c-Myc
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation.
- Cat.No. 产品名称 Information
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GC65331
IZCZ-3
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GC65188
IRES-C11
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GC64562
VPC-70619
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GC63576
10074-A4
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GC62594
hnRNPK-IN-1
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GC62287
EN4
EN4, a covalent ligand that targets cysteine 171 (C171) of MYC, is selective for c-MYC over N-MYC and L-MYC. EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis.
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GC61870
NY2267
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GC61014
Lusianthridin
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GC60259
MYCMI-6
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GC38845
sAJM589
-
GC38589
MYCi361
MYCi361 is a MYC inhibitor that engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 binds to MYC with Kd of 3.2 μM. MYCi361 suppresses in vivo tumor growth, increases tumor immune cell infiltration, upregulates PD-L1 on tumors, and sensitizes tumors to anti-PD1 immunotherapy.
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GC38588
MYCi975
MYCi975 (NUCC-0200975) is a potent, selective and orally active inhibitor of MYC that disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression. MYCi975 exhibits potent anti-tumor activities.
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GC34094
Mycro 3
Mycro 3 is a potent and selective inhibitor of c-Myc in whole cell assays. Mycro 3 also shows weak inhibitory activity against AP-1.
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GC33377
KSI-3716
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GC32785
ML327
ML327 is an isoxazole compound that blocks MYC expression and tumor formation in neuroblastoma. ML327 also restores E-cadherin expression with In-Cell Western EC50 of 1.0 μM. ML327 induces apoptosis.
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GC32692
APTO-253 (LOR-253)
APTO-253 (LOR-253) (LOR-253) 是一种小分子,可抑制 c-Myc 表达,稳定 G-四链体 DNA,并诱导急性髓性白血病细胞的细胞周期停滞和凋亡。
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GC14918
10074-G5
An inhibitor of c-Myc/Max dimerization
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GC14413
KJ Pyr 9
An inhibitor of c-Myc and v-Myc interaction with Max
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GC17839
Stauprimide
Primes stem cells for differentiation
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GC17295
10058-F4
A c-Myc inhibitor