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Home >> Signaling Pathways >> GPCR/G protein >> CCR

CCR(趋化因子受体)

CCR2 (C-C chemokine receptor type 2), the receptor for monocyte chemoattractant protein-1 (CCL2), mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.

  1. Cat.No. 产品名称 Information
  2. GC25728 PF-4136309 PF-4136309 (INCB8761, PF-04136309) is a potent, selective, and orally bioavailable CCR2 antagonist with an IC50 of 5.2 nM for human CCR2.
  3. GC67897 CCR8 antagonist 2
  4. GC67869 RPT193
  5. GC67788 CCR6 antagonist 1
  6. GC65990 MLN3126
  7. GC65213 AZ084
  8. GC65141 CCR8 antagonist 1
  9. GC64441 CCR4 antagonist 3
  10. GC64274 AZD-5672
  11. GC63857 CCR4 antagonist 3 hydrochloride
  12. GC63284 AZD-4818
  13. GC62833 ALK4290
  14. GC62724 R243 R243 is an inhibitor of Chemokine (C-C motif) receptor 8 (CCR8) signaling and chemotaxis.
  15. GC62610 Aplaviroc hydrochloride
  16. GC62412 BI-6901
  17. GC61879 Nifeviroc
  18. GC60998 LMD-009
  19. GC60679 CCR2 antagonist 4
  20. GC60615 AZD2423
  21. GC60212 K777 A cysteine protease inhibitor
  22. GC45714 ZK 756326 (hydrochloride) A non-peptide agonist of CCR8
  23. GC37724 TAK-779 An antagonist of CCR5, CXCR3, and CCR2b
  24. GC37564 RS102895 A chemokine receptor CCR2 antagonist
  25. GC36880 PF-04634817
  26. GC36622 MK-0812 Succinate
  27. GC36306 INCB 3284 An antagonist of the MCP-1 receptor CCR2
  28. GC35650 Cenicriviroc Mesylate An antagonist of CCR5 and CCR2
  29. GC35626 CCR4 antagonist 2
  30. GC35570 BX471 hydrochloride A selective CCR1 antagonist
  31. GC35185 7,4'-Dihydroxyflavone A flavonoid with diverse biological activities
  32. GC34521 CCR6 inhibitor 1
  33. GC40197 Pirfenidone-d5 An internal standard for the quantification of pirfenidone
  34. GC32367 CCR5 antagonist 1
  35. GC32336 Aplaviroc (AK 602)
  36. GC32135 TAK-220 A CCR5 antagonist
  37. GC32017 CCR3 antagonist 1
  38. GC32010 GW 766994 (GW 994) An antagonist of CCR3
  39. GC31996 CCR1 antagonist 1
  40. GC31911 CCR2 antagonist 3
  41. GC31893 CCR1 antagonist 8
  42. GC31744 GSK2239633A
  43. GC31714 CCR2-RA-[R] CCR2-RA -[R]能以非竞争性结合的方式抑制CCR2，主要是通过阻断激活相关的构象变化和G蛋白结合界面的形成。
  44. GC31662 AZD2098 A CCR4 receptor antagonist
  45. GC31330 CCX140
  46. GC30560 CCR2 antagonist 1
  47. GC19101 Cenicriviroc An antagonist of CCR5 and CCR2
  48. GC19077 BMS-813160 A dual antagonist of CCR2 and CCR5
  49. GC18661 Vercirnon An antagonist of CCR9
  50. GC14554 J 113863 J 113863 是一种有效的选择性 CCR1 (CD18) 拮抗剂，对人和小鼠 CCR1 受体的 IC50 值分别为 0.9 nM 和 5.8 nM。
  51. GC11946 SB 297006 A selective antagonist of CCR3

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