GSK-3(糖原合成酶激酶3)
GSK3 (glycogen synthase kinase-3) is a serine/threonine protein kinase which contributes to cell survival, diabetes, insulin resistance and Alzheimer's diseases.
- Cat.No. 产品名称 Information
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GC26049
WAY-119064
WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.
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GC66035
GSK3-IN-1
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GC66032
GSK-3β inhibitor 11
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GC65375
Phospho-Glycogen Synthase Peptide-2(substrate) TFA
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GC63446
PF-04802367
PF-04802367 (PF-367) is a highly selective Glycogen synthase kinase-3 (GSK-3) inhibitor with IC50s of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.
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GC63181
SAR502250
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GC62875
BRD3731
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GC62736
(E/Z)-GSK-3β inhibitor 1
(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers, in which GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor with an IC50 of 4.19 nM.
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GC62661
PF-07104091 hydrate
PF-07104091 hydrate 是一种高效选择性的 CDK2/cyclin E1 和 GSK3β 抑制剂,其 Ki 分别为 1.16 和 537.81 nM。PF-07104091 hydrate 对细胞周期素扩增的癌症具有抗肿瘤活性,来自专利 WO2020157652A2。
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GC62660
PF-07104091
PF-07104091 is a CDK2/cyclin E1 inhibitor, a selective ATP-site inhibitor targeting the cyclin-bound activated state of the kinase [1].
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GC62423
GSK-3/CDK5/CDK2-IN-1
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GC62338
GSK-3β inhibitor 3
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GC61925
hSMG-1 inhibitor 11j
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GC39181
BRD0705
BRD0705 is a potent, paralog selective and orally active inhibitor of GSK3α (Glycogen synthase kinase 3α) with IC50 of 66 nM and Kd of 4.8 μM. BRD0705 also inhibits GSK3β with IC50 of 515 nM. BRD0705 can be used for acute myeloid leukemia (AML).
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GC39152
9-ING-41
A GSK3β inhibitor
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GC38892
BIP-135
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GC38787
GNF4877
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GC38330
EHT 5372
EHT 5372 是双特异性酪氨酸磷酸化调节酶 (DYRK) 的强效抑制剂,其 IC50 值分别为 0.22,0.28 nM。
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GC37924
VP3.15 dihydrobromide
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GC37923
VP3.15
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GC37523
RGB-286638 free base
A multi-kinase inhibitor
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GC37522
RGB-286638
A multi-kinase inhibitor
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GC36313
Indirubin-5-sulfonate
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GC36312
Indirubin-3'-monoxime-5-sulphonic acid
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GC36193
GSK-3β inhibitor 1
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GC36190
GSK-3 inhibitor 1
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GC35162
5-Iodo-indirubin-3'-monoxime
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GC15841
Alsterpaullone
A dual CDK and GSK3 inhibitor
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GC13176
CP21R7
A GSK3β inhibitor used to differentiate stem cells
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GC10752
Bikinin
An inhibitor of Arabidopsis shaggy-related kinases
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GC16617
IM-12
A GSK3β inhibitor
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GC15642
CHIR 99021 trihydrochloride
A selective GSK3 inhibitor
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GC13576
TC-G 24
TC-G 24 (Compound 24) 是一种有效的、选择性的糖原合酶激酶-3β (GSK-3β) 抑制剂,IC50 为 17.1 nM。
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GC14306
3F8
3F8 是一种有效且选择性的 GSK-3β 抑制剂,可用作 GSK3 相关疾病的新试剂和潜在治疗候选物。
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GC14233
BIO-acetoxime
A potent, selective inhibitor of GSK3α/β
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GC11627
TCS 2002
TCS 2002 (Compound 9b) 是一种高选择性、口服生物利用度和有效的 GSK-3β;抑制剂,IC50 为 35 nM。
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GC10336
A 1070722
A GSK3β inhibitor
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GC12661
Indirubin-3'-oxime
Inhibitor of GSK3β and cyclin-dependent kinases
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GC11515
TCS 184
TCS 184 是一个多肽片段。
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GC10573
L803-mts
Selective peptide inhibitor of glycogen synthase kinase-3 (GSK-3)
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GC10440
TCS 183
competitive inhibitor of GSK-3β (Ser9) phosphorylation
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GC17457
FRATide
GSK-3 inhibitor
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GC14182
Kenpaullone
A inhibitor of cyclin-dependent kinase and GSK3β
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GC13907
1-Azakenpaullone
A potent inhibitor of GSK3β
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GC14987
GSK-3 Inhibitor IX (BIO)
A potent, selective, and reversible GSK3 inhibitor
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GC14465
Tideglusib
A neuroactive thiadiazolidinone
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GC16568
AZD1080
A potent inhibitor of GSK3α and GSK3β
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GC14840
TDZD-8
A selective inhibitor of GSK3β
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GC17868
TWS119
A GSK3β inhibitor
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GC17690
Cromolyn sodium
A mast cell stabilizer