Pyk2(富含脯氨酸的酪氨酸激酶2)

Pyk2 is a nonreceptor cytoplasmic protein tyrosine kinase. It is involved in Ca(2+)-induced regulation of ion channel and MAP kinase activation. It plays a role in various cellular events such as cell motility, cell polarization, adhesion, reorganization of actin cytoskeleton etc.

Cat.No. 产品名称 Information
GC61852 PF-4618433 PF-4618433 是一种有效的、选择性的 PYK2 抑制剂，IC50 值为 637 nM。PF-4618433 可能适用于研究骨质疏松症，颅面和阑尾骨骼缺损以及靶向骨再生。
GC14407 PF-431396 A FAK/PYK2 dual inhibitor
GC16821 TAE226(NVP-TAE226) A dual inhibitor of FAK and IGF-1R
GC10810 PF-562271 HCl PF-562271 (VS-6062) hydrochloride 是一种有效的 ATP 竞争性和可逆的 FAK 和 Pyk2 激酶抑制剂，IC50 分别为 1.5 nM 和 13 nM。
GC14767 PF-00562271 A selective FAK/PYK2 inhibitor
GC15380 PF-562271 A selective FAK/PYK2 inhibitor