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EP4 Receptor(EP4受体)

EP4 receptor is a G-protein coupled receptor for prostaglandin E2. It bind to Gαs and activate adenylyl cyclase to stimulate the formation of cAMP and induce smooth muscle relaxation. It may involve in the renal/intestinal/adrenal/uterine function.

  1. Cat.No. 产品名称 Information
  2. GC15662 ONO-AE3-208 An EP4 receptor antagonist
  3. GC16477 MK-2894 MK-2894 是一种有效、选择性、口服活性和高亲和力 (Ki=0.56 nM) 的全拮抗剂,针对 E prostanoid receptor 4 (EP4 receptor) (IC50=2.5 nM)。

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