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Melatonin Receptors(褪黑激素受体)

Melatonin Receptor is a G protein-coupled receptor (GPCR) which binds melatonin. Three types of melatonin receptor have been cloned. The MT1 and MT2 receptor subtypes are present in humans and other mammals, while an additional melatonin receptor subtype MT3 has been identified in amphibia and birds. The MT1 subtype's expression in the pars tuberalis of the pituitary gland and suprachiamatic nuclei of the hypothalamus is indicative of melatonin's circadian and reproductive functional involvement. The MT2 subtype's expression in the retina is suggestive of melatonin's effect on the mammalian retina occurring through this receptor. Research suggests that melatonin acts to inhibit the Ca2+-dependent release of dopamine. Melatonin's action in the retina is believed to affect several light-dependent functions, including phagocytosis and photopigment disc shedding.

  1. Cat.No. 产品名称 Information
  2. GC68331 Ramelteon metabolite M-II-d3
  3. GC64204 S-22153
  4. GC62825 ACH-000143
  5. GC60241 Melatonin D5 An internal standard for the quantification of melatonin
  6. GC38844 S26131
  7. GC37070 Ramelteon metabolite M-II A mixed isomer preparation of ramelteon metabolite M-II
  8. GC35270 Agomelatine L(+)-Tartaric acid
  9. GC35269 Agomelatine hydrochloride A melatonin receptor agonist and 5-HT2B and 5-HT2C antagonist
  10. GC30781 Tasimelteon (BMS-214778)

    A melatonin receptor agonist

  11. GC15365 N-Acetylserotonin The immediate precursor of melatonin
  12. GC14728 DH 97 An MT2 receptor antagonist
  13. GC16020 8-M-PDOT An MT2 receptor agonist
  14. GC16186 4-P-PDOT An antagonist of the MT2 receptor
  15. GC11188 GR 135531 MT3 receptor agonist
  16. GC17898 Luzindole A melatonin receptor antagonist
  17. GC14690 2-Iodomelatonin A potent MT1 receptor agonist
  18. GC11288 2-Phenylmelatonin A MT receptor mixed partial agonist and antagonist
  19. GC12014 6-Chloromelatonin

    6-Chloromelatonin 是一种有效的褪黑激素受体激动剂,具有比褪黑激素更高的代谢稳定性。

  20. GC13047 N-Acetyltryptamine A melatonin analog
  21. GC17981 Agomelatine A melatonin receptor agonist and 5-HT2B and 5-HT2C antagonist
  22. GC15053 Ramelteon A melatonin receptor agonist
  23. GC15618 Melatonin An indoleamine neurohormone that entrains circadian rhythms

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