCl MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
  4. GC25650 MRT67307 HCl MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy.
  5. GC25019 5-amino-2,4-dimethylpyridine (5A-DMP) 5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts
  6. GC67908 Calpain-2-IN-1
  7. GC52477 Corynoxine (hydrochloride) An indole alkaloid
  8. GC52467 Cell Death Screening Library For screening a variety of cell death pathways
  9. GC52447 Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt) A fluorogenic substrate for the 20S proteasome and calpains
  10. GC52272 Jun9-72-2 A SARS-CoV-2 PLpro inhibitor
  11. GC65938 Thrombin inhibitor 5 WAY-358871 is a bioactive compound.
  12. GC65668 5-Amino-8-hydroxyquinoline
  13. GC65575 Cabazitaxel-d6
  14. GC65547 (1S,2R)-Alicapistat
  15. GC65540 eIF4A3-IN-2
  16. GC65432 LV-320
  17. GC65386 Trimetazidine-d8 dihydrochloride
  18. GC65331 IZCZ-3
  19. GC65318 BOLD-100
  20. GC65307 S130
  21. GC65297 MW-150 An inhibitor of p38α MAPK
  22. GC65191 DC-LC3in-D5
  23. GC65115 mTOR inhibitor-1 mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy.
  24. GC65106 Pregnenolone-d4-1
  25. GC65072 Niacin-13C6
  26. GC65010 Bortezomib-d8
  27. GC65004 Apostatin-1 Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). Apostatin-1 inhibits bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.
  28. GC64694 UPCDC-30245
  29. GC64607 Dazcapistat
  30. GC64524 Clematichinenoside AR
  31. GC64472 20S Proteasome-IN-1
  32. GC52057 QN523 An anticancer agent
  33. GC49815 Oleuropein aglycone A polyphenol with diverse biological activities
  34. GC64378 Valproic acid-d6
  35. GC64363 Lumefantrine-d9
  36. GC64358 Olacaftor
  37. GC64325 Ligustilide Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. Solutions are best fresh-prepared.
  38. GC64282 LXE408
  39. GC64223 Sophocarpine monohydrate An alkaloid with diverse biological activities
  40. GC64213 GSK3494245
  41. GC64136 Desmethyl Naproxen-d3
  42. GC64113 Lamotrigine-13C3,d3
  43. GC64098 Isoniazid-d4
  44. GC64076 Nortriptyline Nortriptyline hydrochloride (Desitriptyline, ELF-101, EN-7048, Desmethylamitriptyline) is the hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression.
  45. GC64070 Omeprazole-d3-1 An internal standard for the quantification of omeprazole
  46. GC64032 Salicylic acid-d6
  47. GC64013 ZX-29 ZX-29 is a potent and selective ALK inhibitor with an IC50s of 2.1, 1.3 and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively.
  48. GC64003 Carvedilol-d4
  49. GC63964 PR-39 TFA
  50. GC63840 Tat-beclin 1 Tat-beclin 1 (Tat-BECN1), a peptide known to stimulate autophagy through mobilization of endogenous Beclin 1, induces autophagy in vitro and in vivo and improves clinical outcomes.
  51. GC63827 Atropine sulfate monohydrate A non-selective muscarinic acetylcholine receptor antagonist

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