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Melatonin D5 Sale

(Synonyms: 褪黑素 D5; N-Acetyl-5-methoxytryptamine-d4) 目录号 : GC60241

An internal standard for the quantification of melatonin

Melatonin D5 Chemical Structure

Cas No.:66521-38-8

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5mg
¥4,410.00
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10mg
¥7,110.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Melatonin-d4 is intended for use as an internal standard for the quantification of melatonin by GC- or LC-MS. Melatonin is an indoleamine neurohormone whose levels vary in a daily cycle, thereby allowing the entrainment of the circadian rhythms of several biological functions in animals, plants, and microbes.1 Many biological effects of melatonin are transduced through melatonin receptors, including the MT1, MT2, and MT3 subtypes.1 Melatonin also acts as a powerful antioxidant that protects lipids, proteins, and DNA against oxidative damage.2,3 Glutathione peroxidase, superoxide dismutases, and catalase are upregulated by melatonin, and melatonin scavenges free radicals as a terminal antioxidant.2,3

1.Boutin, J.A., Audinot, V., Ferry, G., et al.Molecular tools to study melatonin pathways and actionsTrends Pharmacol. Sci.26(8)412-419(2005) 2.Reiter, R.J., Tan, D.X., Manchester, L.C., et al.Biochemical reactivity of melatonin with reactive oxygen and nitrogen speciesCell Biochem. Biophys.34(2)237-256(2001) 3.Reiter, R.J., Tang, L., Garcia, J.J., et al.Pharmacological actions of melatonin in oxygen radical pathophysiologyLife Sci.60(25)2255-2271(1997)

Chemical Properties

Cas No. 66521-38-8 SDF
别名 褪黑素 D5; N-Acetyl-5-methoxytryptamine-d4
Canonical SMILES CC(NC([2H])([2H])C([2H])([2H])C1=CNC2=C1C=C(OC)C=C2)=O
分子式 C13H12D4N2O2 分子量 236.3
溶解度 DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 20 mg/ml 储存条件
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
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1 mg 5 mg 10 mg
1 mM 4.2319 mL 21.1595 mL 42.3191 mL
5 mM 0.8464 mL 4.2319 mL 8.4638 mL
10 mM 0.4232 mL 2.116 mL 4.2319 mL
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