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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

TRP Channel(瞬时受体电位离子通道)

TRP (transient receptor potential) channels are a family of cation channels that sense various external and celluar signals such as mechanical stress, temperature, cellular messengers and exogenous chemicals. It is implicated in vascular tone , neurological disorders, kidney diseases, hypomagnesemia and hypocalcemia etc.

Products for  TRP Channel

  1. Cat.No. 产品名称 Information
  2. GC16917 GSK 2193874 A TRPV4 channel antagonist
  3. GC11701 A 967079 A potent inhibitor of the TRPA1 channel
  4. GC12260 HC 067047 A selective TRPV4 antagonist
  5. GC14537 AMTB hydrochloride A TRPM8 antagonist
  6. GC11185 TCS 5861528 A TRPA1 channel blocker
  7. GC14276 BCTC A potent TRPV1 antagonist
  8. GC14649 Pyr3 A TRPC3 inhibitor
  9. GC17267 RN 1734 A TRPV4 antagonist
  10. GC15346 RN 1747 RN 1747 是一种选择性瞬时受体电位阳离子通道亚家族 V 成员 4 (TRPV4) 激动剂，对 hTRPV4、mTRPV4 和 rTRPV4 的 EC50 值分别为 0.77 μM、4.0 μM 和 4.1 μM。
  11. GC13994 Phenamil A TRPP3 inhibitor
  12. GC15893 EIPA A selective inhibitor of Na+/H+ exchangers
  13. GC15427 JNJ 17203212 A TRPV1 antagonist
  14. GC18020 AP 18 A reversible channel blocker of TRPA1
  15. GC14248 SB 452533 SB 452533 是一种有效的选择性 TRPV1 拮抗剂，pKb 为 7.8。
  16. GC12580 Polygodial A natural antifungal sesquiterpene
  17. GC16760 WS 12 A TRPM8 agonist
  18. GC14387 WS 3 A non-specific proliferative molecule
  19. GC18069 Cardamonin A chalconoid with anti-inflammatory and anti-tumor activity
  20. GC11926 AMG 9810 A TRPV1 antagonist
  21. GC17879 OLDA A synthetic endocannabinoid analog and potent 5-lipoxygenase inhibitor
  22. GC14997 SB 366791 A TRPV1 antagonist
  23. GC17562 2-APB

    2-APB是一种Ins(1,4,5)P3受体拮抗剂，InsP3浓度为100 nm时，其IC50值为42μM。2-APB也是一种TRPV 6抑制剂和多种TRP通道的调节剂。
  24. GC14641 SKF 96365 hydrochloride An inhibitor of voltage-gated calcium channels
  25. GC16467 Olvanil A structural analog of capsaicin
  26. GC12520 Diphenyleneiodonium chloride A NOX inhibitor
  27. GC11906 Ononetin A deoxybenzoin with diverse biological activities
  28. GC10873 α-Spinasterol A TRPV1 antagonist
  29. GC11613 L-R4W2 L-R4W2 是香草素受体 1 (VR1, TRPV1) 的有效拮抗剂，IC50 为 0.1 μM。
  30. GC10221 9-Phenanthrol A TRPM4 inhibitor
  31. GC15417 STEARDA potentiates TRPV1-mediated effects of NADA
  32. GC16700 PALDA A naturally-occurring N-acyl dopamine
  33. GC10188 6'-Iodoresiniferatoxin TRPV1 (VR1) vanilloid receptor partial agonist
  34. GC11293 PPAHV

    vanilloid TRPV1 (VR1) receptor agonist
  35. GC16801 5'-Iodoresiniferatoxin TRPV1 (VR1) receptor antagonist
  36. GC12783 Resiniferatoxin

    Resiniferatoxin是一种选择性 TRPV1 受体激动剂，以不可逆的方式激活TRPV1。
  37. GC12769 Nonivamide A TRPV1 agonist
  38. GC16825 Probenecid An inhibitor of OATs and MRP1 and an agonist of TRPV2
  39. GC13218 TRPC6 inhibitor A TRPC6 channel blocker
  40. GC15947 HC-030031 Selective TRPA1 channel blocker
  41. GC16882 Icilin An agonist of CMR1/TRPM8
  42. GC14580 SB705498 A TRPV1 antagonist
  43. GC13003 AMG-517 A TRPV1 antagonist
  44. GC17918 Capsazepine A TRPV1 antagonist
  45. GC14065 Capsaicin A terpene alkaloid with diverse biological activities
  46. GC16444 Rosiglitazone

    A PPARγ agonist
  47. GC11318 Rosiglitazone maleate A PPARγ agonist
  48. GN10437 Imperatorin A furanocoumarin with diverse biological activities
  49. GN10792 Caffeic acid An inhibitor of 5-LO
  50. GN10007 8-Gingerol A natural TRPV1 agonist

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