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Home >> Signaling Pathways >> GPCR/G protein >> Endothelin Receptor

Endothelin Receptor(内皮素受体)

Endothelin receptors are members of rhodopsin-like g-protein coupled receptor (GPCRA) with 4 types (ETA, ETB1, ETB2 and ETC), which mediate various physiological processes including vasoconstriction, vasodilation, and neurotransmission etc.

  1. Cat.No. 产品名称 Information
  2. GC64457 Endothelin 1 (swine, human) (TFA)
  3. GC63837 Ro 46-8443
  4. GC61118 Nebentan potassium
  5. GC60544 A-192621
  6. GC60266 Nebentan free base
  7. GC60094 BQ-3020 TFA
  8. GC50247 A 127722 Highly potent, selective ETA antagonist; orally bioavailable
  9. GC45723 Macitentan-d4 An internal standard for the quantification of macitentan
  10. GC38641 IRL-1620 TFA
  11. GC37644 Sitaxsentan
  12. GC36525 Macitentan n-butyl analogue
  13. GC35811 Darusentan An ETA receptor antagonist
  14. GC35546 BQ-788 A peptide ETB receptor antagonist
  15. GC35426 Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
  16. GC35424 Atrasentan
  17. GC34031 PD-159020
  18. GC34025 Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
  19. GC34023 Atrial Natriuretic Peptide (ANP) (1-28), human, porcine An atrial natriuretic peptide
  20. GC32556 ZD-1611
  21. GC32548 Aminaftone (Aminaftone)
  22. GC32528 Ro 46-2005
  23. GC32479 Sparsentan (RE-021) A dual antagonist of AT1 and ETA
  24. GC30942 Tezosentan (RO 610612)
  25. GC30937 IRL-1620 A peptide ETB receptor agonist
  26. GC30577 Endothelin Mordulator 1
  27. GC30485 Endothelin 1 swine, human

    Endothelin 1 (swine, human) is a 21aa peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively).
  28. GC18501 Kendomycin A cytotoxic macrolide
  29. GC11314 Atrial natriuretic factor (1-28) (rat) Atrial natriuretic factor (1-28) (rat) 是大鼠体内 ANP 的主要循环形式，以浓度依赖性方式有效抑制血管紧张素 II (Ang II) 刺激的 endothelin-1 分泌。
  30. GC13175 Sarafotoxin S6a Sarafotoxin S6a 是一种 sarafotoxin 类似物，是一种内皮素受体激动剂，具有与 Endothelin-3 相似的 ETA/ETB 选择性特征。
  31. GC14678 Sarafotoxin S6b Sarafotoxin S6b 是一种血管收缩肽和非选择性内皮素受体激动剂。
  32. GC13924 Endothelin 3 (human, rat) A peptide vasoconstrictor
  33. GC15246 IRL-2500 IRL-2500 是一种有效的内皮素受体拮抗剂。
  34. GC15887 BQ-123 A peptide ETA receptor antagonist
  35. GC12231 Sulfisoxazole An antibiotic and endothelin receptor antagonist
  36. GC11465 Bosentan Hydrate An antagonist of endothelin receptors
  37. GC16269 Bosentan An antagonist of endothelin receptors
  38. GC17184 Ambrisentan An ETA receptor antagonist
  39. GC17769 Sitaxentan sodium A potent ETA receptor antagonist
  40. GC13236 ACT-132577 A dual ETA and ETB receptor antagonist and an active metabolite of macitentan
  41. GC15916 BQ-788 sodium salt A peptide ETB receptor antagonist
  42. GC17785 Macitentan A dual ETA/ETB receptor antagonist
  43. GC16862 Zibotentan (ZD4054) A selective ETA receptor antagonist
  44. GC11405 Avosentan Avosentan (Ro 67-0565; SPP-301) 是一种有效的选择性内皮素受体 (ETA 受体) 拮抗剂。
  45. GC11783 Atrasentan hydrochloride Atrasentan hydrochloride (ABT-627 hydrochloride) 是一种选择性内皮素 A 受体拮抗剂，对 ETA 的 IC50 为 0.0551 nM。

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