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Home >> Signaling Pathways >> Tyrosine Kinase >> LRRK2

LRRK2(富亮氨酸重复激酶2)

LRRK2 (Leucine-rich repeat kinase 2) is an enzyme that interacts with parkin and is associated with Parkinson's disease and also Crohn's disease.

  1. Cat.No. 产品名称 Information
  2. GC65390 LRRK2 inhibitor 1
  3. GC64730 EB-42486
  4. GC64566 PF-06454589
  5. GC64506 PF-06456384 trihydrochloride
  6. GC36888 PFE-360 PFE-360(PF-06685360) is a brain-penetrant and selective LRRK2 small-molecule kinase inhibitors.
  7. GC36171 GNE-7915 tosylate A selective LRRK2 inhibitor
  8. GC35792 CZC-25146 hydrochloride A potent LRRK2 inhibitor
  9. GC30769 MLi-2 An LRRK2 inhibitor
  10. GC19205 JH-II-127 An inhibitor of wild-type and mutant forms of LRRK2
  11. GC12370 IKK-16 (hydrochloride) A potent inhibitor of IKKs
  12. GC13850 PF-06447475 PF-06447475 是一种高效、选择性和脑渗透性 LRRK2 抑制剂，IC50 为 3 nM。
  13. GC13868 GNE-9605 A potent LRRK2 inhibitor
  14. GC18049 GSK2578215A A potent LRRK2 inhibitor
  15. GC16731 CZC 54252 hydrochloride An LRRK2 inhibitor
  16. GC16038 CZC-25146 A potent LRRK2 inhibitor
  17. GC15196 GNE0877 A selective LRRK2 inhibitor
  18. GC12121 GNE-7915 A selective LRRK2 inhibitor
  19. GC12180 IKK-16 (IKK Inhibitor VII) IKK-16 (IKK Inhibitor VII) 是一种选择性 IκB 激酶 (IKK) 抑制剂，作用于 IKK2、IKK 复合物和 IKK1，IC50 分别为 40 nM、70 nM 和 200 nM。
  20. GC13098 HG-10-102-01 A brain penetrant inhibitor of wild-type and G2019S mutant LRRK2
  21. GC10809 LRRK2-IN-1 A selective LRRK2 inhibitor

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