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Aromatase(芳香酶)

Aromatase is an enzyme which belongs to the cytochrome p450 superfamily. It localizes on the endoplasmic reticulum of estrogen producing cell and catalyzes the final step of estrogen biosynthesis, converting androgen to estrogens.

  1. Cat.No. 产品名称 Information
  2. GC63755 Exemestane-D2 Exemestane-D2 (FCE 24304-D2) 是 Exemestane 的氘代物。Exemestane (FCE 24304) 是一种选择性,不可逆和具有口服活性的甾体芳香酶 (aromatase) 抑制剂,对人胎盘和大鼠卵巢芳香酶的 IC50 分别为 30 nM 和 40 nM。Exemestane 可用于激素依赖性乳腺癌研究。
  3. GC38682 Flavanone Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one) show strong antioxidant and radical scavenging activity, and appear to be associated with a reduced risk of certain chronic diseases, the prevention of some cardiovascular disorders, and certain kinds of cancer. Flavanones also exhibit antiviral, antimicrobial, and anti-inflammatory activities, beneficial effects on capillary fragility, and an ability to inhibit human platelet aggregation, anti-ulcer, and anti-allergenic properties.
  4. GC19151 Fadrozole A non-steroidal aromatase inhibitor
  5. GC18301 Fadrozole (hydrochloride) A non-steroidal aromatase inhibitor
  6. GC12890 α-Naphthoflavone A flavone that modulates xenobiotic metabolism
  7. GC12140 Endoxifen Endoxifen Z-异构体是最重要的他莫昔芬代谢物,负责在表达雌激素受体-α (ERα) 的乳腺癌细胞中引发该药物的抗雌激素作用。
  8. GC12815 Formestane An Analytical Reference Standard
  9. GC16433 Aminoglutethimide An aromatase inhibitor
  10. GC10256 Anastrozole An aromatase/CYP19A1 inhibitor
  11. GC10726 Letrozole An aromatase inhibitor
  12. GC11813 Exemestane A third generation, irreversible steroidal aromatase inhibitor
  13. GN10457 Oleuropein A polyphenol

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