FLT3(FMS样酪氨酸激酶3)
FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.
- Cat.No. 产品名称 Information
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GC26021
UNC2025 HCl
UNC2025 HCl is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.
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GC66451
AKN-028 acetate
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GC65984
FLT3-IN-16
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GC65555
PROTAC FLT-3 degrader 1
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GC65179
MAX-40279
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GC64583
MAX-40279 hemiadipate
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GC64582
MAX-40279 hemifumarate
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GC63936
FLT3-IN-10
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GC63864
(E/Z)-Zotiraciclib hydrochloride
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GC63805
4SC-203
4SC-203 (SC71710) is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).
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GC63507
HM43239
HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.
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GC62665
JAK2/FLT3-IN-1 TFA
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GC62516
UNC5293
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GC62500
JAK2-IN-7
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GC62499
ATH686
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GC62112
Zotiraciclib
Zotiraciclib (SB1317; TG02) is a novel small molecule potent CDK/JAK2/FLT3 inhibitor, emerged with potent CDK (IC50 against CDKs 1, 2 and 9 = 9, 5 and 3 nM, respectively), FLT3 (IC50 = 19 nM) and JAK2 (IC50 = 19 nM) potency.
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GC39689
3-Hydroxy Midostaurin
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GC38853
Tandutinib hydrochloride
An antagonist of PDGFRβ, FLT3, and c-
Kit -
GC38412
Crotonoside
A guanosine analog with diverse biological activities
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GC37857
UNC2025 hydrochloride
An orally bioavailable inhibitor of Mer and Flt3
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GC37723
TAK-659
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
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GC37665
Sorafenib (D4)
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GC37664
Sorafenib (D3)
An internal standard for the quantification of sorafenib
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GC37538
Ripretinib
A KIT and PDGFRα inhibitor
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GC36585
Merestinib dihydrochloride
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GC36135
Gilteritinib hemifumarate
A FLT3 inhibitor
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GC36056
FLT3-IN-6
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GC36055
FLT3-IN-4
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GC35651
Cenisertib
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GC35545
BPR1K871
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GC35544
BPR1J-097 Hydrochloride
An FLT3 inhibitor
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GC35315
AMG 925 HCl
A dual inhibitor of FLT3 and Cdk4
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GC43885
Hypothemycin
A resorcylic acid lactone polyketide with diverse biological activities
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GC33362
Amuvatinib hydrochloride (MP470 hydrochloride)
A multi-targeted RTK inhibitor
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GC33242
FLT3-IN-1 Succinate
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GC33141
SKLB4771 (FLT3-IN-1)
SKLB4771 is a potent and selective inhibitor of human receptor-type tyrosine-protein kinase FLT3 with IC50 of 10?nM.
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GC33064
CG-806 (Luxeptinib)
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GC33049
FN-1501
FN-1501 is a potent inhibitor of Fms-like receptor tyrosine kinase 3 (FLT3) and cyclin-dependent kinase (CDK), with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively.
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GC32995
JNJ-47117096 hydrochloride (MELK-T1 hydrochloride)
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GC32968
FLT3-IN-1
FF-10101 is a novel irreversible FLT3 inhibitor with ic50 of 0.20 nM and 0.16 nM for FLT3 (WT) and FLT3(D835Y), respectively.
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GC32769
MRX-2843 (UNC2371)
A Mer and FLT3 inhibitor
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GC19772
FLT3-IN-3
An FLT3 inhibitor
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GC19482
Gilteritinib
A FLT3 inhibitor
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GC19332
Sitravatinib
A multi-kinase inhibitor
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GC19158
FLT3-IN-2
An inhibitor of FLT3, c-Kit, and c-FMS
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GC19092
CCT241736
A dual inhibitor of Aurora kinases and FLT3
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GC19080
BPR1J-097
An FLT3 inhibitor
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GC18167
AC710
A PDGFR family kinase inhibitor
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GC12251
Tandutinib (MLN518) HCl
FLT3 inhibitor,potent and selective
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GC14582
SU5614
A multi-kinase inhibitor