Metabolism(代谢)
- PPAR(203)
- 5-alpha Reductase(10)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(10)
- Aminopeptidase(14)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(52)
- CETP(9)
- Cholesterol absorption(1)
- CPT1(2)
- CYP3A/CYP450(18)
- Dehydrogenase(40)
- DHFR(6)
- DGAT(7)
- Dopamine β-hydroxylase(10)
- Enolase(4)
- FAAH(35)
- Factor Xa(57)
- Ferroptosis(183)
- Folate Analogue(2)
- Glucokinase(17)
- HMG-CoA Reductase(37)
- HSP(92)
- IDO(46)
- KRAS-PDEδ(3)
- MAO(6)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(23)
- P450(436)
- PDE(234)
- Phospholipase(128)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(18)
- SGLT(28)
- TPH(4)
- Transferase(26)
- ALP(1)
- Carbohydrates(32)
- Transaminase(3)
- Glutathione Reductase(1)
- Catalase(10)
- monooxygenase(1)
- PKM2(1)
- Aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(17)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(101)
- Pyruvate kinase(12)
- Others(64)
- MGL(1)
- Galactosidase(2)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(8)
- Dihydroorotate Dehydrogenase(13)
- Bile Acids & Microbiome(118)
- Bone Growth & Remodeling(52)
- Carbohydrate Metabolism(160)
- Cofactors & Vitamins(83)
- Dyslipidemias(99)
- Inborn Errors of Metabolism(97)
- Metabolic Syndrome(21)
- Necroptosis(10)
- Necrosis(17)
- Nutrient Sensing(14)
- Phosphodiesterase(33)
- Reproductive Biology(174)
- Thermogenesis(9)
- Sterol Biosynthesis(40)
- Prolyl Hydroxylation Enzymes(2)
- Biliary System(11)
- Metabolic Disease(5)
- Fat Mass and Obesity-associated Protein (FTO)(4)
- SHIP(1)
- Cat.No. 产品名称 Information
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GC91791
Cholic Acid 3-sulfate (potassium salt)
3-Sulfocholate,3-Sulfocholic Acid
Cholic acid 3-sulfate is a metabolite of the primary bile acid cholic acid . - GC91783 FA16 FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.
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GC91775
h-e5'NT Inhibitor 5C
Human Ecto-5'-nucleotidase Inhibitor 5C
h-e5'NT Inhibitor 5C is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (IC50s = 0.37 and 1.66 µM for the human and rat enzymes, respectively). - GC91773 18-hydroxy Oleoyl Leucine-d7 18-hydroxy Oleoyl leucine-d7 is intended for use as an internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS.
- GC91768 GSK205 (hydrobromide) GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels).
- GC91767 ENPP3 Inhibitor 5J ENPP3 inhibitor 5J is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) and ENPP3 (IC50s = 0.59 and 0.62 µM, respectively, for the human enzymes).
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GC91761
ABBV-CLS-484 (hydrochloride)
Osunprotafib
ABBV-CLS-484 is a dual inhibitor of protein tyrosine phosphatase 1N (PTP1N) and PTP2N (IC50s = 2.5 and 1.8 nM, respectively). -
GC91705
Etomidate-d5
(+)-Etomidate-d5,d-Etomidate-d5,(R)-Etomidate-d5
Etomidate-d5 is intended for use as an internal standard for the quantification of etomidate by GC- or LC-MS. -
GC91691
viFSP1
Versatile Inhibitor of Ferroptosis Suppressor Protein 1,Versatile Inhibitor of FSP1
viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively). - GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).
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GC91667
NSC 44625
Bendroflumethiazide Impurity A,2,4-Disulfamyl-5-trifluoromethylaniline
NSC 44625 is an inhibitor of carbonic anhydrase II (CAII; Ki = 63 nM for the human enzyme). - GC91641 4-Hydroxy-1-(2-phenylethyl)piperidine 4-Hydroxy-1-(2-phenylethyl)piperidine is a building block that has been used in the synthesis of ligands of the muscarinic acetylcholine receptor (mAChR) or sigma non-opioid intracellular receptor 1 (σ1 receptor).
- GC91623 Ferroptosis Inducer 24 Ferroptosis inducer 24 is an inducer of ferroptosis.
- GC91613 FerroLOXIN-1 FerroLOXIN-1 is an inhibitor of the 15-lipoxygenase-2 (15-LO-2) and phosphatidylethanolamine-binding protein 1 (PEBP1) catalytic complex.
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GC91598
GPX4 16
Glutathione Peroxidase 4 16
GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4). - GC91548 Rosuvastatin EP Impurity A (calcium salt) Rosuvastatin EP impurity A is a potential impurity in commercial preparations of the HMG-CoA reductase inhibitor rosuvastatin.
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GC91547
Tanzawaic Acid B
(+)-Tanzawaic Acid B
Tanzawaic acid B is a fungal metabolite that has been found in Penicillium and has diverse biological activities. -
GC91543
(E/Z)-Droloxifene
3-Hydroxytamoxifen
(E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene. - GC91499 Voriconazole-d3 N-oxide Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide by GC- or LC-MS.
- GC91492 Propiverine N-oxide Propiverine N-oxide is an active metabolite of the muscarinic acetylcholine receptor antagonist propiverine .
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GC91489
Chondroitin Sulfate A (sodium salt)
Chondroitin-4-sulfate,CSA
Chondroitin sulfate A (CSA) is a glycosaminoglycan. -
GC91486
D-(+)-Ribonic Acid γ-lactone
NSC 1031
D-(+)-Ribonic acid γ-lactone is an oxidized derivative of ribose and a synthetic material. -
GC26431
Pentacosafluorotridecanoic Acid
全氟十三烷酸,PFTrDA
Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant.
- GC72637 Hexadecanoate-13C16 potassium Hexadecanoate-13C16 potassium是13C标记的十六烷酸钠。
- GC72527 S-(-)-Warfarin
- GC72482 Theodrenaline hydrochloride Theodrenaline hydrochloride是一种心脏兴奋剂,也与Cafedrine一起作为降压药。
- GC72481 Naveglitazar Naveglitazar(LY519818)是一种非噻唑烷二酮过氧化物酶体增殖物激活受体(PPAR)α-γ双γ显性激动剂,在动物模型中显示出降低血糖的潜力。
- GC72438 Osocimab Osocimab (BAY 1213790),抗fxia抗体(Ki=2.4 nM;EC50 = 0.2海里)。
- GC72222 Survodutide Survodutide(BI 456906)是一种强效的选择性胰高血糖素受体/GLP-1受体(GCGR/GLP-1R)双重激动剂,在CHO-K1细胞中的EC50分别为0.52 nM和0.33 nM。
- GC72096 Bamadutide Bamadutide(SAR425899)是一种强效的双胰高血糖素样肽-1受体/胰高血糖激素受体激动剂。
- GC72078 Azadiradione Azadiradione是在印度印楝中发现的一种生物活性类柠檬素。
- GC72068 Batatasin IV Batatasin IV是一种具有抗炎活性的LTA4H抑制剂。
- GC72026 Sclareol glycol Sclareol glycol是氨溴化酶的前体。
- GC71865 Palmitic acid-13C2 Palmitic acid-13C2是13C标记的棕榈酸。
- GC71863 Palmitic acid-13C16 sodium Palmitic acid-13C16 sodium是13C标记的棕榈酸钠。
- GC71840 L-Cystine-34S2 L-Cystine-34S2是34S标记的L-胱氨酸。
- GC71839 L-Cystine-d4 L-Cystine-d4是氘标记的L-胱氨酸。
- GC71837 L-Glutamine-13C5,15N2,d5 L-Glutamine-13C5,15N2,d5是氘、13C-和15-标记的L-谷氨酰胺。
- GC71789 ZY-1 ZY-1是ZY-2的控制分子。
- GC71730 L-Glutathione reduced-13C2,15N L-Glutathione reduced-13C2,15N13C和15N标记的L-谷胱甘肽是否减少。
- GC71605 Doxofylline-d6 Doxofylline-d6是氘标记的多索茶碱。
- GC71583 Dechloro Rivaroxaban Dechloro Rivaroxaban是一种高度选择性、口服活性的Xa因子抑制剂。
- GC71580 Otamixaban hydrochloride Otamixaban hydrochloride是一种强效、选择性、速效、竞争性和可逆的fXa抑制剂(Ki=0.5 nM),可有效抑制游离和凝血酶原酶结合的fXa。
- GC71535 Fuzapladib Fuzapladib(IS-741)是一种口服活性白细胞功能相关抗原1型(LFA-1)活化抑制剂,是一种白细胞粘附分子。
- GC71531 Ciraparantag acetate Ciraparantag acetate是凝血酶和Xa因子抑制剂。
- GC71502 CA/MAO-B-IN-1 CA/MAO-B-IN-1(化合物78)是人脑碳酸酐酶(CA)和单胺氧化酶-B(MAO-B)的双重抑制剂,IC50分别为8.8和7.0 nM。
- GC71498 Carbonic anhydrase inhibitor 16 Carbonic anhydrase inhibitor 16(化合物1)是一种登革热蛋白酶抑制剂,对碳酸酐酶hCA I和hCA II具有抑制活性(Ki:28.5 nM,2.2 nM)。
- GC71411 Dasatinib analog-1 Dasatinib analog-1(化合物5826)抑制CYP3A4的活性,Ki值为5.4μM。
- GC71393 Opevesostat Opevesostat是一种胆固醇侧链裂解酶(CYP11A1)抑制剂。
- GC71367 PPARγ-IN-2 PPARγ-IN-2(化合物5a)是PPARγ抑制剂。