FGFR(成纤维细胞生长因子)

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

Products for FGFR

Cat.No. 产品名称 Information
GC10055 BGJ398 (Infigratinib)
FGFR抑制剂(NVP-BGJ398),BGJ398,BGJ-398,Infigratinib
BGJ398 (Infigratinib)是一种口服的ATP竞争性泛FGFR酪氨酸激酶抑制剂（FGFR1：IC₅₀ = 0.9nM；FGFR2：IC₅₀ = 1.4nM；FGFR3：IC₅₀ = 1nM；FGFR4：IC₅₀ = 60nM）。
GN10540 Fumalic acid
天然阿魏酸, 来源于川芎, Coniferic acid

A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
GN10527 Formononetin
刺芒柄花素: Biochanin B: Flavosil; Formononetol
Formononetin是一种强效的FGFR2抑制剂，其IC₅₀值约为4.31μM。Formononetin能有效抑制血管生成和肿瘤生长。