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TRP Channel(瞬时受体电位离子通道)

TRP (transient receptor potential) channels are a family of cation channels that sense various external and celluar signals such as mechanical stress, temperature, cellular messengers and exogenous chemicals. It is implicated in vascular tone , neurological disorders, kidney diseases, hypomagnesemia and hypocalcemia etc.

  1. Cat.No. 产品名称 Information
  2. GC67924 Dihydrocapsiate
  3. GC67784 ML-SI3
  4. GC67739 D-erythro-Sphingosine hydrochloride
  5. GC66436 FEMA 4809
  6. GC66016 Evifacotrep
  7. GC65611 AMG 333 A TRPM8 antagonist
  8. GC65536 TRPV4 agonist-1
  9. GC65211 Umbellulone
  10. GC65106 Pregnenolone-d4-1
  11. GC65006 JNc-440
  12. GC64852 Tivanisiran
  13. GC64573 PF-04745637
  14. GC64459 Englerin A
  15. GC64086 TRPM8 antagonist 3
  16. GC64062 (1R,2R)-ML-SI3
  17. GC63249 Vanilloid receptor antagonist 1
  18. GC63244 TRPV4 agonist-1 free base
  19. GC62179 Cyclic ADP-ribose An endogenous Ca2+ mobilizer
  20. GC61792 Cyclic ADP-ribose ammonium An endogenous Ca2+ mobilizer
  21. GC19729 Adenosine 5′-diphosphoribose sodium Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种烟酰胺腺嘌呤核苷酸 (NAD+) 代谢物。
  22. GC50670 D-GsMTx4 TRPC1/6 and Piezo2 inhibitor
  23. GC50667 SET 2 TRPV2 (transient receptor potential vanilloid type 2) antagonist (IC50 = 0
  24. GC60542 8-Gingerol A natural TRPV1 agonist
  25. GC50641 IA-Alkyne IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) 是一种 TRP 通道 (TRPC) 激动剂,具有研究呼吸道感染的潜力。
  26. GC50640 OptoBI-1 OptoBI-1 是一种光致变色 TRPC3 激动剂,可作为一种光药理学工具来控制神经元放电。
  27. GC50617 BTD Selective TRPC5 activator
  28. GC50590 TRPC6-PAM-C20 TRPC6-PAM-C20 是 TRPC6 通道的选择性正变构调节剂 (PAM)。
  29. GC50557 CBA A TRPM4 inhibitor
  30. GC50475 AM 12 TRPC5 inhibitor
  31. GC50268 M 084 hydrochloride TRPC4/5 channel blocker; antidepressant and anxiolytic
  32. GC50261 A 425619 Potent TRPV1 antagonist
  33. GC50188 CIM 0216 A TRPM3 channel activator
  34. GC50115 ASP 7663 A TRPA1 agonist
  35. GC50058 AMG 21629 Potent and selective TRPV1 antagonist
  36. GC39198 GSK1702934A A TRPC3 and TRPC6 activator
  37. GC46199 PF-05105679 A TRPM8 antagonist
  38. GC39117 Methyl syringate Methyl syringate (Syringic Acid Methyl Ester), a plant phenolic compound, is a specific and selective TRPA1 agonist.
  39. GC38726 1,4-Cineole 1,4-Cineole (Isocineole) is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in eucalyptus oil, activates both human TRPM8 and human TRPA1.
  40. GC34489 BI-749327
  41. GC45907 RN-9893 (hydrochloride) A TRPV4 antagonist
  42. GC38501 GSK205
  43. GC38465 GsMTx4

    GsMTx4 是一种蜘蛛毒液肽,选择性地抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透的机械敏感性通道(MSCs)。GsMTx4 是一种重要的药理学工具,用于鉴定兴奋性 MSCs 在正常生理学和病理学中的作用。GsMTx4 显着减弱膀胱机能亢进。

  44. GC37831 TRPM8 agonist WS-3 Cyclohexanecarboxamide (Ethyl menthane carboxamide, WS3, Hexahydrobenzamide) is a cooling agent and an agonist at TRPM8 receptors (EC50 = 3.7 μM).
  45. GC37655 SN 2
  46. GC36627 ML204 hydrochloride A selective TRPC4 channel blocker
  47. GC36609 Mifamurtide
  48. GC36277 Hydroxy-α-sanshool
  49. GC35970 EIPA hydrochloride
  50. GC35501 Beta-Eudesmol A sesquiterpene with diverse biological activities
  51. GC35407 Asivatrep

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