G-quadruplex(G-四联体)
G-quadruplexes are four-stranded DNA structures that generated from guanine-rich DNA. It is reported to be essential for transcriptional regulation, DNA replication and genome stability in mammalian genome.
- Cat.No. 产品名称 Information
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GC68021
BMVC
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GC65887
SOP1812
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GC64591
MM41
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GC63977
BMVC2
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GC48016
Pyridostatin (trifluoroacetate salt)
A stabilizer of G-quadruplexes
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GC37043
Pyridostatin hydrochloride
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GC32743
Phen-DC3 Trifluoromethanesulfonate (Phen-DC3 Triflate)
Phen-DC3 Trifluoromethanesulfonate is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65 ± 6 and 50 ± 10 nM, respectively.
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GC12092
TMPyP4 tosylate
A telomerase inhibitor
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GC15162
Pyridostatin
A stabilizer of G-quadruplexes
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GC10115
360A iodide
360A iodide 是 G-quadruplex 的选择性稳定剂,也抑制端粒酶活性,在 TRAP-G4 试验中对端粒酶的 IC50 为 300 nM。
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GC15389
360A
360A 是 G-quadruplex 的选择性稳定剂,也抑制端粒酶活性,在 TRAP-G4 试验中对端粒酶的 IC50 为 300 nM。