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FAK (focal adhesion kinase), also known as PTK2, is a focal adhesion-associated protein kinase involved in cellular adhesion and spreading processes.

  1. Cat.No. 产品名称 Information
  2. GC68463 ULK1-IN-2
  3. GC68030 FAK-IN-7
  4. GC65886 BI-853520
  5. GC65457 BI-3663
  6. GC64992 YH-306
  7. GC64888 GSK215 GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader, which exerts FAK degradation in A549 non-small-cell lung cancer cells with DC50 of 1.3 nM by a strong time-dependence way and maximal degradation (Dmax) near the limit of the assay quantification (Dmax 99%).
  8. GC64377 Batatasin III
  9. GC64015 AMP-945 AMP-945 is an inhibitor of the focal adhesion kinase (FAK).
  10. GC62111 PND-1186 hydrochloride A potent FAK inhibitor
  11. GC38437 Fangchinoline An alkaloid with diverse biological activities
  12. GC36985 PROTAC FAK degrader 1
  13. GC36025 FAK inhibitor 2
  14. GC35827 Defactinib hydrochloride A FAK inhibitor
  15. GC35728 Conteltinib
  16. GC44605 Petunidin (chloride) An O-methylated anthocyanidin
  17. GC34488 BI-4464 BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM.
  18. GC33045 NAMI-A
  19. GC32979 Chloropyramine hydrochloride Chloropyramine hydrochloride (Halopyramine) is a histamine receptor H1 antagonist and has anti-cholinergic, antispasmodic, and antiallergic effects.
  20. GC19179 GSK2256098 A FAK inhibitor
  21. GC17500 SU6656 Inhibitor of Src kinases
  22. GC16813 Defactinib A FAK inhibitor
  23. GC14489 Y 11 An inhibitor of FAK1
  24. GC12174 FAK Inhibitor 14 An inhibitor of the FAK1
  25. GC11107 PF-573228 A selective focal adhesion kinase inhibitor
  26. GC15273 CEP-37440 A dual inhibitor of FAK1 and ALK
  27. GC14407 PF-431396 A FAK/PYK2 dual inhibitor
  28. GC16821 TAE226(NVP-TAE226) A dual inhibitor of FAK and IGF-1R
  29. GC10810 PF-562271 HCl PF-562271 (VS-6062) hydrochloride 是一种有效的 ATP 竞争性和可逆的 FAK 和 Pyk2 激酶抑制剂,IC50 分别为 1.5 nM 和 13 nM。
  30. GC14767 PF-00562271 A selective FAK/PYK2 inhibitor
  31. GC15380 PF-562271 A selective FAK/PYK2 inhibitor
  32. GC13410 Masitinib (AB1010) An inhibitor of c-Kit
  33. GC15164 PND-1186 A potent FAK inhibitor

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