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Home >> Signaling Pathways >> Tyrosine Kinase >> FGFR

FGFR(成纤维细胞生长因子)

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

Products for  FGFR

  1. Cat.No. 产品名称 Information
  2. GC19187 H3B-6527 An FGFR4 inhibitor
  3. GC19156 TAS-120 An orally bioavailable, irreversible inhibitor of FGFRs
  4. GC19155 FGFR4-IN-1 An inhibitor of FGFR4
  5. GC19154 Roblitinib An FGFR4 inhibitor
  6. GC19142 Erdafitinib A pan-FGFR inhibitor
  7. GC19075 BLU-554 A potent inhibitor of FGFR4
  8. GC10759 CH5183284 (Debio-1347) An inhibitor of FGFR1, 2, and 3
  9. GC10833 BLU9931 A selective FGFR4 inhibitor
  10. GC15801 ACTB-1003 A multi-kinase inhibitor
  11. GC17323 FIIN-2 An FGFR inhibitor
  12. GC12049 PD 161570 An inhibitor of FGFR1
  13. GC10491 SSR128129E An FGFR inhibitor
  14. GC12730 Pazopanib Hydrochloride A multi-kinase inhibitor
  15. GC14005 AZD4547 A selective inhibitor of FGFR tyrosine kinases
  16. GC17283 AP26113 A potent ALK inhibitor
  17. GC14396 Ponatinib (AP24534) An inhibitor of native and mutant Bcr-Abl
  18. GC16732 TSU-68 (SU6668,Orantinib) An inhibitor of select receptor tyrosine kinases
  19. GC15454 Lenvatinib (E7080)

    An inhibitor of VEGFR2 and VEGFR3
  20. GC13547 Dovitinib (TKI-258, CHIR-258) A multi-kinase inhibitor
  21. GC13410 Masitinib (AB1010) An inhibitor of c-Kit
  22. GC17943 PD 173074 Inhibitor of tyrosine kinase activity of fibroblast growth factor receptors
  23. GC11705 Nintedanib (BIBF 1120) A VEGFR, FGFR, and PDGFR inhibitor
  24. GC12776 SKLB610 An inhibitor of VEGFR2
  25. GC11622 TG 100801 TG 100801 是一种前药，可通过在开发过程中的去酯化作用产生 TG 100572，以治疗年龄相关性黄斑变性。 TG 100572 是一种多靶点激酶抑制剂，可抑制受体酪氨酸激酶和 Src 激酶；对于 VEGFR1、VEGFR2、FGFR1、FGFR2、PDGFRβ、Fgr、Fyn、Hck、Lck、Lyn、Src、Yes ， 分别。
  26. GC14660 SU 5402 An inhibitor of VEGFR2, FGFR1, and PDGFRβ
  27. GC16028 NVP-BGJ398 phosphate NVP-BGJ398 phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) 是一种有效的 FGFR 家族抑制剂，对 FGFR1、FGFR2、FGFR3 和 FGFR4 的 IC50 分别为 0.9 nM、1.4 nM、1 nM 和 60 nM。
  28. GC13424 LY2874455 A pan-FGFR inhibitor
  29. GC12149 E-3810 E-3810 (E-3810) 是一种新型的 VEGFR 和 FGFR 双重抑制剂，有效且选择性地抑制 VEGFR1、VEGFR2、VEGFR3、FGFR1 和 FGFR2，IC50 为 7 nM、25 nM、10 nM、17.5 nM 和 82.5 nM，分别。
  30. GC14592 KW 2449 A multi-kinase inhibitor
  31. GC15217 Danusertib (PHA-739358) A pan-Aurora kinase and Abl inhibitor
  32. GC16519 ENMD-2076 A multi-kinase inhibitor
  33. GC12145 ENMD-2076 L-(+)-Tartaric acid ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂，对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
  34. GC13848 LY2784544 Potent inhibitor of JAK2
  35. GC16327 Pazopanib (GW-786034) A multi-kinase inhibitor
  36. GC10055 BGJ398 An FGFR inhibitor
  37. GN10540 Fumalic acid A phenol with diverse biological activities
  38. GN10527 Formononetin An isoflavone

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