FLT3(FMS样酪氨酸激酶3)

Cat.No. 产品名称 Information

GC26021 UNC2025 HCl UNC2025 HCl is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

GC66451 AKN-028 acetate

GC65984 FLT3-IN-16

GC65555 PROTAC FLT-3 degrader 1

GC65179 MAX-40279

GC64583 MAX-40279 hemiadipate

GC64582 MAX-40279 hemifumarate

GC63936 FLT3-IN-10

GC63864 (E/Z)-Zotiraciclib hydrochloride

GC63805 4SC-203 4SC-203 (SC71710) is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).

GC63507 HM43239 HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.

GC62665 JAK2/FLT3-IN-1 TFA

GC62516 UNC5293

GC62500 JAK2-IN-7

GC62499 ATH686

GC62112 Zotiraciclib Zotiraciclib (SB1317; TG02) is a novel small molecule potent CDK/JAK2/FLT3 inhibitor, emerged with potent CDK (IC50 against CDKs 1, 2 and 9 = 9, 5 and 3 nM, respectively), FLT3 (IC50 = 19 nM) and JAK2 (IC50 = 19 nM) potency.

GC39689 3-Hydroxy Midostaurin

GC38853 Tandutinib hydrochloride An antagonist of PDGFRβ, FLT3, and c-Kit

GC38412 Crotonoside A guanosine analog with diverse biological activities

GC37857 UNC2025 hydrochloride An orally bioavailable inhibitor of Mer and Flt3

GC37723 TAK-659 TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.

GC37665 Sorafenib (D4)

GC37664 Sorafenib (D3) An internal standard for the quantification of sorafenib

GC37538 Ripretinib A KIT and PDGFRα inhibitor

GC36585 Merestinib dihydrochloride

GC36135 Gilteritinib hemifumarate A FLT3 inhibitor

GC36056 FLT3-IN-6

GC36055 FLT3-IN-4

GC35651 Cenisertib

GC35545 BPR1K871

GC35544 BPR1J-097 Hydrochloride An FLT3 inhibitor

GC35315 AMG 925 HCl A dual inhibitor of FLT3 and Cdk4

GC43885 Hypothemycin A resorcylic acid lactone polyketide with diverse biological activities

GC33362 Amuvatinib hydrochloride (MP470 hydrochloride) A multi-targeted RTK inhibitor

GC33242 FLT3-IN-1 Succinate

GC33141 SKLB4771 (FLT3-IN-1) SKLB4771 is a potent and selective inhibitor of human receptor-type tyrosine-protein kinase FLT3 with IC50 of 10?nM.

GC33064 CG-806 (Luxeptinib)

GC33049 FN-1501 FN-1501 is a potent inhibitor of Fms-like receptor tyrosine kinase 3 (FLT3) and cyclin-dependent kinase (CDK), with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively.