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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for  Endocrinology and Hormones

  1. Cat.No. Product Name Information
  2. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone
  3. GC49838 α-Cortolone A metabolite of cortisol
  4. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
  5. GC60391 β-Casomorphin, bovine TFA β-casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) 是阿片 (opioid) 活性的多肽，与阿片受体结合的 IC50 值为 14 μM。
  6. GC61484 β-Casomorphin, human TFA β-Casomorphin,humanTFA(Humanβ-casomorphin7TFA)是一种阿片样肽，作为opioid受体激动剂。
  7. GC45236 β-Endorphin (rat) β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.
  8. GC38005 β-Endorphin, equine β-Endorphin, equine 为具有镇痛作用的内源性阿片类多肽。
  9. GC38030 β-Endorphin, equine (TFA) β-Endorphin, equine (TFA) 是一种内源性阿片类多肽，对 μ 和 δ 阿片受体 (μ/δ opioid receptors) 有很强的亲和性。具有止痛作用。
  10. GC45238 δ14-Triamcinolone acetonide δ14-Triamcinolone acetonide is a potential impurity found in commercial preparations of triamcinolone acetonide.
  11. GC45239 δ4-Abiraterone δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone.
  12. GC15975 α-Estradiol Endogenous estrogen receptor ligand
  13. GC33736 β-Casomorphin, bovine (β-Casomorphin-7 (bovine)) β-casomorphin,bovine(β-casomorphin-7)是阿片(opioid)活性的多肽，与阿片受体结合的IC50值为14μM。
  14. GC33784 β-Casomorphin, human (Human β-casomorphin 7) β-Casomorphin,human是一种阿片样肽，为opioid受体激动剂。
  15. GC31117 β-Endorphin, human β-Endorphin,human是存在于垂体和下丘脑中的重要的内源性肽，为阿片样(opioid)受体激动剂，尤其对μ-opioid受体和δ-opioid受体的亲和性更高；β-Endorphin,human具有镇痛的功效。
  16. GC45713 (±)-α-Tocopherol Acetate
  17. GC41671 (±)-Equol 4'-sulfate (sodium salt)

    (±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
  18. GC50708 (±)-ML 209
  19. GC64007 (±)-U-50488 hydrate hydrochloride (±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrate hydrochloride 是一种 κ 阿片受体 (κ opioid receptor) 激动剂。
  20. GC15885 (±)-U-50488 hydrochloride

    κ-opioid receptor agonist, selective
  21. GC34960 (+)-Talarozole (+)-Talarozole 是视黄酸代谢的有效抑制剂，来自专利 WO 1997049704 A1。
  22. GC12688 (+)-U-50488 hydrochloride Selective κ-opioid agonist
  23. GC31386 (-)-PX20606 trans isomer ((-)-PX-102 trans isomer) (-)-PX20606transisomer是一种FXR激动剂，在FRET和M1H测定中对于FXR的EC50值分别为18和29nM。
  24. GC15944 (-)-U-50488 hydrochloride κ-opioid receptor agonist, selective
  25. GC34965 (20S)-Protopanaxatriol (20S)-Protopanaxatriol 是人参皂苷的代谢物，通过 glucocorticoid receptor 和 oestrogen receptor 起作用，同时为 LXRα 的抑制剂。
  26. GA20156 (D-Ser(tBu)⁶,Azagly¹⁰)-LHRH (free base)
  27. GA20164 (D-Trp¹²,Tyr³⁴)-pTH (7-34) amide (bovine) The D-Trp¹² substitution leads to a competitive pTH antagonist with increased inhibitory properties in vitro.
  28. GC15373 (E)-2-Decenoic acid Fatty acid identified in royal jelly
  29. GC46336 (E)-Guggulsterone
  30. GC49189 (E/Z)-4-hydroxy Tamoxifen-d5 An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
  31. GC40833 (E/Z)-Endoxifen (E/Z)-Endoxifen is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6.
  32. GC61491 (R)-Bicalutamide (R)-Bicalutamide是Bicalutamide的R型对映体。(R)-Bicalutamide是一种雄激素受体(AR)拮抗剂，具有抗肿瘤活性。(R)-Bicalutamide广泛用于前列腺癌的研究。
  33. GC13373 (R)-DPN estrogen receptor (ER) β agonist
  34. GC30710 (R)-UT-155 (R)-UT-155(compound11)是一种选择性的、雄激素受体降解物(SARD)配体。活性低于S型异构体。
  35. GC18003 (R,R)-THC ERα receptor agonist
  36. GC63292 (rac)-PF-998425 (rac)-PF-998425 是一种有效、选择性的非甾体雄激素受体 (AR) 拮抗剂。(rac)-PF-998425 在 AR 结合和细胞分析中的 IC50 值分别为 26 和 90 nM。(rac)-PF-998425 具有用于研究雄激素性脱发的潜力。
  37. GC49520 (S)-Equol An estrogen receptor β agonist
  38. GC16372 (Z)-4-Hydroxytamoxifen ER modulator, potent and selective
  39. GC62761 1α-Hydroxy-3-epi-vitamin D3 1α-Hydroxy-3-epi-vitamin D3 是 1α，25-二羟基维生素 D3 的天然代谢物，是甲状旁腺激素 (PTH) 分泌的抑制因子。
  40. GC48787 11β-Hydroxyetiocholanolone
  41. GC48710 11-Dehydrocorticosterone
  42. GC49161 16α-hydroxy Dehydroepiandrosterone A metabolite of dehydroepiandrosterone
  43. GC41950 16α-hydroxy Estrone The naturally-occurring estrogens are estrone, estradiol, and estriol.
  44. GC46456 16α-Hydroxyetiocholanolone
  45. GC40454 16(S)-HETE Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
  46. GC49068 16-Epiestriol A metabolite of estrone
  47. GC49848 16-Ketoestradiol An active metabolite of estrone
  48. GC17557 17 alpha-propionate Androgen antagonist
  49. GC41321 17α,20β-Dihydroxy-4-pregnen-3-one An endogenous, maturation-inducing steroid
  50. GC46470 17β-Estradiol-d2
  51. GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane.

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