Sodium Channel(钠离子通道)
Sodium channel are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell plasma membrane.
- Cat.No. 产品名称 Information
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GC26033
Veratrine
Veratridine (Cevadine, Cevadin, Cevadene), a steroidal alkaloid found in plants of the lily family, is a voltage-gated sodium channel activator. Veratridine induces anxiogenic-like behaviors in rats.
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GC25936
SLC13A5-IN-1
SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5/NaCT). It completely blocks the uptake of 14 C-citrate and has the potential for the treatment of metabolic and/or cardiovascular diseases.
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GC25812
Quinidine sulfate
Quinidine (Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.
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GC25134
Benzocaine hydrochloride
Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
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GC67949
GNE-0439
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GC67799
PF-05198007
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GC66038
PF-06649298
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GC65940
Zandatrigine
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GC65593
6-Benzoylheteratisine
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GC65531
Hardwickiic acid
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GC65416
Flecainide
Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.
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GC65320
Nav1.7-IN-3
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GC65272
APETx2 TFA
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GC65231
N-Bromoacetamide
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GC65150
Flecainide hydrochloride
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GC64691
RY796
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GC64658
Bliretrigine
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GC64206
GDC-0310
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GC64113
Lamotrigine-13C3,d3
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GC64072
NBI-921352
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GC63821
S-Bioallethrin
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GC63799
AZ194
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GC63295
Ranolazine-d8
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GC63261
XPC-6444
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GC63259
VX-150
VX-150 (EOS-62073) is an orally bioavailable pro-drug that rapidly converts into its active moiety, which is a highly selective inhibitor of NaV1.8 relative to the other sodium channel subtypes (>400-fold).
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GC63234
TPC2-A1-P
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GC63108
NHE3-IN-2
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GC63063
Mebeverine hydrochloride
Mebeverine (Duspatalin, Duspatal, Colofac), a 3-phenylethylamine derivative of methoxybenzamine, acts as a musculotropic antispasmodic agent.
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GC62739
(R)-Funapide
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GC61594
Lu AE98134
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GC50707
GX 201
GX 201 是一种选择性 NaV1.7 抑制剂,对 hNaV1.7 的 IC50 \u003c3.2 nM。
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GC47155
Cyfluthrin
A pyrethroid insecticide
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GC61250
Ropivacaine
Ropivacaine is a member of the amino amide class of local anesthetics.
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GC61175
PF-06305591 dihydrate
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GC61110
Nav1.1 activator 1
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GC61046
Methocarbamol D5
An internal standard for the quantification of methocarbamol
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GC60642
Bifenthrin
A synthetic pyrethroid insecticide
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GC39843
Ropivacaine mesylate
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GC39792
Halazone
Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water.
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GC39719
Nigericin
A potassium ionophore
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GC39618
Mexiletine D6 hydrochloride
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GC50299
OD1
Potent hNav1.4, rNav1.6 and rNav1.7 channel activator
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GC50264
ProTx III
Potent Nav1.7 blocker; analgesic
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GC50198
Topiramate - d12
An internal standard for the quantification of topiramate
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GC50174
QAQ dichloride
QAQ dichloride 是一种可光开关的电压门控 Nav 和 Kv 通道阻断剂,可阻断其反式(偶氮苯光电开关)的通道,但不阻断其顺式形式。
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GC50071
NAV 26
NAV 26 (compound 26) 是一种选择性电压门控钠通道 Nav1.7 阻滞剂,IC50 为 0.37 μM。
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GC45985
(±)-Indoxacarb
A broad-spectrum insecticide
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GC38872
Zoniporide hydrochloride hydrate
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GC38865
Tocainide hydrochloride
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GC38484
Dimethyl lithospermate B