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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Sodium Channel(钠离子通道)

Sodium channel are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell plasma membrane.

  1. Cat.No. 产品名称 Information
  2. GC26033 Veratrine Veratridine (Cevadine, Cevadin, Cevadene), a steroidal alkaloid found in plants of the lily family, is a voltage-gated sodium channel activator. Veratridine induces anxiogenic-like behaviors in rats.
  3. GC25936 SLC13A5-IN-1 SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5/NaCT). It completely blocks the uptake of 14 C-citrate and has the potential for the treatment of metabolic and/or cardiovascular diseases.
  4. GC25812 Quinidine sulfate Quinidine (Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.
  5. GC25134 Benzocaine hydrochloride Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
  6. GC67949 GNE-0439
  7. GC67799 PF-05198007
  8. GC66038 PF-06649298
  9. GC65940 Zandatrigine
  10. GC65593 6-Benzoylheteratisine
  11. GC65531 Hardwickiic acid
  12. GC65416 Flecainide Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.
  13. GC65320 Nav1.7-IN-3
  14. GC65272 APETx2 TFA
  15. GC65231 N-Bromoacetamide
  16. GC65150 Flecainide hydrochloride
  17. GC64691 RY796
  18. GC64658 Bliretrigine
  19. GC64206 GDC-0310
  20. GC64113 Lamotrigine-13C3,d3
  21. GC64072 NBI-921352
  22. GC63821 S-Bioallethrin
  23. GC63799 AZ194
  24. GC63295 Ranolazine-d8
  25. GC63261 XPC-6444
  26. GC63259 VX-150 VX-150 (EOS-62073) is an orally bioavailable pro-drug that rapidly converts into its active moiety, which is a highly selective inhibitor of NaV1.8 relative to the other sodium channel subtypes (>400-fold).
  27. GC63234 TPC2-A1-P
  28. GC63108 NHE3-IN-2
  29. GC63063 Mebeverine hydrochloride Mebeverine (Duspatalin, Duspatal, Colofac), a 3-phenylethylamine derivative of methoxybenzamine, acts as a musculotropic antispasmodic agent.
  30. GC62739 (R)-Funapide
  31. GC61594 Lu AE98134
  32. GC50707 GX 201 GX 201 是一种选择性 NaV1.7 抑制剂，对 hNaV1.7 的 IC50 \u003c3.2 nM。
  33. GC47155 Cyfluthrin A pyrethroid insecticide
  34. GC61250 Ropivacaine Ropivacaine is a member of the amino amide class of local anesthetics.
  35. GC61175 PF-06305591 dihydrate
  36. GC61110 Nav1.1 activator 1
  37. GC61046 Methocarbamol D5 An internal standard for the quantification of methocarbamol
  38. GC60642 Bifenthrin A synthetic pyrethroid insecticide
  39. GC39843 Ropivacaine mesylate
  40. GC39792 Halazone Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water.
  41. GC39719 Nigericin

    A potassium ionophore
  42. GC39618 Mexiletine D6 hydrochloride
  43. GC50299 OD1 Potent hNav1.4, rNav1.6 and rNav1.7 channel activator
  44. GC50264 ProTx III Potent Nav1.7 blocker; analgesic
  45. GC50198 Topiramate - d12 An internal standard for the quantification of topiramate
  46. GC50174 QAQ dichloride QAQ dichloride 是一种可光开关的电压门控 Nav 和 Kv 通道阻断剂，可阻断其反式（偶氮苯光电开关）的通道，但不阻断其顺式形式。
  47. GC50071 NAV 26 NAV 26 (compound 26) 是一种选择性电压门控钠通道 Nav1.7 阻滞剂，IC50 为 0.37 μM。
  48. GC45985 (±)-Indoxacarb A broad-spectrum insecticide
  49. GC38872 Zoniporide hydrochloride hydrate
  50. GC38865 Tocainide hydrochloride
  51. GC38484 Dimethyl lithospermate B

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