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Adiponectin Receptor(脂联素受体)

Two adiponectin receptors (AdipoR1 and AdipoR2) are identified. AdipoR1 is most abundantly expressed in the skeletal muscle. AdipoR2 is mainly expressed in the liver. They are shown to mediate increased AMP kinase and PPAR-a ligand activities, as well as to enhance fatty acid oxidation and glucose uptake by the ligand—adiponectin.

  1. Cat.No. 产品名称 Information
  2. GC35251 AdipoRon hydrochloride AdipoRon hydrochloride 是一种可口服的,特异性的 AdipoR 激动剂,能够与 AdipoR1 和 AdipoR2 结合,Kd 值分别为 1.8 和 3.1 μM。
  3. GC10254 AdipoRon AdipoRon 是一种具有口服活性的特异性 AdipoR 激动剂,与 AdipoR1 和 AdipoR2 结合,Kds 分别为 1.8 和 3.1 μM。
  4. GN10104 Gramine Gramine (Donaxine) 是一种从大芦苇中分离的天然生物碱,作为活性脂联素受体 (AdipoR) 激动剂,对 AdipoR2 和 AdipoR1 的 IC50 分别为 3.2 和 4.2 μM 。

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