FGFR(成纤维细胞生长因子)
FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.
- Cat.No. 产品名称 Information
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GC65516
Bemarituzumab
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GC65515
Aprutumab
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GC65212
FGFR1/DDR2 inhibitor 1
FGFR1/DDR2 inhibitor 1 is an inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoidin domain receptor 2 (DDR2).
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GC65179
MAX-40279
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GC64950
ODM-203
A dual inhibitor of VEGFR and FGFR
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GC64875
Gunagratinib
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GC64475
FGFR2-IN-2
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GC49700
Takeda-6d
A dual inhibitor of RAF kinases and VEGFR2
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GC49686
N-desmethyl Regorafenib N-oxide
An active metabolite of regorafenib
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GC63395
FGFR-IN-1
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GC62696
E7090 succinate
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GC62675
SM1-71
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GC62602
FGFR4-IN-5
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GC62291
(Z)-Orantinib
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GC62274
CPL304110
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GC61957
SU4984
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GC60726
CP-547632 TFA
A potent inhibitor of VEGFR2 and bFGF
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GC50051
FIIN 1 hydrochloride
FIIN 1 hydrochloride 是一种有效的、不可逆的、选择性的 FGFR 抑制剂。 FIIN 1 hydrochloride 与 FGFR1/2/3/4 和 Flt1/4 结合,Kd 分别为 2.8/6.9/5.4/120 nM 和 32/120 nM。 FIIN 1 hydrochloride 对 FGFR1/2/3/4 的生化 IC50 分别为 9.2、6.2、11.9 和 189 nM。
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GC45828
Ponatinib-d8
An internal standard for the quantification of ponatinib
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GC38575
CP-547632 hydrochloride
A potent inhibitor of VEGFR2 and bFGF
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GC37773
TG 100801 Hydrochloride
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GC37772
TG 100572 Hydrochloride
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GC37771
TG 100572
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GC37679
SSR128129E free acid
An FGFR inhibitor
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GC36745
Nintedanib esylate
Nintedanib esylate, as a kinase inhibitor, used for the treatment of non-small cell lung cancer suffered from first-pass metabolism which resulted in low oral bioavailability .
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GC36546
Masitinib mesylate
An inhibitor of c-Kit
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GC36438
Lenvatinib mesylate
An inhibitor of VEGFR2 and VEGFR3
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GC36044
FIIN-3
An inhibitor of FGFRs
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GC44583
PD 089828
An inhibitor of EGFR, PDGFβ, FGF, and c-Src
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GC34476
ASP5878
ASP5878 is a novel FGFR-selective inhibitor with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L for recombinant FGFR1, 2, 3, and 4, respectively.
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GC34067
Rogaratinib (BAY1163877)
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GC34026
Tyrosine kinase-IN-1
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GC33519
2,5-Dihydroxybenzoic acid
A benzoic acid with diverse biological activities
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GC33352
CP-547632
A potent inhibitor of VEGFR2 and bFGF
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GC32915
Pemigatinib
An FGFR inhibitor
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GC32835
PP58
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GC32805
Sulfatinib (HMPL-012)
A multi-kinase inhibitor
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GC32802
PRN1371
An irreversible pan-FGFR inhibitor
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GC32760
Dovitinib lactate (CHIR-258 lactate)
A multi-kinase inhibitor
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GC32127
Alofanib (RPT835)
An allosteric inhibitor of FGFR2
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GC31495
PF-05231023
A bioconjugation linker
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GC30767
Heparan Sulfate
硫酸乙酰肝素是一种复杂的线性多糖,作为糖蛋白的一部分存在,称为硫酸乙酰肝素蛋白聚糖,在细胞表面和细胞外基质中大量表达。
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GC19399
Derazantinib
An inhibitor of FGFR
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GC19341
SUN11602
An FGF2 mimetic
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GC19317
S49076
S49076 是一种新型、有效的 MET、AXL/MER 和 FGFR1/2/3 抑制剂,IC50 值低于 20 nM。
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GC19279
PD-166866
A potent inhibitor of FGFR1
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GC19187
H3B-6527
An FGFR4 inhibitor
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GC19156
TAS-120
An orally bioavailable, irreversible inhibitor of FGFRs
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GC19155
FGFR4-IN-1
An inhibitor of FGFR4
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GC19154
Roblitinib
An FGFR4 inhibitor