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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for  Endocrinology and Hormones

  1. Cat.No. 产品名称 Information
  2. GC62124 UT-34 UT-34 is a potent, selective and orally bioavailable second-generation androgen receptor (AR) pan antagonist and degrader with IC50 of 203.46 nM, 80.78 nM and 94.17 nM for wild-type, T877A and W741L AR, respectively. UT-34 is a potential next-generation therapeutic for enzalutamide-resistant prostate cancer.
  3. GC62118 ARV-110 Bavdegalutamide (ARV-110) is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR. ARV-110 completely degrades androgen receptor (AR) in all cell lines tested with DC50 of < 1 nM. ARV-110 can be used for the research of prostate cancer.
  4. GC62106 JNJ-63576253 JNJ-63576253 (TRC-253) is a potent and selective androgen receptor (AR) Antagonist with IC50 of 6.9 nM. JNJ-63576253 displays robust inhibition in WT and LBD-mutated, enzalutamide-resistant models of prostate cancer.
  5. GC61954 Deltorphin 2 TFA Deltorphin 2 TFA 是一种选择性的 δ 阿片受体肽激动剂。
  6. GC61850 Medroxyprogesterone acetate D3 Medroxyprogesterone acetate D3 是 Medroxyprogesterone acetate 的氘代物。Medroxyprogesterone acetate 是一种广泛使用的合成类固醇，与孕酮 (progesterone)，雄激素 (androgen) 和糖皮质激素受体 (glucocorticoid receptors) 都有作用。
  7. GC61586 UFP-101 TFA UFP-101TFA是一种强效、选择性和竞争性的NOP受体拮抗剂，pKi为10.24。UFP-101TFA对δ、μ和κ类阿片受体的选择性大于3000倍。UFP-101TFA具有抗抑郁药样作用。
  8. GC61491 (R)-Bicalutamide (R)-Bicalutamide是Bicalutamide的R型对映体。(R)-Bicalutamide是一种雄激素受体(AR)拮抗剂，具有抗肿瘤活性。(R)-Bicalutamide广泛用于前列腺癌的研究。
  9. GC61484 β-Casomorphin, human TFA β-Casomorphin,humanTFA(Humanβ-casomorphin7TFA)是一种阿片样肽，作为opioid受体激动剂。
  10. GC61481 PROTAC AR Degrader-4 TFA PROTACARDegrader-4包含cIAP1配体结合基团，linker和雄激素受体(AR)配体结合基团。基于cIAP1的降解剂也被称为SNIPER。
  11. GC61397 Asimadoline hydrochloride A potent κ-opioid receptor agonist
  12. GC48937 L-Tyrosine-13C9,15N An internal standard for the quantification of L-tyrosine
  13. GC48910 2-Hydroxyanthraquinone An anthraquinone with antibacterial and estrogenic activities
  14. GC48880 7-Methoxyflavone A flavone with diverse biological activities
  15. GC48831 Flutamide-d7 Flutamide-d7 是氘标记的氟他胺。
  16. GC48824 4-hydroxy Estrone A metabolite of estrone
  17. GC48819 17-Epiestriol A metabolite of estrone
  18. GC48808 5β-Androstane-3α,17β-diol A metabolite of testosterone
  19. GC48803 Norethynodrel A synthetic progestin
  20. GC48788 Norethindrone-d6 An internal standard for the quantification of norethindrone
  21. GC48787 11β-Hydroxyetiocholanolone A metabolite of hydrocortisone
  22. GC48763 Gestodene-d6 An internal standard for the quantification of gestodene
  23. GC48724 Pregnanetriol A metabolite of 17α-hydroxyprogesterone
  24. GC48710 11-Dehydrocorticosterone An endogenous mineralocorticoid
  25. GC48649 7-hydroxy Chlorpromazine (hydrochloride) An active metabolite of chlorpromazine
  26. GC48610 GSK3987 A dual agonist of LXRα and LXRβ
  27. GC48595 Chenodeoxycholic Acid MaxSpec® Standard A primary bile acid
  28. GC48496 Clobetasol Propionate-d5 An internal standard for the quantification of clobetasol propionate
  29. GC48432 KB-130015 An antiarrhythmic agent
  30. GC48426 CAY10771 A dual agonist of FXR and PPARδ
  31. GC48424 Chenodeoxycholic Acid 24-Acyl-β-D-Glucuronide A metabolite of CDCA
  32. GC48395 3,3',5-Triiodo-L-thyronine (sodium salt hydrate) A thyroid hormone
  33. GC48358 Thymulin (acetate hydrate) A peptide hormone
  34. GC48348 Carbetocin (acetate) A peptide oxytocin receptor agonist
  35. GC48328 Obestatin (human) (trifluoroacetate salt) A peptide hormone
  36. GC48327 Secretin (rat) (trifluoroacetate salt) A neuropeptide hormone
  37. GC50708 (±)-ML 209 An RORγt antagonist
  38. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A peptide hormone
  39. GC48219 Ulipristal Acetate-d6 An internal standard for the quantification of ulipristal acetate
  40. GC48174 Thiorphan-d5 An internal standard for the quantification of thiorphan
  41. GC48023 Raloxifene-d4 (hydrochloride) An internal standard for the quantification of raloxifene
  42. GC47982 Propylthiouracil-d5 An internal standard for the quantification of propylthiouracil
  43. GC47979 Propiconazole-d7 An internal standard for the quantification of propiconazole
  44. GC47976 Progesterone-d9 An internal standard for the quantification of progesterone
  45. GC47973 PRGL493 An ACSL4 inhibitor
  46. GC47969 Precocene II A chromene with anti-juvenile hormone activity
  47. GC47925 Pasireotide (aspartate) (trifluoroacetate salt) A somatostatin receptor agonist
  48. GC47824 Olmesartan Medoxomil-d6 An internal standard for the quantification of olmesartan medoxomil
  49. GC47797 Norgestimate-d6 An internal standard for the quantification of norgestimate
  50. GC47769 Neuropeptide S (human) (acetate) A neuropeptide NSPR agonist
  51. GC47747 Napyradiomycin A1 A fungal metabolite with diverse biological activities

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