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IGF1R(胰岛素样生长因子1受体)

IGF1R (insulin-Like growth factor 1 receptor) is a receptor tyrosine kinase that bind to insulin-like growth factor 1 with high affinity. It plays a vital role in in cell growth, cell survival and malignant transformation etc.

  1. Cat.No. 产品名称 Information
  2. GC25881 S961 S961 is a biosynthetic insulin receptor antagonist that inhibits cellular proliferation and colony formation in breast tumour cells.
  3. GC63297 I-OMe-Tyrphostin AG 538
  4. GC61111 NBI-31772 hydrate A nonpeptide ligand that releases IGF-1 from IGFBP
  5. GC45789 Ceritinib-d7 An internal standard for the quantification of ceritinib
  6. GC36311 Indirubin Derivative E804
  7. GC34414 AZ7550 Mesylate (AZ7550 trimesylate salt) An active metabolite of AZ 9291
  8. GC34287 AZ7550 hydrochloride An active metabolite of AZ 9291
  9. GC33072 AZ7550 An active metabolite of AZ 9291
  10. GC31706 Ginsenoside Rg5 A ginsenoside with diverse biological activities
  11. GC12712 NT157 IRS-1/2 抑制剂,抑制 IGF-1R 和 STAT3 信号通路
  12. GC14310 NVP-ADW742 An IGF-1R inhibitor
  13. GC14189 AZD-3463 An ALK and IGF-1R inhibitor
  14. GC16821 TAE226(NVP-TAE226) A dual inhibitor of FAK and IGF-1R
  15. GC12273 GSK1838705A An IGF-1R and IR inhibitor
  16. GC15749 Linsitinib Dual inhibitor of IGF-1R and InsR tyrosine kinases
  17. GC14552 LDK378 An ALK inhibitor
  18. GC16991 PQ 401 An inhibitor of IGF-1R
  19. GC12963 NVP-AEW541 An IGF-1R inhibitor
  20. GC17612 GSK1904529A A dual inhibitor of InsR and IGF-1R kinases
  21. GC16712 BMS-754807 Dual inhibitor of IGF-1R and InsR tyrosine kinases
  22. GC13697 AG-1024 A selective inhibitor of IGF-1R
  23. GC17773 BMS-536924 A dual inhibitor of IGF-1R and IR
  24. GC13102 XL228 A tyrosine kinase inhibitor
  25. GC17452 LDK378 dihydrochloride LDK378 dihydrochloride (LDK378 dihydrochloride) 是一种选择性、口服生物利用度和 ATP 竞争性的 ALK 酪氨酸激酶抑制剂,IC50 为 200 pM。
  26. GC17045 AXL1717 A potent and selective inhibitor of IGF-1R

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