Melatonin Receptors(褪黑激素受体)
Melatonin Receptor is a G protein-coupled receptor (GPCR) which binds melatonin. Three types of melatonin receptor have been cloned. The MT1 and MT2 receptor subtypes are present in humans and other mammals, while an additional melatonin receptor subtype MT3 has been identified in amphibia and birds. The MT1 subtype's expression in the pars tuberalis of the pituitary gland and suprachiamatic nuclei of the hypothalamus is indicative of melatonin's circadian and reproductive functional involvement. The MT2 subtype's expression in the retina is suggestive of melatonin's effect on the mammalian retina occurring through this receptor. Research suggests that melatonin acts to inhibit the Ca2+-dependent release of dopamine. Melatonin's action in the retina is believed to affect several light-dependent functions, including phagocytosis and photopigment disc shedding.
- Cat.No. 产品名称 Information
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GC68331
Ramelteon metabolite M-II-d3
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GC64204
S-22153
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GC62825
ACH-000143
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GC60241
Melatonin D5
An internal standard for the quantification of melatonin
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GC38844
S26131
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GC37070
Ramelteon metabolite M-II
A mixed isomer preparation of ramelteon metabolite M-II
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GC35270
Agomelatine L(+)-Tartaric acid
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GC35269
Agomelatine hydrochloride
A melatonin receptor agonist and 5-HT2B and 5-HT2C antagonist
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GC30781
Tasimelteon (BMS-214778)
A melatonin receptor agonist
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GC15365
N-Acetylserotonin
The immediate precursor of melatonin
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GC14728
DH 97
An MT2 receptor antagonist
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GC16020
8-M-PDOT
An MT2 receptor agonist
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GC16186
4-P-PDOT
An antagonist of the MT2 receptor
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GC11188
GR 135531
MT3 receptor agonist
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GC17898
Luzindole
A melatonin receptor antagonist
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GC14690
2-Iodomelatonin
A potent MT1 receptor agonist
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GC11288
2-Phenylmelatonin
A MT receptor mixed partial agonist and antagonist
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GC12014
6-Chloromelatonin
6-Chloromelatonin 是一种有效的褪黑激素受体激动剂,具有比褪黑激素更高的代谢稳定性。
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GC13047
N-Acetyltryptamine
A melatonin analog
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GC17981
Agomelatine
A melatonin receptor agonist and 5-HT2B and 5-HT2C antagonist
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GC15053
Ramelteon
A melatonin receptor agonist
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GC15618
Melatonin
An indoleamine neurohormone that entrains circadian rhythms