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Home >> Signaling Pathways >> Tyrosine Kinase >> FLT3

FLT3(FMS样酪氨酸激酶3)

FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.

Products for  FLT3

  1. Cat.No. 产品名称 Information
  2. GC14582 SU5614 A multi-kinase inhibitor
  3. GC17959 AZD2932 A multi-kinase inhibitor
  4. GC16604 Altiratinib A multiple kinase inhibitor
  5. GC15556 UNC2025 An orally bioavailable inhibitor of Mer and Flt3
  6. GC12178 G-749 An FLT3 kinase inhibitor
  7. GC11205 5'-Fluoroindirubinoxime An inhibitor of FLT3 kinase
  8. GC14007 DCC-2036 (Rebastinib) An orally bioavailable tyrosine kinase inhibitor
  9. GC15254 Tandutinib (MLN518) An antagonist of PDGFRβ, FLT3, and c-Kit
  10. GC14974 AMG 925 A dual inhibitor of FLT3 and Cdk4
  11. GC15739 CHIR-124 A selective Chk1 inhibitor
  12. GC14906 Crenolanib (CP-868596) An inhibitor of PDGFRα/β and FLT3
  13. GC12058 TCS 359 A cell-permeable FLT3 inhibitor
  14. GC17615 Quizartinib (AC220) An inhibitor of FLT3
  15. GC14396 Ponatinib (AP24534) An inhibitor of native and mutant Bcr-Abl
  16. GC15779 Cabozantinib (XL184, BMS-907351) A VEGFR2 inhibitor
  17. GC13547 Dovitinib (TKI-258, CHIR-258) A multi-kinase inhibitor
  18. GC17958 Linifanib (ABT-869) A dual VEGFR and PDGFR family kinase inhibitor
  19. GC16499 Sorafenib Tosylate A multi-kinase inhibitor
  20. GC17033 Lestaurtinib A potent JAK2 and PRK1 kinase inhibitor
  21. GC15307 SU5416

    A tyrosine kinase inhibitor
  22. GC11455 Silvestrol Silvestrol 是一种真核翻译起始因子 4A (eIF4A) 抑制剂，从 Agave americana Linn 中分离出来。Silvestrol 诱导自噬和半胱天冬酶介导的细胞凋亡。
  23. GC12064 SB1317 A multi-kinase inhibitor
  24. GC11057 LY2801653 A MET kinase inhibitor
  25. GC10914 AST 487 A multi-kinase inhibitor
  26. GC16391 Amuvatinib (MP-470, HPK 56) A multi-targeted RTK inhibitor
  27. GC14592 KW 2449 A multi-kinase inhibitor
  28. GC10638 AT9283 A broad spectrum kinase inhibitor
  29. GC16519 ENMD-2076 A multi-kinase inhibitor
  30. GC12145 ENMD-2076 L-(+)-Tartaric acid ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
  31. GC13848 LY2784544 Potent inhibitor of JAK2
  32. GC10035 TG101209 An inhibitor of JAK2, FLT3, RET, and JAK3
  33. GC17369 Sorafenib

    Sorafenib acts as a multi-kinase inhibitor, targeting Raf-1 and B-Raf with IC50 values of 6 nM and 22 nM, respectively.

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