Home >> Signaling Pathways >> Ubiquitination/ Proteasome >> p97


p97 is a AAA-type ATPase that involved in mitosis-related events, such as golgi stacks fragmentation, tER formation, spindle pole body function and homotypic membrane fusion etc.

Products for  p97

  1. Cat.No. 产品名称 Information
  2. GC20117 CB-5339

    CB-5339 is a second generation, potent and selective, orally bioavailable, ATP-competitive, small molecule inhibitor of valosin containing protein (VCP)/p97 [1,2].

  3. GC64694 UPCDC-30245 UPCDC-30245 是一种变构 p97 (allosteric p97) 抑制剂,IC50 约为 27 nM。UPCDC-30245 抑制 p97 突变体 N660K 的效力与野生型 (IC50=300 nM) 相似,此外对 p97 突变体 T688A 仅表现出 3 倍的耐药性。UPCDC-30245可用于癌症研究。
  4. GC60257 MSC1094308 MSC1094308 是一种可逆的、II 型 AAA ATPase (VCP)/p97 和I型 AAA ATPase VPS4B 的变构抑制剂,对VPS4B 和 p97 的IC50 值分别为 0.71 μM 和 7.2 μM。
  5. GC32874 NMS-859 NMS-859是一种有效的,共价的VCP(p97)抑制剂,细胞中分别在60μM和1mMATP的条件下,对野生型VCP的IC50值分别为0.37和0.36μM。
  6. GC13656 ML241 hydrochloride ML241 hydrochloride 是一种有效的 p97 抑制剂,抑制 p97 ATPase,IC50 值为 100 nM。
  7. GC11749 ML241 p97 ATPase inhibitor
  8. GC16351 CB-5083 An orally bioavailable inhibitor of p97
  9. GC14059 ML 240 A selective inhibitor of the ATPase p97
  10. GC17250 NMS-873 A selective inhibitor of VCP/p97
  11. GC10048 MNS An inhibitor of Src, Syk, and platelet aggregation
  12. GC10824 DBeQ A selective inhibitor of the ATPase p97

11 Item(s)

per page

Set Descending Direction