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CRTH2(在 T-Helper 2 型细胞上表达的趋化受体同源分子)

CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.

  1. Cat.No. 产品名称 Information
  2. GC12434 AZD1981 AZD1981 是一种有效的选择性 CRTh2 拮抗剂;以高效力 (pIC50 = 8.4) 从人重组 DP2 中置换放射性标记的 PGD2。

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