Chk(细胞周期检查点激酶)

Cat.No. 产品名称 Information

GC11022 SB 218078 A potent Chk1 inhibitor

GC14772 CCT244747

3-[(1R)-2-(二甲基氨基)-1-甲基乙氧基]-5-[[4-甲氧基-5-(1-甲基-1H-吡唑-4-基)-2-吡啶基]氨基]-2-吡嗪甲腈

A potent Chk1 inhibitor

GC13448 NSC 109555 ditosylate An inhibitor of Chk2

GC10793 TCS 2312 checkpoint kinase 1 (chk1) inhibitor

GC15663 LY2606368

5-[[5-[2-(3-氨基丙氧基)-6-甲氧基苯基]-1H-吡唑-3-基]氨基]-2-吡嗪甲腈,LY2606368

LY2606368 是一种 ATP 竞争性 CHK1 抑制剂，目前处于临床阶段，Ki 为 0.9 nM，IC50 <1 nM。

GC11648 BML-277

Chk2 Inhibitor II

A selective DNA damage control kinase inhibitor

GC14234 PF-477736

PF 00477736

A selective inhibitor of checkpoint kinase 1

GC15741 LY2603618

LY2603618; IC-83

A Chk1 inhibitor

GC15739 CHIR-124

4-[((3S)-1-氮杂双环[2,2,2]辛-3-基)氨基]-3-(1H-苯并咪唑-2-基)-6-氯喹啉-2(1H)-酮

A selective Chk1 inhibitor

GC16374 MK-8776(SCH-900776)

6-溴-3-(1-甲基-1H-吡唑-4-基)-5-(3R)-3-哌啶基吡唑并[1,5-A]嘧啶-7-胺,MK-8776

A selective Chk1 inhibitor

GC10546 AZD7762

3-[(氨基羰基)氨基]-5-(3-氟苯基)-N-(3S)-3-哌啶基-2-噻吩羧胺

A selective checkpoint kinase inhibitor

GC17105 CCT241533 hydrochloride

CCT241533盐酸盐,CCT-241533 hydrochloride;CCT 241533 hydrochloride

A selective Chk2 inhibitor

GC18053 CCT241533

(3R,4S)-4-[[2-(5-氟-2-羟基苯基)-6,7-二甲氧基-4-喹唑啉基]氨基]-ALPHA,ALPHA-二甲基-3-吡咯烷甲醇,CCT 241533;CCT-241533

A selective Chk2 inhibitor

Products for Chk