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E1 enzyme(E1酶)

E1 activating enzymes initiate the cascade for conjugation of ubiquitin or ubiquitin-like proteins onto the target proteins by activating respective modifiers. It plays important roles in cysteine/thiamine/molybdenum cofactor synthesis etc.

  1. Cat.No. 产品名称 Information
  2. GC17801 PYZD-4409 PYZD-4409 是泛素激活酶 UBA1 的特异性抑制剂,IC50 为 20 μM(无细胞酶测定)。 PYZD-4409 在恶性细胞中诱导细胞死亡并优先抑制原发性急性髓细胞白血病细胞的克隆形成。

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