Ubiquitination/ Proteasome(泛素化/蛋白酶体)

Cat.No. 产品名称 Information

GC20117 CB-5339

CB-5339 is a second generation, potent and selective, orally bioavailable, ATP-competitive, small molecule inhibitor of valosin containing protein (VCP)/p97 [1,2].

GC25651 MRT68921 HCl MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.

GC25650 MRT67307 HCl MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy.

GC25019 5-amino-2,4-dimethylpyridine (5A-DMP) 5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts

GC67908 Calpain-2-IN-1

GC52477 Corynoxine (hydrochloride) An indole alkaloid

GC52467 Cell Death Screening Library For screening a variety of cell death pathways

GC52447 Suc-Leu-Leu-Val-Tyr-AMC (trifluoroacetate salt) A fluorogenic substrate for the 20S proteasome and calpains

GC52272 Jun9-72-2 A SARS-CoV-2 PL^pro inhibitor

GC65938 Thrombin inhibitor 5 WAY-358871 is a bioactive compound.

GC65668 5-Amino-8-hydroxyquinoline

GC65575 Cabazitaxel-d6

GC65547 (1S,2R)-Alicapistat

GC65540 eIF4A3-IN-2

GC65432 LV-320

GC65386 Trimetazidine-d8 dihydrochloride

GC65331 IZCZ-3

GC65318 BOLD-100

GC65307 S130

GC65297 MW-150 An inhibitor of p38α MAPK

GC65191 DC-LC3in-D5

GC65115 mTOR inhibitor-1 mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy.

GC65106 Pregnenolone-d4-1

GC65072 Niacin-13C6

GC65010 Bortezomib-d8

GC65004 Apostatin-1 Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). Apostatin-1 inhibits bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.

GC64694 UPCDC-30245

GC64607 Dazcapistat

GC64524 Clematichinenoside AR

GC64472 20S Proteasome-IN-1

GC52057 QN523 An anticancer agent

GC49815 Oleuropein aglycone A polyphenol with diverse biological activities

GC64378 Valproic acid-d6

GC64363 Lumefantrine-d9

GC64358 Olacaftor

GC64325 Ligustilide Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. Solutions are best fresh-prepared.

GC64282 LXE408

GC64223 Sophocarpine monohydrate An alkaloid with diverse biological activities

GC64213 GSK3494245

GC64136 Desmethyl Naproxen-d3

GC64113 Lamotrigine-13C3,d3

GC64098 Isoniazid-d4

GC64076 Nortriptyline Nortriptyline hydrochloride (Desitriptyline, ELF-101, EN-7048, Desmethylamitriptyline) is the hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression.

GC64070 Omeprazole-d3-1 An internal standard for the quantification of omeprazole

GC64032 Salicylic acid-d6

GC64013 ZX-29 ZX-29 is a potent and selective ALK inhibitor with an IC50s of 2.1, 1.3 and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively.

GC64003 Carvedilol-d4

GC63964 PR-39 TFA

GC63840 Tat-beclin 1 Tat-beclin 1 (Tat-BECN1), a peptide known to stimulate autophagy through mobilization of endogenous Beclin 1, induces autophagy in vitro and in vivo and improves clinical outcomes.

GC63827 Atropine sulfate monohydrate A non-selective muscarinic acetylcholine receptor antagonist