Hippo Signaling(Hippo信号通路)
Hippo signaling is a conserved pathway for organ size control by modulating cell proliferation, apoptosis and tissue-specific stem cell regeneration. It is associated with carcinogenesis.
- Cat.No. 产品名称 Information
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GC69261
IHMT-MST1-58
IHMT-MST1-58 是一种有效的、选择性的 STE20-like protein 1 kinase (MST1) 抑制剂,具有口服活性,IC50 值为 23 nM。IHMT-MST1-58 可用于 1 型或 2 型糖尿病的研究。
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GC61410
I3MT-3
I3MT-3 (HMPSNE, compound 3) is a potent, selective, and cell-membrane permeable inhibitor of 3-mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 μM. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
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GC32914
EMT inhibitor-1
EMTinhibitor-1是Hippo,TGF-β和Wnt信号通路的抑制剂,并拥有抗肿瘤活性。
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GC11245
XMU-MP-1
An inhibitor of MST1 and MST2
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GC14482
Verteporfin
A photosensitizer