CCR(趋化因子受体)
CCR2 (C-C chemokine receptor type 2), the receptor for monocyte chemoattractant protein-1 (CCL2), mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.
- Cat.No. 产品名称 Information
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GC25728
PF-4136309
PF-4136309 (INCB8761, PF-04136309) is a potent, selective, and orally bioavailable CCR2 antagonist with an IC50 of 5.2 nM for human CCR2.
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GC67897
CCR8 antagonist 2
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GC67869
RPT193
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GC67788
CCR6 antagonist 1
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GC65990
MLN3126
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GC65213
AZ084
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GC65141
CCR8 antagonist 1
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GC64441
CCR4 antagonist 3
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GC64274
AZD-5672
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GC63857
CCR4 antagonist 3 hydrochloride
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GC63284
AZD-4818
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GC62833
ALK4290
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GC62724
R243
R243 is an inhibitor of Chemokine (C-C motif) receptor 8 (CCR8) signaling and chemotaxis.
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GC62610
Aplaviroc hydrochloride
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GC62412
BI-6901
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GC61879
Nifeviroc
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GC60998
LMD-009
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GC60679
CCR2 antagonist 4
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GC60615
AZD2423
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GC60212
K777
A cysteine protease inhibitor
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GC45714
ZK 756326 (hydrochloride)
A non-peptide agonist of CCR8
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GC37724
TAK-779
An antagonist of CCR5, CXCR3, and CCR2b
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GC37564
RS102895
A chemokine receptor CCR2 antagonist
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GC36880
PF-04634817
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GC36622
MK-0812 Succinate
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GC36306
INCB 3284
An antagonist of the MCP-
1 receptor CCR2 -
GC35650
Cenicriviroc Mesylate
An antagonist of CCR5 and CCR2
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GC35626
CCR4 antagonist 2
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GC35570
BX471 hydrochloride
A selective CCR1 antagonist
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GC35185
7,4'-Dihydroxyflavone
A flavonoid with diverse biological activities
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GC34521
CCR6 inhibitor 1
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GC40197
Pirfenidone-d5
An internal standard for the quantification of pirfenidone
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GC32367
CCR5 antagonist 1
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GC32336
Aplaviroc (AK 602)
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GC32135
TAK-220
A CCR5 antagonist
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GC32017
CCR3 antagonist 1
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GC32010
GW 766994 (GW 994)
An antagonist of CCR3
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GC31996
CCR1 antagonist 1
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GC31911
CCR2 antagonist 3
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GC31893
CCR1 antagonist 8
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GC31744
GSK2239633A
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GC31714
CCR2-RA-[R]
CCR2-RA -[R]能以非竞争性结合的方式抑制CCR2,主要是通过阻断激活相关的构象变化和G蛋白结合界面的形成。
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GC31662
AZD2098
A CCR4 receptor antagonist
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GC31330
CCX140
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GC30560
CCR2 antagonist 1
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GC19101
Cenicriviroc
An antagonist of CCR5 and CCR2
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GC19077
BMS-813160
A dual antagonist of CCR2 and CCR5
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GC18661
Vercirnon
An antagonist of CCR9
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GC14554
J 113863
J 113863 是一种有效的选择性 CCR1 (CD18) 拮抗剂,对人和小鼠 CCR1 受体的 IC50 值分别为 0.9 nM 和 5.8 nM。
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GC11946
SB 297006
A selective antagonist of CCR3