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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Sodium Channel(钠离子通道)

Sodium channel are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell plasma membrane.

Products for  Sodium Channel

  1. Cat.No. 产品名称 Information
  2. GC44841 Riluzole (hydrochloride)

    PK 26124 hydrochloride

     An inhibitor of glutamatergic transmission
  3. GC43478 Disopyramide

    达舒平,Dicorantil; SC-7031

     A class Ia antiarrhythmic agent and sodium channel blocker
  4. GC42976 Brevetoxin B

    短裸甲藻毒素2,Brevetoxin-2; PbTx-2

    A neurotoxin
  5. GC42327 4,9-Anhydrotetrodotoxin

    4,9-anhydro-TTX

     A selective blocker of Nav1.6 channels
  6. GC41540 Mepivacaine

    2-甲基-2,6-壬二烯-1-胺

     An Analytical Reference Standard
  7. GC34665 Metaflumizone

    氰氟虫腙; BAS-320I

     Metaflumizone是一种缩氨基脲杀虫剂，为有效的钠离子通道(sodiumchannel)阻滞剂。
  8. GC34492 BI-9627 An NHE1 inhibitor
  9. GC34486 BI 01383298 An NaCT inhibitor
  10. GC33895 FR183998 free base

    FR183998freebase是一种有效的Na+/H+-exchange抑制剂，通过测量在大鼠淋巴细胞、血小板及人血小板pHi值的变化中，得到IC50值分别为0.3nM，6.5nM和3.1nM。
  11. GC33831 Lidocaine hydrochloride (Lignocaine hydrochloride)

    盐酸利多卡因; Lignocaine hydrochloride

     An Analytical Reference Standard
  12. GC33729 Proparacaine Hydrochloride (Proxymetacaine Hydrochloride) Proparacaine盐酸盐是电压门控钠离子通道拮抗剂，ED50为3.4mM。
  13. GC32501 YM758 YM758是一个特异性的窦房结If电流抑制剂。
  14. GC31449 Rimeporide hydrochloride (EMD-87580 hydrochloride)

    EMD-87580 hydrochloride

     Rimeporide hydrochloride (EMD-87580 hydrochloride) (EMD-87580 hydrochloride) 是 Na+/H+ 交换剂 (NHE-1) 的有效选择性抑制剂。
  15. GC31431 Amiloride (MK-870)

    阿米洛利; MK-870

     Amiloride (MK-870)是一种选择性T型钙通道阻滞剂、上皮钠通道(ENaC)和尿激酶型纤溶酶原激活物受体(uTPA)抑制剂,Ki =7 µM。
  16. GC31387 Rimeporide (EMD-87580)

    EMD-87580

     Rimeporide(EMD-87580) is a sodium hydrogen exchanger (NHE-1) inhibitor indicated for patients with Duchenne muscular dystrophy.
  17. GC31302 NHE3-IN-1 NHE3-IN-1是钠/质子交换类型3(sodium/protonexchangertype3(NHE-3))的抑制剂，来自专利WO2011019784A1。
  18. GC31279 Sodium ionophore III (ETH2120)

    钠离子载体，III,ETH2120

     钠离子载体 III (ETH2120) 是一种 Na+ 离子载体。
  19. GC31216 Nicainoprol (RU-42924)

    尼卡普醇,RU-42924

     Nicainoprol (RU-42924) 是一种快速钠通道阻断药，是一种有效的抗心律失常药物。
  20. GC31206 PF 04531083

    N-(6-氨基-5-(2-氯-5-甲氧苯基)吡啶-2-基)-1-甲基-1H-吡唑-5-甲酰胺

     PF04531083是一种选择性的NaV1.8阻滞剂，能够用于神经性或炎症性疼痛的研究。
  21. GC31200 Myomodulin

    肌调蛋白

    Myomodulin是存在于软体动物，昆虫和腹足动物中的神经多肽。
  22. GC31167 Sodium Channel inhibitor 2

    SodiumChannelinhibitor2是一个钠通道阻断剂，来自专利WO2004011439A2，化合物3c。
  23. GC31095 PF-06305591 PF-06305591是一种有效的、高选择性的电压门控钠通道NaV1.8的阻断剂，其IC50值为15nM。具有良好的临床前体外ADME(吸收、分布、代谢和排泄)和安全性。
  24. GC31065 GNE-131 GNE-131是人类钠离子通道NaV1.7(hNaV1.7)有效的、选择性抑制剂，其IC50值为3nM。
  25. GC31002 Nav1.7-IN-2 Nav1.7-IN-2是电压门控钠通道抑制剂,尤其是Nav1.7,IC50值为80nM。
  26. GC30984 XEN907 XEN907是一种新型的螺羟吲哚类NaV1.7阻断剂,抑制hNaV1.7,IC50为3nM。
  27. GC30957 Propoxycaine hydrochloride

    盐酸丙氧卡因；丙氧卡因盐酸盐

    Propoxycaine盐酸盐是一种局部麻醉剂,结合并抑制电压门控钠通道,抑制脉冲起始和传导所需的离子通量,从而导致感觉的丢失。
  28. GC30933 (+)-Kavain

    醉椒素

     A kavalactone with diverse biological activities
  29. GC30917 AM-2099 AM-2099是电压门控钠通道Nav1.7的有效，选择性的抑制剂，对人类Nav1.7的IC50值为0.16μM。
  30. GC30813 Raxatrigine hydrochloride (GSK-1014802 hydrochloride)

    GSK-1014802 hydrochloride; CNV1014802 hydrochloride

     An inhibitor of voltage-gated sodium channels
  31. GC30628 Funapide (TV 45070)

    TV 45070; XEN402

     Funapide (TV 45070) (TV 45070; XEN402) 是一种有效的钠通道 Nav1.7 抑制剂。
  32. GC30415 Propafenone D7 hydrochloride (SA-79 (D7 hydrochloride))

    盐酸普罗帕酮 D7; SA-79 D7 hydrochloride

     Propafenone D7 (SA-79 D7) hydrochloride 是氘标记的 Propafenone，是一种经典的抗心律失常药物。
  33. GC30322 PF-05241328 PF-05241328是有效的、人电压依赖性钠通道(Nav1.7)的选择性抑制剂，其IC50值为31nM。
  34. GC30280 Chlorpromazine D6 hydrochloride

    盐酸氯丙嗪 D6

     An internal standard for the quantification of chlorpromazine
  35. GC30063 Eleclazine hydrochloride (GS 6615 hydrochloride)

    GS 6615 hydrochloride

     An inhibitor of the cardiac late INa
  36. GC19352 Tenapanor

    AZD1722; RDX5791

     A NHE-3 inhibitor
  37. GC19289 PF-06869206 An NaPi2a inhibitor
  38. GC19281 PF-01247324

    2-吡啶甲酰胺,6-氨基-N-甲基-5-(2,3,5-三氯苯基)-

     An inhibitor of Nav1.8 channels
  39. GC18947 PF-05089771 (tosylate) An Nav1.7 channel blocker
  40. GC18203 Annonacin A mitochondrial complex I inhibitor
  41. GC12439 Quinacrine (hydrochloride hydrate)

    Atebrine,Mepacrine

     An acridine compound with diverse biological activities and cell labeling properties
  42. GC15824 Ethyl 3-Aminobenzoate (methanesulfonate)

    3-氨基苯甲酸乙酯甲基磺酸盐,Ethyl m-Aminobenzoate, NSC 93790, Tricaine methanesulfonate , MS-222

     A fish anesthetic
  43. GC13781 QX-314 A selective sodium channel blocker
  44. GC10234 GSK1014802(CNV1014802)

    GSK-1014802; CNV1014802

     GSK1014802(CNV1014802) (GSK-1014802)是一种新型的小分子状态依赖性钠通道阻滞剂； Nav1.7 钠通道抑制剂。
  45. GC17842 CARIPORIDE

    卡立泊来德; HOE-642

     An NHE-1 inhibitor
  46. GC12413 Rostafuroxin (PST 2238)

    PST 2238

     An endogenous ouabain blocker at the Na+/K+ ATPase
  47. GC10830 GS967 A selective inhibitor of cardiac late sodium current
  48. GC12805 Procainamide HCl

    盐酸普鲁卡因胺

     An Analytical Reference Standard
  49. GC17395 ICA 121431 A selective Nav1.1 and Nav1.3 channel blocker
  50. GC12109 PF 04885614 PF 04885614 是一种有效的 NaV1.8 抑制剂，提取自专利 US2018328915。
  51. GC12676 TC-N 1752

    TC-N 1752, Voltage-gated Sodium Channel 1.7

     An inhibitor of Nav1.7 channels

Items 101 to 150 of 204 total

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