E3 Ligase(E3 连接酶)
E3 ligases perform the last step in the ubiquitination cascade. They transfer the ubiquitin from the active site cysteine of E2 enzyme to the substrate lysine or N terminus. The loss of function or mis-targeting of the E3 ligases are associated with various cancer types.
Products for E3 Ligase
- Cat.No. 产品名称 Information
-
GC25019
5-amino-2,4-dimethylpyridine (5A-DMP)
5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts
-
GC50234
N106
N-(4-甲氧基苯并[D]噻唑-2-基)-5-(4-甲氧基苯基)-1,3,4-噁二唑-2-胺
An activator of SERCA2A sumoylation -
GC44291
NAB 2
An inhibitor of α-synuclein-induced toxicity
-
GC10940
PRT 4165
NSC600157
An inhibitor of PRC1 ubiquitin ligases -
GC15492
SMER 3
SCFMET30 Inhibitor, MET30 Antagonist
A selective inhibitor of SCFMET30 ubiquitin E3 ligase -
GC11869
SZL P1-41
SZL P1-41是一种特异性S期激酶相关蛋白2(Skp2)抑制剂。
-
GC15017
NSC 624206
An inhibitor of ubiquitin-activating enzyme (E1)