G-quadruplex(G-四联体)

G-quadruplexes are four-stranded DNA structures that generated from guanine-rich DNA. It is reported to be essential for transcriptional regulation, DNA replication and genome stability in mammalian genome.

Cat.No. 产品名称 Information
GC68021 BMVC
GC65887 SOP1812
GC64591 MM41
GC63977 BMVC2
GC48016 Pyridostatin (trifluoroacetate salt) A stabilizer of G-quadruplexes
GC37043 Pyridostatin hydrochloride
GC32743 Phen-DC3 Trifluoromethanesulfonate (Phen-DC3 Triflate) Phen-DC3 Trifluoromethanesulfonate is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65 ± 6 and 50 ± 10 nM, respectively.
GC12092 TMPyP4 tosylate A telomerase inhibitor
GC15162 Pyridostatin
A stabilizer of G-quadruplexes
GC10115 360A iodide 360A iodide 是 G-quadruplex 的选择性稳定剂，也抑制端粒酶活性，在 TRAP-G4 试验中对端粒酶的 IC50 为 300 nM。
GC15389 360A 360A 是 G-quadruplex 的选择性稳定剂，也抑制端粒酶活性，在 TRAP-G4 试验中对端粒酶的 IC50 为 300 nM。