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Home >> Signaling Pathways >> Stem Cell >> GSK-3

GSK-3(糖原合成酶激酶3)

GSK3 (glycogen synthase kinase-3) is a serine/threonine protein kinase which contributes to cell survival, diabetes, insulin resistance and Alzheimer's diseases.

  1. Cat.No. 产品名称 Information
  2. GC26049 WAY-119064 WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.
  3. GC66035 GSK3-IN-1
  4. GC66032 GSK-3β inhibitor 11
  5. GC65375 Phospho-Glycogen Synthase Peptide-2(substrate) TFA
  6. GC63446 PF-04802367 PF-04802367 (PF-367) is a highly selective Glycogen synthase kinase-3 (GSK-3) inhibitor with IC50s of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.
  7. GC63181 SAR502250
  8. GC62875 BRD3731
  9. GC62736 (E/Z)-GSK-3β inhibitor 1 (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers, in which GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor with an IC50 of 4.19 nM.
  10. GC62661 PF-07104091 hydrate

    PF-07104091 hydrate 是一种高效选择性的 CDK2/cyclin E1 和 GSK3β 抑制剂，其 Ki 分别为 1.16 和 537.81 nM。PF-07104091 hydrate 对细胞周期素扩增的癌症具有抗肿瘤活性，来自专利 WO2020157652A2。
  11. GC62660 PF-07104091 PF-07104091 is a CDK2/cyclin E1 inhibitor, a selective ATP-site inhibitor targeting the cyclin-bound activated state of the kinase [1].
  12. GC62423 GSK-3/CDK5/CDK2-IN-1
  13. GC62338 GSK-3β inhibitor 3
  14. GC61925 hSMG-1 inhibitor 11j
  15. GC39181 BRD0705 BRD0705 is a potent, paralog selective and orally active inhibitor of GSK3α (Glycogen synthase kinase 3α) with IC50 of 66 nM and Kd of 4.8 μM. BRD0705 also inhibits GSK3β with IC50 of 515 nM. BRD0705 can be used for acute myeloid leukemia (AML).
  16. GC39152 9-ING-41 A GSK3β inhibitor
  17. GC38892 BIP-135
  18. GC38787 GNF4877
  19. GC38330 EHT 5372 EHT 5372 是双特异性酪氨酸磷酸化调节酶 (DYRK) 的强效抑制剂，其 IC50 值分别为 0.22，0.28 nM。
  20. GC37924 VP3.15 dihydrobromide
  21. GC37923 VP3.15
  22. GC37523 RGB-286638 free base A multi-kinase inhibitor
  23. GC37522 RGB-286638 A multi-kinase inhibitor
  24. GC36313 Indirubin-5-sulfonate
  25. GC36312 Indirubin-3'-monoxime-5-sulphonic acid
  26. GC36193 GSK-3β inhibitor 1
  27. GC36190 GSK-3 inhibitor 1
  28. GC35162 5-Iodo-indirubin-3'-monoxime
  29. GC15841 Alsterpaullone A dual CDK and GSK3 inhibitor
  30. GC13176 CP21R7 A GSK3β inhibitor used to differentiate stem cells
  31. GC10752 Bikinin An inhibitor of Arabidopsis shaggy-related kinases
  32. GC16617 IM-12 A GSK3β inhibitor
  33. GC15642 CHIR 99021 trihydrochloride A selective GSK3 inhibitor
  34. GC13576 TC-G 24 TC-G 24 (Compound 24) 是一种有效的、选择性的糖原合酶激酶-3β (GSK-3β) 抑制剂，IC50 为 17.1 nM。
  35. GC14306 3F8 3F8 是一种有效且选择性的 GSK-3β 抑制剂，可用作 GSK3 相关疾病的新试剂和潜在治疗候选物。
  36. GC14233 BIO-acetoxime A potent, selective inhibitor of GSK3α/β
  37. GC11627 TCS 2002 TCS 2002 (Compound 9b) 是一种高选择性、口服生物利用度和有效的 GSK-3β；抑制剂，IC50 为 35 nM。
  38. GC10336 A 1070722 A GSK3β inhibitor
  39. GC12661 Indirubin-3'-oxime Inhibitor of GSK3β and cyclin-dependent kinases
  40. GC11515 TCS 184 TCS 184 是一个多肽片段。
  41. GC10573 L803-mts Selective peptide inhibitor of glycogen synthase kinase-3 (GSK-3)
  42. GC10440 TCS 183 competitive inhibitor of GSK-3β (Ser9) phosphorylation
  43. GC17457 FRATide GSK-3 inhibitor
  44. GC14182 Kenpaullone A inhibitor of cyclin-dependent kinase and GSK3β
  45. GC13907 1-Azakenpaullone A potent inhibitor of GSK3β
  46. GC14987 GSK-3 Inhibitor IX (BIO) A potent, selective, and reversible GSK3 inhibitor
  47. GC14465 Tideglusib A neuroactive thiadiazolidinone
  48. GC16568 AZD1080 A potent inhibitor of GSK3α and GSK3β
  49. GC14840 TDZD-8 A selective inhibitor of GSK3β
  50. GC17868 TWS119 A GSK3β inhibitor
  51. GC17690 Cromolyn sodium A mast cell stabilizer

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