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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> NMDA Receptor

NMDA Receptor(NMDA受体)

NMDA (N-methyl-D-aspartate) receptor is a glutamate-gated cation channels that plays a vital role in regulating synaptic transmission, neuroplasticity and central nervous system development. It is involved in a range of physiological processes such as learning, memory and pain etc.

  1. Cat.No. 产品名称 Information
  2. GC11124 Lanicemine A low-trapping NMDA channel blocker
  3. GC11025 (+)-MK 801 Maleate

    An NMDA receptor antagonist
  4. GC16315 D-AP5 A selective NMDA antagonist
  5. GC11862 LY 233053 Competitive NMDA receptor antagonist
  6. GC16776 QNZ 46 An antagonist of NR2C- and NR2D-subunit containing NMDA receptors
  7. GC10085 DQP 1105 An NMDA receptor antagonist
  8. GC14770 TCN 213 TCN 213 是一种选择性的、可克服的、依赖甘氨酸的 GluN1/GluN2A NMDAR 拮抗剂，在 75、750、7500 nM 甘氨酸存在下，IC50 分别为 0.55、3.5、40 μM。
  9. GC15065 TCN 201 An NR2A-selective NMDA receptor antagonist
  10. GC10247 PPDA PPDA 是一种亚型选择性 NMDA 受体拮抗剂，它优先与含有 NR2C/NR2D 的受体结合。
  11. GC10688 MNI-caged-D-aspartate Agonist at NMDA receptors and EAAT substrate
  12. GC10574 Norketamine hydrochloride Major metabolite of ketamine, NMDA receptor antagonist
  13. GC14414 CIQ A subunit-selective NMDA receptor potentiator
  14. GC14598 5,7-Dichlorokynurenic acid sodium salt An NMDA receptor antagonist
  15. GC14897 DL-AP5 Sodium salt A competitive NMDA antagonist
  16. GC14381 Ro 8-4304 hydrochloride NMDA receptor antagonist
  17. GC10595 threo Ifenprodil hemitartrate σ receptor agonist and NR2B subunit-selective NMDA receptor antagonist
  18. GC14442 TCS 46b NR1A/NR2B NMDA receptor antagonist,orally active
  19. GC10792 Co 101244 hydrochloride Co 101244 (PD 174494) hydrochloride 是一种含有 NR2B 的 NMDA 受体拮抗剂。
  20. GC17481 Gavestinel An NMDA receptor antagonist
  21. GC11879 PPPA PPPA 是一种竞争性 NMDA 受体拮抗剂，对含 NR2A 的受体具有中等选择性。
  22. GC14357 PMPA (NMDA antagonist) PMPA（NMDA 拮抗剂）是一种 NMDA 受体拮抗剂，对 NR2A、NR2B、NR2C 和 NR2D 的 Ki 值分别为 0.84、2.74、3.53 和 4.16 μM。
  23. GC11281 N20C hydrochloride NMDA receptor antagonist
  24. GC15343 Eliprodil An NMDA receptor antagonist
  25. GC14782 Ro 04-5595 hydrochloride NR2B-containing NMDA receptors antagonist
  26. GC16131 Remacemide hydrochloride Remacemide hydrochloride (FPL 12924AA) 是 Na+ 通道的中度抑制剂，是一种弱的非竞争性 NMDA 受体拮抗剂，对 MK-801 结合和 NMDA 电流的 IC50 分别为 68 μM 和 76 μM。
  27. GC15752 CGP 78608 hydrochloride CGP 78608 hydrochloride 是一种高效的选择性拮抗剂，作用于 NMDA 受体的甘氨酸结合位点，IC50 为 6 nM。
  28. GC10122 CGP 37849 CGP 37849 是一种有效的、竞争性的和具有口服活性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。
  29. GC11027 CGP 39551 CGP 39551 是一种有效的、具有口服活性的竞争性 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂，具有有效的抗惊厥活性。
  30. GC12816 SDZ 220-040

    NMDA receptor antagonist
  31. GC16272 CGS 19755 NMDA receptor antagonist
  32. GC12137 CCMQ inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sites
  33. GC12873 LY 235959 NMDA receptor antagonist
  34. GC14810 L-701,324 An NMDA receptor antagonist
  35. GC10696 L-689,560 L-689,560 是一种有效的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂，作用于 GluN1 甘氨酸结合位点。
  36. GC11706 L-701,252 L-701,252 是一种有效的甘氨酸位点 NMDA 受体拮抗剂，IC50 为 420 nM。
  37. GC15732 Synthalin sulfate NMDA receptor antagonist
  38. GC10471 Ifenprodil hemitartrate An NMDA receptor antagonist
  39. GC10237 (±)-1-(1,2-Diphenylethyl)piperidine maleate NMDA receptor antagonist
  40. GC10168 (R)-4-Carboxyphenylglycine NMDA receptor antagonist
  41. GC12488 (RS)-(Tetrazol-5-yl)glycine An NMDA receptor agonist
  42. GC16799 5,7-Dichlorokynurenic acid An NMDA receptor antagonist
  43. GC10370 (S)-(-)-HA-966 (S)-(-)-HA-966 ((-)-HA 966) 是一种 γ-Hydroxybutyrate 样剂，作为 NMDA 受体拮抗剂的活性较弱。
  44. GC14085 (R)-(+)-HA-966 (R)-(+)-HA-966 ((+)-HA-966) 是 N-甲基-D-天冬氨酸 (NMDA) 受体复合物甘氨酸位点的部分激动剂/拮抗剂。
  45. GC14236 (R)-CPP An NMDA receptor antagonist
  46. GC10114 Homoquinolinic acid NMDA receptor agonist
  47. GC11942 cis-ACPD cis-ACPD 是一种有效的 NMDA 受体激动剂，IC50 为 3.3 μM。
  48. GC10476 (RS)-CPP NMDA antagonist
  49. GC15112 D-AP7 NMDA receptor antagonist
  50. GC12154 L-AP5 NMDA拮抗剂
  51. GC17206 DL-AP5 A competitive NMDA antagonist

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