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FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.

  1. Cat.No. 产品名称 Information
  2. GC26021 UNC2025 HCl UNC2025 HCl is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.
  3. GC66451 AKN-028 acetate
  4. GC65984 FLT3-IN-16
  5. GC65555 PROTAC FLT-3 degrader 1
  6. GC65179 MAX-40279
  7. GC64583 MAX-40279 hemiadipate
  8. GC64582 MAX-40279 hemifumarate
  9. GC63936 FLT3-IN-10
  10. GC63864 (E/Z)-Zotiraciclib hydrochloride
  11. GC63805 4SC-203 4SC-203 (SC71710) is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).
  12. GC63507 HM43239 HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.
  13. GC62665 JAK2/FLT3-IN-1 TFA
  14. GC62516 UNC5293
  15. GC62500 JAK2-IN-7
  16. GC62499 ATH686
  17. GC62112 Zotiraciclib Zotiraciclib (SB1317; TG02) is a novel small molecule potent CDK/JAK2/FLT3 inhibitor, emerged with potent CDK (IC50 against CDKs 1, 2 and 9 = 9, 5 and 3 nM, respectively), FLT3 (IC50 = 19 nM) and JAK2 (IC50 = 19 nM) potency.
  18. GC39689 3-Hydroxy Midostaurin
  19. GC38853 Tandutinib hydrochloride An antagonist of PDGFRβ, FLT3, and c-Kit
  20. GC38412 Crotonoside A guanosine analog with diverse biological activities
  21. GC37857 UNC2025 hydrochloride An orally bioavailable inhibitor of Mer and Flt3
  22. GC37723 TAK-659 TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
  23. GC37665 Sorafenib (D4)
  24. GC37664 Sorafenib (D3) An internal standard for the quantification of sorafenib
  25. GC37538 Ripretinib A KIT and PDGFRα inhibitor
  26. GC36585 Merestinib dihydrochloride
  27. GC36135 Gilteritinib hemifumarate A FLT3 inhibitor
  28. GC36056 FLT3-IN-6
  29. GC36055 FLT3-IN-4
  30. GC35651 Cenisertib
  31. GC35545 BPR1K871
  32. GC35544 BPR1J-097 Hydrochloride An FLT3 inhibitor
  33. GC35315 AMG 925 HCl A dual inhibitor of FLT3 and Cdk4
  34. GC43885 Hypothemycin A resorcylic acid lactone polyketide with diverse biological activities
  35. GC33362 Amuvatinib hydrochloride (MP470 hydrochloride) A multi-targeted RTK inhibitor
  36. GC33242 FLT3-IN-1 Succinate
  37. GC33141 SKLB4771 (FLT3-IN-1) SKLB4771 is a potent and selective inhibitor of human receptor-type tyrosine-protein kinase FLT3 with IC50 of 10?nM.
  38. GC33064 CG-806 (Luxeptinib)
  39. GC33049 FN-1501 FN-1501 is a potent inhibitor of Fms-like receptor tyrosine kinase 3 (FLT3) and cyclin-dependent kinase (CDK), with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively.
  40. GC32995 JNJ-47117096 hydrochloride (MELK-T1 hydrochloride)
  41. GC32968 FLT3-IN-1 FF-10101 is a novel irreversible FLT3 inhibitor with ic50 of 0.20 nM and 0.16 nM for FLT3 (WT) and FLT3(D835Y), respectively.
  42. GC32769 MRX-2843 (UNC2371) A Mer and FLT3 inhibitor
  43. GC19772 FLT3-IN-3 An FLT3 inhibitor
  44. GC19482 Gilteritinib A FLT3 inhibitor
  45. GC19332 Sitravatinib A multi-kinase inhibitor
  46. GC19158 FLT3-IN-2 An inhibitor of FLT3, c-Kit, and c-FMS
  47. GC19092 CCT241736 A dual inhibitor of Aurora kinases and FLT3
  48. GC19080 BPR1J-097 An FLT3 inhibitor
  49. GC18167 AC710 A PDGFR family kinase inhibitor
  50. GC12251 Tandutinib (MLN518) HCl FLT3 inhibitor,potent and selective
  51. GC14582 SU5614 A multi-kinase inhibitor

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