Hippo Signaling(Hippo信号通路)

Hippo signaling is a conserved pathway for organ size control by modulating cell proliferation, apoptosis and tissue-specific stem cell regeneration. It is associated with carcinogenesis.

Cat.No. 产品名称 Information
GC69261 IHMT-MST1-58 IHMT-MST1-58 是一种有效的、选择性的 STE20-like protein 1 kinase (MST1) 抑制剂，具有口服活性，IC50 值为 23 nM。IHMT-MST1-58 可用于 1 型或 2 型糖尿病的研究。
GC61410 I3MT-3 I3MT-3 (HMPSNE, compound 3) is a potent, selective, and cell-membrane permeable inhibitor of 3-mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 μM. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
GC32914 EMT inhibitor-1 EMTinhibitor-1是Hippo，TGF-β和Wnt信号通路的抑制剂，并拥有抗肿瘤活性。
GC11245 XMU-MP-1 An inhibitor of MST1 and MST2
GC14482 Verteporfin
A photosensitizer