TRP Channel(瞬时受体电位离子通道)
TRP (transient receptor potential) channels are a family of cation channels that sense various external and celluar signals such as mechanical stress, temperature, cellular messengers and exogenous chemicals. It is implicated in vascular tone , neurological disorders, kidney diseases, hypomagnesemia and hypocalcemia etc.
- Cat.No. 产品名称 Information
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GC67924
Dihydrocapsiate
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GC67784
ML-SI3
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GC67739
D-erythro-Sphingosine hydrochloride
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GC66436
FEMA 4809
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GC66016
Evifacotrep
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GC65611
AMG 333
A TRPM8 antagonist
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GC65536
TRPV4 agonist-1
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GC65211
Umbellulone
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GC65106
Pregnenolone-d4-1
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GC65006
JNc-440
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GC64852
Tivanisiran
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GC64573
PF-04745637
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GC64459
Englerin A
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GC64086
TRPM8 antagonist 3
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GC64062
(1R,2R)-ML-SI3
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GC63249
Vanilloid receptor antagonist 1
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GC63244
TRPV4 agonist-1 free base
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GC62179
Cyclic ADP-ribose
An endogenous Ca2+ mobilizer
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GC61792
Cyclic ADP-ribose ammonium
An endogenous Ca2+ mobilizer
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GC19729
Adenosine 5′-diphosphoribose sodium
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种烟酰胺腺嘌呤核苷酸 (NAD+) 代谢物。
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GC50670
D-GsMTx4
TRPC1/6 and Piezo2 inhibitor
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GC50667
SET 2
TRPV2 (transient receptor potential vanilloid type 2) antagonist (IC50 = 0
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GC60542
8-Gingerol
A natural TRPV1 agonist
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GC50641
IA-Alkyne
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) 是一种 TRP 通道 (TRPC) 激动剂,具有研究呼吸道感染的潜力。
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GC50640
OptoBI-1
OptoBI-1 是一种光致变色 TRPC3 激动剂,可作为一种光药理学工具来控制神经元放电。
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GC50617
BTD
Selective TRPC5 activator
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GC50590
TRPC6-PAM-C20
TRPC6-PAM-C20 是 TRPC6 通道的选择性正变构调节剂 (PAM)。
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GC50557
CBA
A TRPM4 inhibitor
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GC50475
AM 12
TRPC5 inhibitor
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GC50268
M 084 hydrochloride
TRPC4/5 channel blocker; antidepressant and anxiolytic
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GC50261
A 425619
Potent TRPV1 antagonist
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GC50188
CIM 0216
A TRPM3 channel activator
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GC50115
ASP 7663
A TRPA1 agonist
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GC50058
AMG 21629
Potent and selective TRPV1 antagonist
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GC39198
GSK1702934A
A TRPC3 and TRPC6 activator
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GC46199
PF-05105679
A TRPM8 antagonist
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GC39117
Methyl syringate
Methyl syringate (Syringic Acid Methyl Ester), a plant phenolic compound, is a specific and selective TRPA1 agonist.
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GC38726
1,4-Cineole
1,4-Cineole (Isocineole) is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in eucalyptus oil, activates both human TRPM8 and human TRPA1.
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GC34489
BI-749327
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GC45907
RN-9893 (hydrochloride)
A TRPV4 antagonist
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GC38501
GSK205
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GC38465
GsMTx4
GsMTx4 是一种蜘蛛毒液肽,选择性地抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透的机械敏感性通道(MSCs)。GsMTx4 是一种重要的药理学工具,用于鉴定兴奋性 MSCs 在正常生理学和病理学中的作用。GsMTx4 显着减弱膀胱机能亢进。
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GC37831
TRPM8 agonist WS-3
Cyclohexanecarboxamide (Ethyl menthane carboxamide, WS3, Hexahydrobenzamide) is a cooling agent and an agonist at TRPM8 receptors (EC50 = 3.7 μM).
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GC37655
SN 2
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GC36627
ML204 hydrochloride
A selective TRPC4 channel blocker
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GC36609
Mifamurtide
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GC36277
Hydroxy-α-sanshool
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GC35970
EIPA hydrochloride
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GC35501
Beta-Eudesmol
A sesquiterpene with diverse biological activities
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GC35407
Asivatrep