Home >> Signaling Pathways >> Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

  1. Cat.No. 产品名称 Information
  2. GC26033 Veratrine Veratridine (Cevadine, Cevadin, Cevadene), a steroidal alkaloid found in plants of the lily family, is a voltage-gated sodium channel activator. Veratridine induces anxiogenic-like behaviors in rats.
  3. GC26029 Valbenazine tosylate Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).
  4. GC25991 tetrathiomolybdate Tetrathiomolybdate (TM) is used in the clinic for the treatment of Wilson's disease by inducing dimerization of the metal-binding domain of the cellular copper efflux protein ATP7B (WLN4) through a unique sulfur-bridged Mo2S6O2 cluster.
  5. GC25936 SLC13A5-IN-1 SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5/NaCT). It completely blocks the uptake of 14 C-citrate and has the potential for the treatment of metabolic and/or cardiovascular diseases.
  6. GC25812 Quinidine sulfate Quinidine (Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.
  7. GC25566 L-DAB HBR L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) is an inhibitor of GABA (Gamma-aminobutyric acid) transaminase with IC50 of >500 μM
  8. GC25558 Lanthanum(III) chloride heptahydrate Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.
  9. GC25531 Isonipecotic acid Isonipecotic acid (4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid) is a heterocyclic compound that mainly acts as a GABAA receptor partial agonist.
  10. GC25405 Evodine Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor.
  11. GC25386 Ethacrynate Sodium Ethacrynate Sodium (ethacrynic acid sodium) is the sodium salt form of ethacrynic acid, which inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.
  12. GC25345 Deudextromethorphan (AVP-786) Deudextromethorphan (AVP-786) is an active N-methyl-D-aspartate (NMDA) receptor antagonist.
  13. GC25174 Brucine sulfate heptahydrate Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons.
  14. GC25134 Benzocaine hydrochloride Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
  15. GC67996 TPA-023B
  16. GC67949 GNE-0439
  17. GC67939 CFTR corrector 4
  18. GC67925 Crinecerfont hydrochloride
  19. GC67924 Dihydrocapsiate
  20. GC67922 Zelquistinel
  21. GC67920 WS-898
  22. GC67895 EVT-401
  23. GC67871 SSR504734
  24. GC67799 PF-05198007
  25. GC67789 SRI-37240
  26. GC67784 ML-SI3
  27. GC67767 (R)-Olacaftor
  28. GC67747 Dalazatide TFA
  29. GC67739 D-erythro-Sphingosine hydrochloride
  30. GC52503 FTase Inhibitor II (trifluoroacetate salt) A potent, selective inhibitor of farnesyltransferase
  31. GC52466 ICR-1 (potassium salt) A cell-impermeable fluorescent calcium indicator
  32. GC52465 ICR-1 AM A cell-permeable fluorescent calcium indicator
  33. GC52250 Mevalonate (lithium salt) An intermediate in the mevalonate pathway
  34. GC66843 L-Homocysteic acid
  35. GC66836 Dimethyl L-glutamate
  36. GC66470 SW157765
  37. GC66436 FEMA 4809
  38. GC66419 (R)-Lercanidipine-d3 hydrochloride
  39. GC66255 (E)-3,4,5-Trimethoxycinnamic acid
  40. GC66240 Lei-Dab7 TFA
  41. GC66073 Flupyradifurone
  42. GC66038 PF-06649298
  43. GC66016 Evifacotrep
  44. GC65999 piCRAC-1
  45. GC65959 CaV1.3 antagonist-1
  46. GC65954 Plazinemdor
  47. GC65940 Zandatrigine
  48. GC65611 AMG 333 A TRPM8 antagonist
  49. GC65593 6-Benzoylheteratisine
  50. GC65536 TRPV4 agonist-1
  51. GC65531 Hardwickiic acid

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