Hippo Signaling(Hippo信号通路)

Hippo signaling is a conserved pathway for organ size control by modulating cell proliferation, apoptosis and tissue-specific stem cell regeneration. It is associated with carcinogenesis.

Products for Hippo Signaling

Cat.No. 产品名称 Information
GC73860 JA310 JA310是一种高选择性MST3激酶抑制剂。
GC69261 IHMT-MST1-58 IHMT-MST1-58 是一种有效的、选择性的 STE20-like protein 1 kinase (MST1) 抑制剂，具有口服活性，IC50 值为 23 nM。IHMT-MST1-58 可用于 1 型或 2 型糖尿病的研究。
GC61410 I3MT-3
HMPSNE
I3MT-3 (HMPSNE, compound 3) is a potent, selective, and cell-membrane permeable inhibitor of 3-mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 μM. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
GC32914 EMT inhibitor-1 EMTinhibitor-1是Hippo，TGF-β和Wnt信号通路的抑制剂，并拥有抗肿瘤活性。
GC11245 XMU-MP-1 XMU-MP-1是可逆的、选择性的MST1/2激酶的抑制剂，对MST1和MST2的IC₅₀分别为71.1±12.9 nM和38.1±6.9 nM。
GC14482 Verteporfin
维替泊芬; CL 318952
维替泊芬是一种有效的 PD-L1 表达抑制剂，用于治疗年龄相关性黄斑变性、鲜红斑痣和癌症。