Autophagy(自噬)
Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.
- Cat.No. 产品名称 Information
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GC25651
MRT68921 HCl
MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
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GC25650
MRT67307 HCl
MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy.
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GC52477
Corynoxine (hydrochloride)
An indole alkaloid
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GC52467
Cell Death Screening Library
For screening a variety of cell death pathways
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GC65575
Cabazitaxel-d6
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GC65540
eIF4A3-IN-2
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GC65432
LV-320
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GC65386
Trimetazidine-d8 dihydrochloride
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GC65331
IZCZ-3
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GC65318
BOLD-100
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GC65307
S130
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GC65297
MW-150
An inhibitor of p38α MAPK
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GC65191
DC-LC3in-D5
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GC65115
mTOR inhibitor-1
mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy.
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GC65106
Pregnenolone-d4-1
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GC65072
Niacin-13C6
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GC65010
Bortezomib-d8
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GC65004
Apostatin-1
Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). Apostatin-1 inhibits bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.
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GC64524
Clematichinenoside AR
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GC52057
QN523
An anticancer agent
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GC49815
Oleuropein aglycone
A polyphenol with diverse biological activities
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GC64378
Valproic acid-d6
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GC64363
Lumefantrine-d9
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GC64358
Olacaftor
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GC64325
Ligustilide
Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. Solutions are best fresh-prepared.
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GC64223
Sophocarpine monohydrate
An alkaloid with diverse biological activities
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GC64136
Desmethyl Naproxen-d3
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GC64113
Lamotrigine-13C3,d3
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GC64098
Isoniazid-d4
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GC64076
Nortriptyline
Nortriptyline hydrochloride (Desitriptyline, ELF-101, EN-7048, Desmethylamitriptyline) is the hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression.
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GC64070
Omeprazole-d3-1
An internal standard for the quantification of omeprazole
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GC64032
Salicylic acid-d6
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GC64013
ZX-29
ZX-29 is a potent and selective ALK inhibitor with an IC50s of 2.1, 1.3 and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively.
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GC64003
Carvedilol-d4
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GC63840
Tat-beclin 1
Tat-beclin 1 (Tat-BECN1), a peptide known to stimulate autophagy through mobilization of endogenous Beclin 1, induces autophagy in vitro and in vivo and improves clinical outcomes.
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GC63827
Atropine sulfate monohydrate
A non-
selective muscarinic acetylcholine receptor antagonist -
GC49670
Indium (III) thiosemicarbazone 5b
An anticancer agent
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GC63601
Trimetazidine
An Analytical Reference Standard
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GC63515
Hoechst 33342
A fluorescent DNA probe
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GC63316
Ammonium chloride
Ammonium chloride is an inorganic compound and can be used for establishing the rat model of renal calcium oxalate calculus, it is also an autophagy inhibitor.
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GC62881
CA77.1
CA77.1 (CA) is a potent, brain-penetrant and orally active activator of chaperone-mediated autophagy (CMA) for the treament of Alzheimer's disease (AD).
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GC62853
Aumitin
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GC49341
Spermidine-d6
An internal standard for the quantification of spermidine
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GC49308
Ungeremine
A betaine-type alkaloid with diverse biological activities
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GC49189
(E/Z)-4-hydroxy Tamoxifen-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
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GC49084
PHY34
An inhibitor of late-stage autophagy
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GC49016
Dimethyl 2-ketoglutarate
An esterified form of α-ketoglutarate
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GC62630
TAS-117 hydrochloride
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GC62626
ICCB-19 hydrochloride
ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy.
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GC62564
Mito-LND