mGluR (代谢型谷氨酸受体)
The mGluR (metabotropic glutamate receptor) is a group C GPCR and is active through an indirect metabotropic process.
- Cat.No. 产品名称 Information
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GC67974
L-Glutamine-15N2
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GC65971
L-Glutamine-13C5
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GC65389
Auglurant
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GC65081
CALP1 TFA
-
GC65068
L-Glutamine 15N
-
GC64513
VU0360172
A positive allosteric modulator of mGluR5
-
GC64319
LY487379
-
GC64218
MMPIP
A reversible allosteric antagonist of mGluR7
-
GC63922
AMN082 free base
An allosteric mGluR7 agonist
-
GC63173
RO0711401
-
GC63150
Pomaglumetad methionil hydrochloride
-
GC63008
HTL14242
-
GC61816
LY367385 hydrochloride
-
GC61646
(-)-Camphoric acid
-
GC61537
L-AP4 monohydrate
A selective Group III metabotropic glutamate receptor agonist
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GC60614
AZD 2066 hydrate
-
GC60065
AZD-8529 mesylate
-
GC50612
VU 6001966
VU 6001966 (compound 15m) 是一种有效的可穿过血脑屏障 mGlu2(代谢型谷氨酸受体 2)负变构调节剂,对 mGlu2 和 mGlu3 的 IC50 分别为 78 nM 和 \u003e30 µM。
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GC50598
VU 0424465
VU 0424465 是一种有效的部分 PAM(正变构调节剂)激动剂,用于 mGlu5 介导的 iCa2+ 动员。
-
GC50497
JF-NP-26
JF-NP-26 是 raseglurant 的无活性光笼衍生物,是第一个笼状 mGlu5 受体负变构调节剂。
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GC50245
(+/-)-ADX 71743
Negative allosteric modulator of mGlu7 receptors; brain penetrant
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GC50154
VU 0469650 hydrochloride
A negative allosteric modulator of mGluR1
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GC50150
TASP 0433864
TASP 0433864 是一种代谢型谷氨酸 2 (mGlu2) 受体的选择性正变构调节剂 (PAM),对人和大鼠 mGlu2 受体的 EC50 值分别为 199 nM 和 206 nM。
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GC50144
VU 0409106
VU 0409106 是一种有效的选择性 mGlu5 负变构调节剂 (NAM),IC50 为 24 nM。
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GC50125
ABP 688
A non-competitive antagonist of mGluR5
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GC50087
FTIDC
FTIDC 是一种口服活性、非竞争性、选择性变构代谢型谷氨酸受体 (mGluR) 1 拮抗剂,对人 mGluR1a 的 IC50 为 5.8 nM。
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GC50053
LY 341495 disodium salt
Selective antagonist of mGluR2 and mGluR3
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GC50025
Lamotrigine isethionate
Inhibits glutamate release. Water-soluble salt of lamotrigine
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GC46171
ML-396
A positive allosteric modulator of group III mGluRs
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GC46165
L-Cysteinesulfinic Acid (hydrate)
An excitatory amino acid and mGluR agonist
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GC46092
AZ 12216052
A positive allosteric modulator of mGluR8
-
GC38597
VU0364770 hydrochloride
An mGluR4 and mGluR6 positive allosteric modulator and mGluR5 antagonist
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GC38029
DHPG
An agonist of group I mGluRs
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GC37931
VU6001376
-
GC36509
LY3020371 hydrochloride
-
GC36506
LY2812223
-
GC36504
LY 541850
-
GC36064
Foliglurax
-
GC35446
AZD 2066
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GC34985
(R)-ADX-47273
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GC34963
(1R,2S)-VU0155041
-
GC34859
VU0650786
-
GC34081
FITM
An antagonist of mGluR1
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GC33154
DFMTI (MK5435)
-
GC33146
CFMTI
-
GC31233
AZD 9272
A negative allosteric modulator of mGluR5 receptors
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GC31097
AZD-8529
-
GC31081
BMT-145027
-
GC31077
Foliglurax monohydrochloride (PXT002331 (monohydrochloride))
-
GC31066
LY2794193