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Home >> Signaling Pathways >> GPCR/G protein >> Glucagon Receptor

Glucagon Receptor(胰高血糖素受体)

Glucagon receptor is a member of the class B G-protein coupled family of receptors and is activated by glucagon, resulting in activation of adenylate cyclase and increased levels of intracellular cAMP.

  1. Cat.No. 产品名称 Information
  2. GC26027 V-0219 V-0219 is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), can be used for obesity-associated diabetes research.
  3. GC25046 Albiglutide Fragment Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).
  4. GC62753 [Des-His1,Glu9]-Glucagon amide TFA
  5. GC61545 GLP-1(28-36)amide
  6. GC61540 GLP-1(32-36)amide
  7. GC60877 GLP-2(3-33)
  8. GC60876 GLP-1(7-36), amide TFA
  9. GC60829 Exendin-3/4 (59-86)
  10. GC39364 Cotadutide acetate
  11. GC39323 {Val1}-Exendin-3/4
  12. GC38832 PF-06882961 Danuglipron (PF-06882961), a non-peptide agonist, activates the canonical G protein signaling activity only in the Glucagon-like peptide-1 (GLP-1) receptor with Trp33ECD.
  13. GC38495 Secretin (33-59), rat TFA
  14. GC38133 Tirzepatide (TFA)
  15. GC38132 Tirzepatide hydrochloride
  16. GC37929 VU0453379
  17. GC36753 NNC-0640
  18. GC36152 Glucagon-like peptide 1 (1-37), human (TFA)
  19. GC36150 Glucagon-Like Peptide (GLP) I (7-36), amide, human
  20. GC36148 GLP-1R Antagonist 1
  21. GC36147 GLP-1 receptor agonist 2
  22. GC43761 GLP-1 (1-37) (human, rat, mouse, bovine) (trifluoroacetate salt) An incretin hormone
  23. GC43644 Exendin-4 (acetate) A GLP-1R agonist
  24. GC34904 GLP-1(7-37) acetate
  25. GC34840 Tirzepatide
  26. GP21258 Glucagon (1-29), bovine, human, porcine 胰高血糖素是一种由 29 个氨基酸组成的肽，由胰腺 α 细胞分泌，以响应低血糖水平。
  27. GC34328 Semaglutide TFA Semaglutide (Rybelsus, Ozempic, NN9535, OG217SC, NNC 0113-0217), a long-acting glucagon-like peptide 1 (GLP-1) analogue, is a GLP-1 receptor agonist with the potential for the treatment of type 2 diabetes mellitus (T2DM).
  28. GC34249 KQMEEEAVRLFIEWLKNGGPSSGAPPPS
  29. GC34246 FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
  30. GC34245 GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
  31. GC34244 GLP-1 moiety from Dulaglutide
  32. GC33759 GLP-1(7-36) Acetate (Human GLP-1-(7-36)-amide Acetate)
  33. GC33757 Glucagon (Porcine glucagon)
  34. GC31436 HAEGTFTSD
  35. GC31416 HAEGTFTSDVS
  36. GC31404 Semaglutide A GLP-1R agonist
  37. GC31379 GRA Ex-25

    GRAEx-25是一种glucagon受体的抑制剂，抑制大鼠和人的glucagon受体，IC50值分别为56和55nM。
  38. GC31363 GLP-1 receptor agonist 1
  39. GC31360 Taspoglutide (ITM077)
  40. GC31343 LGD-6972
  41. GC31334 Lixisenatide Lixisenatide (Lyxumia, Adlyxin, ZP10A peptide, AVE0010) is a once-daily short-acting glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1RA) with an IC50 of 1.4 nM for the human GLP-1 receptor in receptor binding studies.
  42. GC31322 Adomeglivant (LY2409021)

    An allosteric antagonist of the glucagon receptor
  43. GC30254 HAEGTFT
  44. GC30058 GLP-1(7-37) An incretin hormone
  45. GC19170 Glucagon receptor antagonists-4 A GCGR antagonist
  46. GC10311 Liraglutide A potent agonist of the GLP-1 receptor
  47. GC10075 Methylprednisolone Sodium Succinate A prodrug form of methylprednisolone
  48. GC16232 BETP A positive allosteric modulator of GLP-1R
  49. GC17298 L-168,049 L-168,049 是一种有效的、选择性的、具有口服活性的非竞争性胰高血糖素受体拮抗剂，对人、鼠和犬胰高血糖素受体的 IC50 分别为 3.7 nM、63 nM 和 60 nM。
  50. GC13743 GLP-1 (9-36) amide GLP-1 (9-36) amide 是胰高血糖素样肽 1-(7-36) 酰胺的主要代谢物，由二肽基肽酶 4 (DPP-4) 形成。
  51. GC13075 GLP-2 (rat) A gut peptide hormone antagonist of GLP-2R

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