NMDA Receptor(NMDA受体)
NMDA (N-methyl-D-aspartate) receptor is a glutamate-gated cation channels that plays a vital role in regulating synaptic transmission, neuroplasticity and central nervous system development. It is involved in a range of physiological processes such as learning, memory and pain etc.
- Cat.No. 产品名称 Information
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GC11124
Lanicemine
A low-trapping NMDA channel blocker
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GC11025
(+)-MK 801 Maleate
An NMDA receptor antagonist
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GC16315
D-AP5
A selective NMDA antagonist
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GC11862
LY 233053
Competitive NMDA receptor antagonist
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GC16776
QNZ 46
An antagonist of NR2C- and NR2D-subunit containing NMDA receptors
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GC10085
DQP 1105
An NMDA receptor antagonist
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GC14770
TCN 213
TCN 213 是一种选择性的、可克服的、依赖甘氨酸的 GluN1/GluN2A NMDAR 拮抗剂,在 75、750、7500 nM 甘氨酸存在下,IC50 分别为 0.55、3.5、40 μM。
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GC15065
TCN 201
An NR2A-selective NMDA receptor antagonist
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GC10247
PPDA
PPDA 是一种亚型选择性 NMDA 受体拮抗剂,它优先与含有 NR2C/NR2D 的受体结合。
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GC10688
MNI-caged-D-aspartate
Agonist at NMDA receptors and EAAT substrate
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GC10574
Norketamine hydrochloride
Major metabolite of ketamine, NMDA receptor antagonist
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GC14414
CIQ
A subunit-selective NMDA receptor potentiator
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GC14598
5,7-Dichlorokynurenic acid sodium salt
An NMDA receptor antagonist
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GC14897
DL-AP5 Sodium salt
A competitive NMDA antagonist
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GC14381
Ro 8-4304 hydrochloride
NMDA receptor antagonist
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GC10595
threo Ifenprodil hemitartrate
σ receptor agonist and NR2B subunit-selective NMDA receptor antagonist
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GC14442
TCS 46b
NR1A/NR2B NMDA receptor antagonist,orally active
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GC10792
Co 101244 hydrochloride
Co 101244 (PD 174494) hydrochloride 是一种含有 NR2B 的 NMDA 受体拮抗剂。
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GC17481
Gavestinel
An NMDA receptor antagonist
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GC11879
PPPA
PPPA 是一种竞争性 NMDA 受体拮抗剂,对含 NR2A 的受体具有中等选择性。
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GC14357
PMPA (NMDA antagonist)
PMPA(NMDA 拮抗剂)是一种 NMDA 受体拮抗剂,对 NR2A、NR2B、NR2C 和 NR2D 的 Ki 值分别为 0.84、2.74、3.53 和 4.16 μM。
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GC11281
N20C hydrochloride
NMDA receptor antagonist
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GC15343
Eliprodil
An NMDA receptor antagonist
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GC14782
Ro 04-5595 hydrochloride
NR2B-containing NMDA receptors antagonist
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GC16131
Remacemide hydrochloride
Remacemide hydrochloride (FPL 12924AA) 是 Na+ 通道的中度抑制剂,是一种弱的非竞争性 NMDA 受体拮抗剂,对 MK-801 结合和 NMDA 电流的 IC50 分别为 68 μM 和 76 μM。
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GC15752
CGP 78608 hydrochloride
CGP 78608 hydrochloride 是一种高效的选择性拮抗剂,作用于 NMDA 受体的甘氨酸结合位点,IC50 为 6 nM。
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GC10122
CGP 37849
CGP 37849 是一种有效的、竞争性的和具有口服活性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。
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GC11027
CGP 39551
CGP 39551 是一种有效的、具有口服活性的竞争性 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂,具有有效的抗惊厥活性。
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GC12816
SDZ 220-040
NMDA receptor antagonist
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GC16272
CGS 19755
NMDA receptor antagonist
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GC12137
CCMQ
inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sites
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GC12873
LY 235959
NMDA receptor antagonist
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GC14810
L-701,324
An NMDA receptor antagonist
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GC10696
L-689,560
L-689,560 是一种有效的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂,作用于 GluN1 甘氨酸结合位点。
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GC11706
L-701,252
L-701,252 是一种有效的甘氨酸位点 NMDA 受体拮抗剂,IC50 为 420 nM。
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GC15732
Synthalin sulfate
NMDA receptor antagonist
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GC10471
Ifenprodil hemitartrate
An NMDA receptor antagonist
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GC10237
(±)-1-(1,2-Diphenylethyl)piperidine maleate
NMDA receptor antagonist
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GC10168
(R)-4-Carboxyphenylglycine
NMDA receptor antagonist
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GC12488
(RS)-(Tetrazol-5-yl)glycine
An NMDA receptor agonist
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GC16799
5,7-Dichlorokynurenic acid
An NMDA receptor antagonist
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GC10370
(S)-(-)-HA-966
(S)-(-)-HA-966 ((-)-HA 966) 是一种 γ-Hydroxybutyrate 样剂,作为 NMDA 受体拮抗剂的活性较弱。
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GC14085
(R)-(+)-HA-966
(R)-(+)-HA-966 ((+)-HA-966) 是 N-甲基-D-天冬氨酸 (NMDA) 受体复合物甘氨酸位点的部分激动剂/拮抗剂。
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GC14236
(R)-CPP
An NMDA receptor antagonist
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GC10114
Homoquinolinic acid
NMDA receptor agonist
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GC11942
cis-ACPD
cis-ACPD 是一种有效的 NMDA 受体激动剂,IC50 为 3.3 μM。
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GC10476
(RS)-CPP
NMDA antagonist
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GC15112
D-AP7
NMDA receptor antagonist
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GC12154
L-AP5
NMDA拮抗剂
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GC17206
DL-AP5
A competitive NMDA antagonist