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Home >> Signaling Pathways >> GPCR/G protein >> mGluR

mGluR (代谢型谷氨酸受体)

The mGluR (metabotropic glutamate receptor) is a group C GPCR and is active through an indirect metabotropic process.

  1. Cat.No. 产品名称 Information
  2. GC67974 L-Glutamine-15N2
  3. GC65971 L-Glutamine-13C5
  4. GC65389 Auglurant
  5. GC65081 CALP1 TFA
  6. GC65068 L-Glutamine 15N
  7. GC64513 VU0360172 A positive allosteric modulator of mGluR5
  8. GC64319 LY487379
  9. GC64218 MMPIP A reversible allosteric antagonist of mGluR7
  10. GC63922 AMN082 free base An allosteric mGluR7 agonist
  11. GC63173 RO0711401
  12. GC63150 Pomaglumetad methionil hydrochloride
  13. GC63008 HTL14242
  14. GC61816 LY367385 hydrochloride
  15. GC61646 (-)-Camphoric acid
  16. GC61537 L-AP4 monohydrate A selective Group III metabotropic glutamate receptor agonist
  17. GC60614 AZD 2066 hydrate
  18. GC60065 AZD-8529 mesylate
  19. GC50612 VU 6001966 VU 6001966 (compound 15m) 是一种有效的可穿过血脑屏障 mGlu2（代谢型谷氨酸受体 2）负变构调节剂，对 mGlu2 和 mGlu3 的 IC50 分别为 78 nM 和 \u003e30 µM。
  20. GC50598 VU 0424465 VU 0424465 是一种有效的部分 PAM（正变构调节剂）激动剂，用于 mGlu5 介导的 iCa2+ 动员。
  21. GC50497 JF-NP-26 JF-NP-26 是 raseglurant 的无活性光笼衍生物，是第一个笼状 mGlu5 受体负变构调节剂。
  22. GC50245 (+/-)-ADX 71743 Negative allosteric modulator of mGlu7 receptors; brain penetrant
  23. GC50154 VU 0469650 hydrochloride A negative allosteric modulator of mGluR1
  24. GC50150 TASP 0433864 TASP 0433864 是一种代谢型谷氨酸 2 (mGlu2) 受体的选择性正变构调节剂 (PAM)，对人和大鼠 mGlu2 受体的 EC50 值分别为 199 nM 和 206 nM。
  25. GC50144 VU 0409106 VU 0409106 是一种有效的选择性 mGlu5 负变构调节剂 (NAM)，IC50 为 24 nM。
  26. GC50125 ABP 688 A non-competitive antagonist of mGluR5
  27. GC50087 FTIDC FTIDC 是一种口服活性、非竞争性、选择性变构代谢型谷氨酸受体 (mGluR) 1 拮抗剂，对人 mGluR1a 的 IC50 为 5.8 nM。
  28. GC50053 LY 341495 disodium salt Selective antagonist of mGluR2 and mGluR3
  29. GC50025 Lamotrigine isethionate Inhibits glutamate release. Water-soluble salt of lamotrigine
  30. GC46171 ML-396 A positive allosteric modulator of group III mGluRs
  31. GC46165 L-Cysteinesulfinic Acid (hydrate) An excitatory amino acid and mGluR agonist
  32. GC46092 AZ 12216052 A positive allosteric modulator of mGluR8
  33. GC38597 VU0364770 hydrochloride An mGluR4 and mGluR6 positive allosteric modulator and mGluR5 antagonist
  34. GC38029 DHPG An agonist of group I mGluRs
  35. GC37931 VU6001376
  36. GC36509 LY3020371 hydrochloride
  37. GC36506 LY2812223
  38. GC36504 LY 541850
  39. GC36064 Foliglurax
  40. GC35446 AZD 2066
  41. GC34985 (R)-ADX-47273
  42. GC34963 (1R,2S)-VU0155041
  43. GC34859 VU0650786
  44. GC34081 FITM An antagonist of mGluR1
  45. GC33154 DFMTI (MK5435)
  46. GC33146 CFMTI
  47. GC31233 AZD 9272 A negative allosteric modulator of mGluR5 receptors
  48. GC31097 AZD-8529
  49. GC31081 BMT-145027
  50. GC31077 Foliglurax monohydrochloride (PXT002331 (monohydrochloride))
  51. GC31066 LY2794193

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