Home >> Signaling Pathways >> Ubiquitination/ Proteasome >> Autophagy


Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

  1. Cat.No. 产品名称 Information
  2. GC25651 MRT68921 HCl MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
  3. GC25650 MRT67307 HCl MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy.
  4. GC52477 Corynoxine (hydrochloride) An indole alkaloid
  5. GC52467 Cell Death Screening Library For screening a variety of cell death pathways
  6. GC65575 Cabazitaxel-d6
  7. GC65540 eIF4A3-IN-2
  8. GC65432 LV-320
  9. GC65386 Trimetazidine-d8 dihydrochloride
  10. GC65331 IZCZ-3
  11. GC65318 BOLD-100
  12. GC65307 S130
  13. GC65297 MW-150 An inhibitor of p38α MAPK
  14. GC65191 DC-LC3in-D5
  15. GC65115 mTOR inhibitor-1 mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy.
  16. GC65106 Pregnenolone-d4-1
  17. GC65072 Niacin-13C6
  18. GC65010 Bortezomib-d8
  19. GC65004 Apostatin-1 Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N). Apostatin-1 inhibits bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.
  20. GC64524 Clematichinenoside AR
  21. GC52057 QN523 An anticancer agent
  22. GC49815 Oleuropein aglycone A polyphenol with diverse biological activities
  23. GC64378 Valproic acid-d6
  24. GC64363 Lumefantrine-d9
  25. GC64358 Olacaftor
  26. GC64325 Ligustilide Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. Solutions are best fresh-prepared.
  27. GC64223 Sophocarpine monohydrate An alkaloid with diverse biological activities
  28. GC64136 Desmethyl Naproxen-d3
  29. GC64113 Lamotrigine-13C3,d3
  30. GC64098 Isoniazid-d4
  31. GC64076 Nortriptyline Nortriptyline hydrochloride (Desitriptyline, ELF-101, EN-7048, Desmethylamitriptyline) is the hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression.
  32. GC64070 Omeprazole-d3-1 An internal standard for the quantification of omeprazole
  33. GC64032 Salicylic acid-d6
  34. GC64013 ZX-29 ZX-29 is a potent and selective ALK inhibitor with an IC50s of 2.1, 1.3 and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively.
  35. GC64003 Carvedilol-d4
  36. GC63840 Tat-beclin 1 Tat-beclin 1 (Tat-BECN1), a peptide known to stimulate autophagy through mobilization of endogenous Beclin 1, induces autophagy in vitro and in vivo and improves clinical outcomes.
  37. GC63827 Atropine sulfate monohydrate A non-selective muscarinic acetylcholine receptor antagonist
  38. GC49670 Indium (III) thiosemicarbazone 5b An anticancer agent
  39. GC63601 Trimetazidine An Analytical Reference Standard
  40. GC63515 Hoechst 33342 A fluorescent DNA probe
  41. GC63316 Ammonium chloride Ammonium chloride is an inorganic compound and can be used for establishing the rat model of renal calcium oxalate calculus, it is also an autophagy inhibitor.
  42. GC62881 CA77.1 CA77.1 (CA) is a potent, brain-penetrant and orally active activator of chaperone-mediated autophagy (CMA) for the treament of Alzheimer's disease (AD).
  43. GC62853 Aumitin
  44. GC49341 Spermidine-d6 An internal standard for the quantification of spermidine
  45. GC49308 Ungeremine A betaine-type alkaloid with diverse biological activities
  46. GC49189 (E/Z)-4-hydroxy Tamoxifen-d5 An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
  47. GC49084 PHY34 An inhibitor of late-stage autophagy
  48. GC49016 Dimethyl 2-ketoglutarate An esterified form of α-ketoglutarate
  49. GC62630 TAS-117 hydrochloride
  50. GC62626 ICCB-19 hydrochloride ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy.
  51. GC62564 Mito-LND

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