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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for  Endocrinology and Hormones

  1. Cat.No. 产品名称 Information
  2. GC47698 Mometasone A synthetic glucocorticoid with anti-inflammatory and anti-allergic activities
  3. GC47646 Methiocarb A carbamate pesticide
  4. GC47554 Letrozole-d4 An internal standard for the quantification of letrozole
  5. GC47474 Itraconazole-d5 An internal standard for the quantification of itraconazole
  6. GC47440 Hydrocortisone-d4 An internal standard for the quantification of hydrocortisone
  7. GC47361 Fludioxonil A fungicide
  8. GC47320 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate) A metabolite of ethynyl estradiol
  9. GC47309 Estetrol (hydrate) A naturally occurring estrogen
  10. GC47231 Dimethomorph A morpholine fungicide
  11. GC47215 Dienogest-d8 An internal standard for the quantification of dienogest
  12. GC47168 Daidzein-d4 An internal standard for the quantification of daidzein
  13. GC47159 Cyprodinil An anilinopyrimidine fungicide
  14. GC47097 CJC-1295 A synthetic peptide derivative of GHRH
  15. GC47076 Chenodeoxycholic Acid-d4 An internal standard for the quantification of chenodeoxycholic acid
  16. GC46956 Budesonide-d8 An internal standard for the quantification of budesonide
  17. GC46941 Bombesin (trifluoroacetate salt) A neuropeptide with diverse biological activities
  18. GC46925 Bicalutamide-d4 An internal standard for the quantification of bicalutamide
  19. GC46923 Bexarotene-d4 A neuropeptide with diverse biological activities
  20. GC46909 BE-26263 A fungal metabolite
  21. GC46907 Bazedoxifene-d4 An internal standard for the quantification of bazedoxifene
  22. GC46892 ATRA-BA Hybrid A prodrug form of all-trans retinoic acid and butyric acid
  23. GC46859 Antide (acetate) A GnRHR antagonist
  24. GC46856 Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt) An endogenous angiotensin II fragment
  25. GC46854 Anastrozole-d12 An internal standard for the quantification of anastrozole
  26. GC46827 Aldosterone 21-sulfate (sodium salt) A metabolite of aldosterone
  27. GC46798 Adapalene-d3 An internal standard for the quantification of adapalene
  28. GC46777 AC-262536

    A selective androgen receptor modulator
  29. GC46768 Abaloparatide (acetate) A synthetic derivative of PTHrP and an agonist of PTHR1
  30. GC46740 7β,27-dihydroxy Cholesterol An oxysterol and agonist of RORγ and RORγt
  31. GC46526 21-Deoxycortisol A corticosteroid metabolite of 17-hydroxyprogesterone
  32. GC46470 17β-Estradiol-d2 An internal standard for the quantification of 17β-estradiol
  33. GC46456 16α-Hydroxyetiocholanolone A metabolite of 16α-DHEA and androstenedione
  34. GC46336 (E)-Guggulsterone A farnesoid X receptor antagonist
  35. GC61010 L-Thyroxine sodium A synthetic form of thyroxine
  36. GC61003 Loperamide D6 hydrochloride LoperamideD6hydrochloride(R-18553D6hydrochloride)是Loperamidehydrochloride的氘代化合物。Loperamidehydrochloride是一种阿片受体(opioidreceptor)的激动剂，可用于腹泻的研究。
  37. GC60857 Frakefamide TFA FrakefamideTFA具有有效的止痛作用，是选择性的μ受体的外围激动剂。Frakefamide不能透过血脑屏障，进入中枢神经系统。
  38. GC60731 CTOP TFA CTOPTFA是一种多肽，可以作为μ-opioidreceptor的拮抗剂。
  39. GC60730 CTAP TFA CTAPTFA是一种强效、高选择性的脑渗透类阿片受体(μopioidreceptor）拮抗剂(IC50=3.5nM)，对δopioid受体(IC50=4500nM)和生长抑素受体具有超过1200倍的选择性。CTAPTFA可用于L-多巴胺诱导的运动障碍(LID)的研究。
  40. GC60589 Apalutamide D4 ApalutamideD4(ARN-509D4)是Apalutamide的一种氘代化合物。Apalutamide是有效，竞争性的雄激素受体(AR)拮抗剂，IC50为16nM。
  41. GC60391 β-Casomorphin, bovine TFA β-casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) 是阿片 (opioid) 活性的多肽，与阿片受体结合的 IC50 值为 14 μM。
  42. GC60076 Bigelovin Bigelovin是可从海百合中分离得到的一种倍半萜内酯，是选择性的视黄素X受体α(retinoidXreceptorα)的激动剂。Bigelovin可通过诱导凋亡和自噬来发挥抗肿瘤活性。Bigelovin通过抑制ROS的生成来调节mTOR信号通路。
  43. GC39619 SB-612111 SB-612111 是一种新型高效的人阿片受体孤儿受体 (ORL-1) 拮抗剂，对 hORL-1 具有较高的亲和力 (Ki=0.33 nM)。SB-612111 对 μ-，κ- 和 δ-receptor 的 Ki 值分别为 57.6 nM，160.5 nM 和 2109 nM。SB-612111 能有效拮抗 Nociceptin 在急性疼痛模型中的造成的痛觉作用。
  44. GC39584 AGN194204 AGN194204 (IRX4204) 是一种具有口服活性的，选择性 RXR 激动剂，对 RXRα，RXRβ 和 RXRγ 的 Kd 值分别为 0.4 nM，3.6 nM 和 3.8 nM，EC50 分别为 0.2 nM，0.8 nM 和 0.08 nM。AGN194204 对 RAR 无活性，并具有抗炎和抗癌作用。
  45. GC39451 Testosterone (propionate) An Analytical Reference Standard
  46. GC50558 TAN 452

    TAN 452 是一种具有口服活性的选择性外周作用 δ-阿片受体 (DOR) 拮抗剂，Ki 为 0.47nM，Kb 为 0.21nM。
  47. GC50491 PF 04449913 maleate A Smo antagonist
  48. GC50438 SAG dihydrochloride An agonist of Smoothened
  49. GC50279 MK 386 Potent, selective human type 1 5α-reductase inhibitor
  50. GC50201 IHR 1 IHR 1 是一种细胞膜不可渗透的 Smo 拮抗剂。
  51. GC50178 DPC AJ1951 A peptide PPR agonist

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